Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$160K - $200K *

Join a team that's redefining IT leadership, ensuring robust security and operational excellence across global platforms while driving innovation and growth at scale through strategic technology solut...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $150K *

Drive revenue growth by converting prospects into customers through strategic sales initiatives and a deep understanding of fire and life safety solutions, while collaborating with marketing to enhanc...

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$130K - $150K *

Advance your career by leading product strategy for supply chain orchestration. Drive technical decisions, collaborate with cross-functional teams, and leverage AI to enhance workflows, ensuring measu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$142K - $215K *

Elevate your career by driving new business growth in a dynamic sales environment. Own the full sales cycle, collaborate with teams, and exceed revenue goals while engaging with key stakeholders in a...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $200K *

Unlock new opportunities by building strong customer relationships and driving sales growth. Engage with clients to understand their needs, showcase products, and ensure satisfaction while achieving s...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Lead the charge in enhancing client relationships and driving value realization for managed services. Oversee client success strategies, retention, and growth while collaborating cross-functionally to...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$210K - $250K *

Optimize Medicaid operations by delivering strategic leadership, enhancing financial performance, and overseeing high-quality healthcare solutions. Collaborate effectively with teams and stakeholders...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Accelerate progress at driving revenue growth through strategic sales initiatives, building client relationships, and enhancing cybersecurity solutions for organizations, while managing the complete s...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $220K *

The Senior Vice President (SVP) of Medicaid is responsible for the strategic direction, financial performance, and operational execution of Highmark's Medicaid & D-SNP business. This role involves lea...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading business development initiatives in the Assisted Living market. Collaborate with cross-functional teams to drive customer acquisition and revenue growth while managing a dy...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform business development in the Assisted Living market by driving customer acquisition and growth initiatives. Collaborate with cross-functional teams to execute sales plans and support revenue...

Philadelphia, PARemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $110K *

Champion growth by developing strategic partnerships in international airfreight. Drive profitable expansion through client engagement, leveraging expertise in logistics solutions to enhance market pr...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Empower strategic growth by developing and executing business and go-to-market strategies. Collaborate with cross-functional teams to drive market insights, competitive positioning, and actionable pla...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$158K - $328K *

Lead the charge in financial strategy and operational excellence, partnering with executives to drive growth, optimize resources, and enhance decision-making across a complex organization. Foster a cu...

2 weeks ago

  •   15+ years exp.  •   Technical Services

$100K - $120K *

Join a dynamic team to drive revenue by collaborating with account management, presenting technical solutions, and enhancing the sales process. Leverage your expertise in software analysis and custome...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$196K - $353K *

Champion the Northeast Region Oncology Sales team, driving strategy and execution for a groundbreaking mRNA therapy. Lead high-performing teams, foster key relationships, and ensure launch excellence...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Elevate your career by leading global financial operations, ensuring accurate reporting and compliance across multiple entities. Drive innovation in financial systems and processes while mentoring a h...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Elevate your career by leading global financial operations, ensuring accurate reporting and compliance across multiple entities. Drive innovation through AI and optimize financial systems to enhance e...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$229K - $267K *

Optimize consumer acquisition strategies to drive growth and innovation across multiple channels. Lead a high-performing team, manage budgets, and define future goals while ensuring effective executio...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Accelerate growth by leveraging your extensive network to drive new business opportunities. Own the sales cycle from prospecting to closing, while shaping strategies that influence company success and...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $190K *

Lead a dynamic sales team to drive B2B revenue in defense and unmanned systems. Oversee the sales lifecycle, manage key partnerships, and ensure alignment with engineering and marketing to achieve amb...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$200K - $280K *

Lead and expand a global alliance with Accenture through strategic executive engagement, governance, and joint business planning to drive revenue growth and enhance customer success on a worldwide sca...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$135K - $160K *

Drive a unified technical organization to enhance customer support from application discovery to project conversion, focusing on team development, technical selling, and improving customer experiences...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Lead the charge in building a unified technical organization that enhances customer experience through application support and field service, driving project conversions and fostering a culture of con...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.