Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$110K - $130K *

Lead complex projects from inception to completion, ensuring execution excellence and customer satisfaction. Collaborate with teams to develop strategies that streamline processes and optimize project...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$190K - $215K *

Elevate the National Accounts strategy by leading a high-performing team to drive growth, enhance customer partnerships, and achieve financial objectives across Integrated Delivery Networks through st...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$160K - $200K *

Champion enterprise-wide operational excellence by leading Central Operations, integrating reliability, training, and innovation to enhance performance, reduce risk, and drive measurable results acros...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $200K *

Bring your expertise to lead sales strategies and customer development across NCC and VIS product lines, driving profitable growth and enhancing commercial processes while fostering collaboration with...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a team that's driving growth in the pharmaceutical sector. Harness your expertise to identify new opportunities and build strategic customer relationships, ensuring success through collaboration...

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$165K - $185K *

Empower your sales career by building relationships with healthcare providers, driving revenue growth and championing AI-based medical solutions to transform cancer care for patients and physicians...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$246K - $332K *

Transform healthcare by leading national strategic account management efforts. Drive partnerships with key institutions, enhance patient care, and foster cross-functional collaboration to achieve comm...

RemoteRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$118K - $177K *

Champion transformative diagnostics in infectious disease by driving sales growth, building relationships with key stakeholders, and collaborating across teams to enhance market presence and improve p...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$118K - $177K *

Unlock the potential of infectious disease diagnostics by driving sales in a defined territory. Collaborate with clinical leaders to introduce transformative technology, build relationships, and enhan...

Philadelphia, PARemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's transforming software sales by driving technical solutions and creative outreach. Lead the full sales cycle and collaborate cross-functionally to deliver unique insights and busines...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Drive operational excellence as a leader overseeing all hotel functions to ensure superior guest experiences, financial performance, and a culture of engagement, while optimizing team performance in a...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$160K - $200K *

Lead the charge in transforming operations through strategic execution, technology integration, and process optimization to elevate client experiences, enhance scalability, and foster a high-performan...

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$80K - $95K *

Drive your career with a dynamic sales role focused on the full customer journey, from prospecting to closing, in a fast-paced cybersecurity environment. Maximize your impact and earnings while buildi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Transform healthcare engagement by building relationships with HCPs through digital interactions and telephone conversations, promoting products, and achieving sales goals while ensuring compliance wi...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in building and scaling strategic partnerships to drive revenue growth. Oversee the entire partner lifecycle, from selection to enablement, ensuring successful collaboration and measur...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Engage potential clients by developing business strategies, conducting outreach campaigns, and building strong relationships with key decision-makers to drive growth and enhance firm offerings across...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$210K - $250K *

Transform the product marketing landscape by leading go-to-market strategies for cutting-edge AI and cloud solutions. Collaborate cross-functionally to craft compelling narratives that resonate with c...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in developing and executing channel strategies to drive growth, onboard high-performing partners, and enhance relationships with distributors in the life sciences sector...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Join us in leading commercial lines underwriting operations, driving profitability and growth while fostering strong agency relationships. Collaborate with teams to achieve strategic objectives and en...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $237K *

Drive partner sales growth by leading a hands-on team in AMER. Collaborate closely with Account Executives to enhance channel strategies, mentor talent, and transform ambiguity into actionable results...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $134K *

Join our team to drive revenue growth by acquiring new accounts and fostering relationships. You'll engage with key prospects, execute business development strategies, and collaborate cross-functional...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Food & Beverages

$88K - $105K *

Take ownership of a key territory, driving sales growth and operational excellence. Lead a high-performing team, manage client relationships, and ensure profitability while collaborating closely with...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $140K *

Transform enterprise partnerships by leading complex sales cycles, aligning stakeholders, and driving impactful solutions for large educational organizations. Collaborate with executives to enhance op...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$180K - $215K *

Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Drive strategic enterprise sales initiatives across diverse industries, managing complex sales cycles and fostering executive-level relationships to achieve revenue goals and enhance organizational gr...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.