Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$148K - $248K *

Drive growth by leading a field-based sales team focused on federal agencies. You'll strategize, coach, and negotiate to enhance adoption of our DevSecOps platform, ensuring alignment with agency need...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $180K *

Shape the future of customer engagement by leading strategic sales and support initiatives. Drive growth, enhance customer satisfaction, and foster partnerships while overseeing a high-performing team...

RemoteRemote

2 days ago

  •   8 - 10 years exp.  •   Transportation

$132K - $207K *

Engage with North American lenders to drive impactful solutions in consumer lending. Collaborate on client opportunities, articulate value, and lead strategic initiatives to enhance FICO Scores adopti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$196K - $353K *

Empower your career by leading a dynamic oncology sales team to drive regional strategy and execution. Collaborate with partners to launch innovative therapies, build key relationships, and shape the...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of clinical care management by leading strategic operations, optimizing processes, and enhancing patient care. Collaborate with teams to drive performance improvements and ensure comp...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $300K *

Shape the future of financial strategy by leading comprehensive reporting, planning, and analysis. Collaborate with cross-functional teams to enhance decision-making and drive performance, while ensur...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $215K *

Drive regional success by leading launch execution and building high-performing teams. Foster customer relationships and ensure alignment with corporate goals in a fast-paced, entrepreneurial environm...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Advance your career by driving strategic vendor finance relationships in the industrial equipment sector. Lead business development efforts, manage key partnerships, and deliver tailored financing sol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Unlock potential by leading a dynamic sales team, building client relationships, and implementing effective strategies to drive growth. Enjoy flexibility while mentoring others and managing your own p...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Grow your career with us as you lead a dynamic sales team, develop client relationships, and implement effective strategies. Enjoy flexibility in your schedule while making a significant impact in the...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Join a team that's dedicated to empowering clients through tailored insurance solutions. Lead and inspire a sales team while building lasting relationships with business owners. Enjoy flexibility and...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Shape the future of outside sales by leading a dynamic team, building client relationships, and implementing proven strategies. Enjoy flexibility while mentoring others and driving success in a reward...

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $181K *

Accelerate progress at driving SaaS revenue by developing new markets and relationships. Own the sales cycle from prospecting to proposal management, collaborating cross-functionally to deliver value...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead the charge in outside sales by inspiring your team and building client relationships. Utilize your expertise to implement strategies, mentor new members, and provide tailored insurance solutions...

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$350K *

Engage with key enterprise clients to drive revenue growth through strategic, solution-based sales. Develop lasting relationships and navigate complex sales processes while championing company values...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $200K *

Advance your career by leading public policy initiatives and government relations efforts, shaping complex political strategies in a fast-paced environment. Collaborate with teams to drive enterprise...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$140K - $155K *

Engage with strategic enterprise clients to drive retention, growth, and satisfaction. Lead account strategy, advise stakeholders, and deliver measurable outcomes while mentoring team members and fost...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $120K *

Drive new dealer acquisition by managing the full sales cycle, building strong relationships, and executing strategic territory plans to achieve sustainable revenue growth in a competitive automotive...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $180K *

Join a dynamic team as you lead offensive security operations, manage a skilled red team, and enhance security posture through strategic partnerships and advanced adversary simulations in a complex en...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$211K - $272K *

Transform your career by leading enterprise applications strategy and delivery. Collaborate with cross-functional teams to enhance processes, drive AI adoption, and ensure robust application architect...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Take ownership of key client relationships, driving growth in the renewable energy analytics sector while collaborating across teams to support long-term strategic goals and ensure client success with...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $140K *

Partner with us to drive growth in industrial accounts, leveraging your sales expertise to expand relationships and deliver innovative water treatment solutions that meet the needs of our customers an...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $170K *

Partner with us to enhance consultant relationships in healthcare. Drive business growth by cultivating partnerships, optimizing engagement strategies, and aligning internal teams to effectively posit...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $200K *

Lead the charge in driving commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and deliver measurable resul...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Champion business development to foster strategic partnerships in biotech, leveraging technical expertise and market insights to drive multi-million dollar enterprise revenue while shaping innovative...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.