Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$150K - $235K *
Join a team that's shaping the future of Medical Affairs by driving strategic client engagements and enhancing capabilities. This Director-level role balances client delivery and internal growth, focu...
3 weeks ago
$160K - $200K *
Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...
2 weeks ago
$80K - $95K *
Engage with mid-market clients to drive consultative sales, managing the full cycle from outreach to contract. Build trust with support leaders, demonstrating clear ROI and shaping the sales strategy...
1 week ago
Sr. Product Operations Manager
$110K - $160K *
Drive your career with a strategic role in Product Operations, partnering with leaders to transform complex challenges into actionable insights, while enhancing cross-functional collaboration and leve...
1 week ago
Sales Executive Lead, Enterprise Platforms - Ledger
$133K - $227K *
Empower financial institutions by strategizing and executing innovative ledger solutions. Engage with C-suite executives to drive modernization and enhance operational resilience, while managing the f...
Today
Senior Director, Global Field Operations
$175K - $210K *
Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...
3 weeks ago
Major Accounts Executive, South Central
$150K - $180K *
Partner with us to drive growth in strategic enterprise accounts, managing complex sales cycles and building trust with security-focused buying committees. Leverage technical credibility to close mult...
2 weeks ago
National Enterprise Account Manager
$120K - $150K *
Unlock the potential of strategic accounts as you build lasting relationships, drive retention, and identify growth opportunities. Be the primary advocate for our major enterprise clients, ensuring sa...
Reposted yesterday
Core Enterprise Account Executive TOLA
$222K - $278K *
Drive impactful change by consolidating technologies and digitizing workflows for enterprise customers, while fostering executive relationships and managing complex sales processes that promote safety...
Reposted 2 days ago
Sales Manager, Foodservice K12 - Southeast Region
$123K - $185K *
Lead K-12 sales initiatives in the Southeast, driving growth through strategic partnerships and culinary collaborations while enhancing product placements and bid success across school districts...
4 days ago
Regional Sales Manager - US South Central - Remote
$110K - $150K *
Lead the charge in driving revenue growth by developing new business opportunities and managing client relationships in the robotics and automation sectors, while collaborating with technical teams to...
Yesterday
$92K - $134K *
Join a dynamic team to build client relationships, drive upsell opportunities, and enhance retention through tailored solutions. Leverage your expertise in facilities management and market assessments...
3 weeks ago
DIRECTOR, REGIONAL SALES - TEXAS
$115K - $135K *
Grow your career with leadership in business development, targeting the Behavioral Health sector. Leverage your expertise to drive sales, establish client relationships, and exceed financial goals whi...
Reposted today
Account Executive (HCM, Payroll, Saas, Healthcare)
$76K - $102K *
Engage in a dynamic role driving client acquisition in the Home-Based Care sector. You'll build a robust pipeline, execute sales strategies, and collaborate cross-functionally to enhance client experi...
3 weeks ago
Senior Sales Manager North America
$120K - $145K *
Transform our sales strategy by leading a high-performing team to drive revenue growth, enhance customer engagement, and expand market presence in the North American TEST business. Collaborate cross-f...
Reposted 1 week ago
Enterprise Account Executive (US Market)
$112K - $165K *
Elevate your career by driving enterprise sales, building strategic relationships, and modernizing financial operations for global businesses. Partner with C-suite leaders to enhance their payment sol...
4 weeks ago
Senior Sales Manager, Midwest US
$130K - $150K *
Lead regional sales efforts by developing strategic plans, managing high-performing teams, and strengthening client relationships to drive revenue growth and market penetration effectively...
Reposted 1 week ago
Director of Business Process Excellence
$155K - $205K *
Champion process excellence by optimizing workflows and driving cross-functional improvements. Collaborate with teams to enhance operational efficiency, reduce costs, and elevate service quality throu...
3 weeks ago
Managing Director - Market Development & Revenue Growth (Guidewire InsuranceNow)
$180K - $220K *
Lead the charge in driving growth for our Guidewire InsuranceNow practice by developing strategic relationships, generating new business opportunities, and executing revenue strategies across the US i...
2 weeks ago
Senior Director, Business Development
$150K - $180K *
Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...
1 week ago
Regional Sales Director (Tampa)
$112K - $143K *
Champion new business growth by building strategic partnerships and expanding market share within your territory. Drive revenue through effective relationship management and a proactive sales strategy...
2 weeks ago
Program Manager - United Concordia Dental
$94K - $151K *
Shape the future of enterprise strategy by leading a diverse portfolio of programs and initiatives. Collaborate with cross-functional teams to drive measurable business value and ensure alignment with...
2 weeks ago
Global Enterprise Account Manager
$201K - $239K *
Grow strategic relationships with global enterprise clients, driving EHS and ESG success. Leverage consultative selling to expand accounts, collaborate cross-functionally, and ensure exceptional custo...
6 days ago
$160K - $177K *
Lead the charge in cultivating and expanding high-value global client relationships, driving strategic account plans, and achieving exceptional sales targets in a dynamic SaaS environment...
Reposted today
M3 Sr. Sales Account Executive
$110K - $130K *
Unlock your potential by driving sales growth in the Enterprise ERP market. Engage with diverse clients, manage sales cycles, and foster strategic partnerships to enhance our Digital Transformation pr...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.