Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$141K - $189K *

Join a dynamic team to drive strategic growth within the Department of Veterans Affairs, leveraging your expertise to build relationships, execute account strategies, and navigate complex procurement...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$210K - $250K *

Champion the evolution of HR Business Partnering globally, driving strategic workforce initiatives and organizational effectiveness while partnering with senior leaders to enhance talent and leadershi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $215K *

Unlock potential by driving organic growth in strategic accounts through deep relationships, cross-portfolio selling, and long-term planning to maximize revenue and customer retention while navigating...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join us in driving growth by acquiring new customers and expanding existing relationships. This field-oriented role requires a motivated hunter skilled in building pipelines and fostering executive co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $145K *

Elevate operational excellence by leading technical escalation and onboarding teams in Managed Services. Drive high-quality service delivery across voice, SD-WAN, and security, ensuring seamless custo...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$116K - $145K *

Join a team that's redefining managed services by leading technical escalations and customer onboarding for voice services. Drive operational excellence and ensure high-quality service delivery across...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Develop and execute innovative product strategies for a global Oil-Flooded compressor portfolio, driving profitable growth through customer insights and cross-functional collaboration to enhance marke...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $170K *

Lead a dynamic sales team to drive innovative HIV treatment strategies. Collaborate with healthcare professionals to develop actionable business plans, foster key relationships, and achieve performanc...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in driving sales success by implementing strategic plans and engaging healthcare professionals. Utilize your expertise to optimize customer interactions and exceed performance objectiv...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join us to lead transformational sales in digital operations, driving complex solutions across cybersecurity and manufacturing. Collaborate with stakeholders to unlock value and accelerate customer ou...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Transform the sales landscape by providing expert technical support and product demonstrations. Collaborate cross-functionally to address customer needs and enhance internal training, driving success...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Shape the future of commercial sales by cultivating relationships with national accounts, driving revenue growth, and leading strategic initiatives to exceed market share goals while ensuring customer...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Accelerate your career by leading sales growth and strategic partnerships in the Executive Benefits sector. Drive revenue, expand market presence, and enhance employee protection through innovative id...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$108K - $135K *

Join a team that's driving innovation and operational excellence in digital services. This role involves project management, cross-functional collaboration, and strategic execution to ensure successfu...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate customer success in the Americas by leading a growing team of CSMs. Drive adoption, value realization, and customer health while shaping playbooks and strategies for scalable growth. Collabora...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$109K - $164K *

Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in shaping Stedi's litigation strategy, driving affirmative disputes and regulatory actions to protect and expand our operational freedom in the healthcare sector. Collaborate with lea...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$109K - $137K *

Lead the development and execution of comprehensive EHS programs, ensuring compliance with regulations and standards. Manage a team, conduct audits, and drive safety initiatives to minimize risks and...

4 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $186K *

Join a team that's dedicated to building strong client relationships while leading strategic initiatives in the retirement industry. Leverage your expertise to educate clients, resolve issues, and dri...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $100K *

Engage with customers and drive revenue growth by managing accounts and pursuing new business opportunities. Utilize consultative selling to achieve sales targets while collaborating with internal tea...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Accelerate revenue growth by driving strategic partnerships and sales initiatives. Own a quota, cultivate executive relationships, and implement market strategies to position the organization as a lea...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$170K - $200K *

Drive excellence in commercial credit oversight, focusing on construction and development lending. Lead risk management, underwriting, and governance while collaborating with senior leadership to ensu...

5 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Drive the sales process from prospecting to close, engaging healthcare leaders to showcase AI solutions that enhance patient access and operational efficiency. Join a dynamic team focused on exceeding...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Transform sales leadership by building and guiding a high-performing team to drive growth and retention in the AMER region, collaborating across departments to execute strategic initiatives and enhanc...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.