Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$105K - $115K *

Empower a dynamic sales team to drive revenue growth through strategic partnerships and innovative territory planning. Shape the future of business development by fostering relationships and deliverin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$110K - $130K *

Lead the charge in transforming talent acquisition by partnering with executives to drive strategic hiring initiatives, manage complex recruitment processes, and enhance candidate experiences across s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$102K - $128K *

Drive operational excellence by leading cross-functional teams to enhance digital pharmacy solutions, optimize processes, and improve customer engagement while fostering a high-performance culture roo...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K *

Empower senior living communities by driving measurable outcomes and adoption. Collaborate with care teams to enhance performance, ensuring impactful use of technology while fostering trusted relation...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving complex sales into Fortune 2000 accounts, engaging with key stakeholders in compliance and technology. Shape the future of AI in enterprise solutions while achieving ambiti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $180K *

Empower customer success by owning post-sale experiences, driving onboarding, adoption, and renewals. Collaborate with cross-functional teams to ensure every user thrives, turning initial deployments...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$168K - $240K *

Lead the charge in optimizing business operations through innovative solutions, driving efficiency and productivity while fostering cross-functional collaboration and data-driven decision-making to en...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$110K - $140K *

Transform regional accounts by developing strategic programs and building strong relationships with local decision-makers. Drive growth through effective budgeting, insights, and innovative solutions...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $110K *

Join a team that's dedicated to enhancing customer satisfaction through effective dealer support and product performance management. Lead initiatives in your territory to foster strong relationships a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's redefining security in an AI-driven world by owning the full sales cycle for mid-sized organizations. Drive growth, foster relationships, and close deals while navigating complex en...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Engage with customers to build relationships and drive sales success. Develop strategic sales plans, forecast accurately, and collaborate with teams to exceed goals while managing accounts effectively...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$155K - $180K *

Drive successful delivery of complex, multi-year programs in a dynamic environment. Collaborate with cross-functional teams to manage scope, budget, and timelines while ensuring client satisfaction an...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in expanding into new healthcare verticals by developing and executing go-to-market strategies, managing partnerships, and driving campaign performance. Collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$66K - $120K *

Drive business growth through your established network and expertise in property restoration. Leverage strong relationships to generate leads and foster referral partnerships for long-term success in...

Reposted yesterday

  •   Less than 5 years exp.  •   Technical Services

$66K - $120K *

Unlock potential by leveraging existing networks to drive business growth in the property restoration industry. Engage with key referral partners and generate leads, fostering strong relationships tha...

Reposted yesterday

  •   Less than 5 years exp.  •   Technical Services

$103K - $141K *

Take ownership of customer success by driving adoption and value realization of the platform. Leverage your technical expertise to guide clients through onboarding and operationalization, ensuring sat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$240K - $318K *

Lead a global BSS engineering team, driving architecture, delivery, and product strategy while ensuring platform performance and compliance across diverse telecommunications solutions...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$180K - $200K *

Drive your career forward by leading centralized inside sales and customer experience teams. Shape strategies, enhance customer interactions, and foster growth across multiple brands while ensuring op...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$130K - $165K *

Accelerate commercial growth by engaging healthcare providers, driving product adoption, and achieving sales goals while navigating a competitive landscape in the biotech industry. Build strong relati...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to enhancing client relationships and driving success. Oversee client performance, mentor staff, and ensure compliance while collaborating with various departments to deli...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in driving revenue through strategic partnerships, enhancing market reach, and delivering customer value across your designated region while managing complex sales cycles and fostering...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$300K - $350K *

Empower your career by driving sales growth in the cybersecurity sector. Build strong customer relationships, acquire new accounts, and exceed sales quotas while managing Channel Partner relationships...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $176K *

Lead the charge in driving strategic growth and retention for global key accounts. Collaborate across functions to enhance customer relationships and execute multi-year account strategies that align w...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$198K - $298K *

Champion the optimization of Sales systems and processes, driving productivity and strategic initiatives. Collaborate with cross-functional teams to enhance the sales experience and lead a global team...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $200K *

Accelerate your career by driving PEO sales growth through client acquisition and relationship management. Collaborate with stakeholders to deliver tailored solutions and enhance market presence while...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.