Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $140K *

Elevate sales growth in the refrigeration and HVAC/R sectors by driving market development, building key relationships, and implementing effective strategies to maximize customer engagement and produc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$142K - $202K *

Unlock commercial potential by executing transformation workstreams, collaborating with cross-functional teams, and delivering strategic insights to drive measurable results in a healthcare-focused en...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$210K - $240K *

Drive the product vision and strategy, collaborating across teams to create innovative solutions that enhance customer experiences and business growth in a dynamic, remote-first environment...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$263K - $395K *

Join a team that's shaping the future of finance transformation by leading high-impact FP&A engagements, mentoring talent, and driving business development in a dynamic, growth-oriented environment...

3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$90K - $110K *

Lead the charge in optimizing customer operations by enhancing support and service delivery. Drive team performance, improve workflows, and leverage AI to elevate customer experience and satisfaction...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Manage strategic partnerships with top fleet and dealership customers, driving business growth through relationship building, market analysis, and collaboration with internal teams to deliver tailored...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Unlock potential by owning the full sales cycle with large enterprise accounts. Drive new business, expand customer relationships, and position solutions as key strategic partners in AI and cybersecur...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Technical Services

$200K - $225K *

Manage the valuation process for private equity investments, ensuring accuracy and compliance. Collaborate with investment teams and external providers while leading initiatives to enhance valuation p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $150K *

Champion growth by leading strategic business development initiatives, forging partnerships, and driving revenue expansion. Collaborate with executives to align goals and enhance market presence while...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$166K - $238K *

Drive operational excellence across multiple medical centers, overseeing budgets, staffing, and patient care. Collaborate with clinical leaders to enhance service quality and achieve financial goals w...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$166K - $238K *

Join a team that's dedicated to operational excellence in healthcare. Lead multiple medical centers, driving performance and growth while ensuring exceptional patient care and service. Collaborate wit...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $148K *

Drive strategic partner acquisition by generating new business opportunities in workforce payments, focusing on payroll and pension. Collaborate cross-functionally to build a robust pipeline and lead...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Shape the future of residential construction by driving builder demand and expanding market presence. Collaborate with cross-functional teams to deliver growth and foster strong relationships in the M...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that drives strategic operations within the dynamic B2B software sector. Lead key initiatives, manage industry events, and shape performance metrics to scale output and enhance operational...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$76K - $128K *

Champion daily operational excellence by leading a dynamic service team, ensuring safety, quality, and productivity in a fast-paced environment while fostering team engagement and continuous improveme...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Seeking a strategic finance leader to drive enterprise-wide planning, forecasting, and performance management. Collaborate with executives to deliver insights that support growth while enhancing forec...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $160K *

Manage labor and employment legal matters, ensuring compliance and providing strategic counsel. Collaborate with HR and stakeholders to develop solutions, supervise outside counsel, and educate on pol...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$160K - $189K *

Engage with regional health plans and PBMs to drive access strategies, manage contract negotiations, and enhance patient access. Collaborate cross-functionally to optimize pharmacy benefit performance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $210K *

Drive the development of innovative client reporting solutions, collaborating with cross-functional teams to shape product strategy and influence direction within the Managed Account Solutions platfor...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$204K - $220K *

Lead the charge in building a world-class sales enablement function, driving onboarding, training, and content strategy to enhance seller effectiveness and accelerate new hire productivity across a gl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's dedicated to driving growth in healthcare accounts. Leverage your strategic sales expertise to build relationships, identify opportunities, and deliver value in a fast-paced environ...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Champion the development of healthcare marketing tools by guiding cross-functional teams through the product lifecycle, driving innovative features and optimizing user experiences to enhance HCP engag...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$185K - $256K *

Elevate the market growth strategy for biologics research, driving software adoption and AI use cases. Collaborate with global teams and engage with industry leaders to shape the future of molecular t...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.