Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$160K - $185K *

Join a team that's redefining the SaaS landscape by driving strategic growth and closing high-value deals. Engage with senior leaders, develop a robust pipeline, and collaborate cross-functionally to...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Media

$80K - $95K *

Elevate your sales career by driving full-cycle sales in a dynamic environment. Leverage AI tools and consultative frameworks to engage high-growth organizations, exceed targets, and enhance your prod...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $160K *

Elevate operational excellence in neurosurgery by leading strategic initiatives, driving performance, and fostering a culture of accountability. Collaborate with executive leaders to enhance patient c...

5 days ago

  •   5 - 7 years exp.  •   Staffing

$86K - $135K *

Accelerate progress at driving sales growth by managing key accounts, pursuing new opportunities, and collaborating with cross-functional teams to deliver exceptional customer results in the specialty...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$155K - $410K *

Accelerate progress at driving alliance strategy and sales enablement efforts, fostering executive relationships, and translating market insights into actionable solutions to support revenue growth an...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$155K - $410K *

Transform alliance strategy and sales enablement for Microsoft Dynamics 365, driving revenue growth and client engagement. Lead cross-functional teams to align market insights with actionable sales pl...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$135K - $170K *

Optimize your sales career by managing the full sales cycle for a leading engineering software. Leverage your technical expertise to drive revenue growth and deliver impactful solutions to industrial...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Empower your career as a Sales Manager in the Specialty Fluids sector, driving growth through strategic account management and lead generation while collaborating with diverse teams across North Ameri...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$231K - $363K *

Grow your career with a dynamic sales role focused on building enterprise partnerships. Drive impactful healthcare solutions by engaging with HR leaders and managing the full sales cycle across the No...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive growth by building and expanding enterprise pipelines through strategic outbound efforts and executive networking. Collaborate cross-functionally to secure high-value deals and establish long-te...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $131K *

Lead the charge in driving strategic growth by cultivating customer relationships, optimizing sales channels, and leveraging market insights to enhance product positioning and maximize revenue opportu...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$65K - $108K *

Lead the charge in expanding distribution relationships and driving sales growth. Collaborate with key stakeholders to identify opportunities, enhance client engagement, and optimize strategic initiat...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Drive operational excellence by leading a global team to enhance post-sale services, optimize processes, and ensure customer satisfaction. Collaborate across departments to implement scalable solution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$100K - $120K *

Join a team that's transforming women's health by driving sales in OB/GYN and maternal-fetal medicine. You'll manage the full sales cycle, leveraging existing relationships to expand our reach and ens...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Drive the success of a dynamic sales team by managing daily operations, coaching, and ensuring pipeline health. Collaborate with leadership to translate strategy into actionable priorities while foste...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Unlock potential by driving growth in our Enterprise Content Management business. Engage with diverse stakeholders, navigate complex sales cycles, and expand client relationships across the Midwest wh...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$272K - $340K *

Lead the charge in shaping a global supply chain strategy that ensures seamless delivery of clinical and commercial products. Build a high-performing team and foster partnerships to meet regulatory st...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion the future of revenue operations by leading GTM infrastructure, analytics, and team scaling across multiple verticals. Drive strategic initiatives to enhance efficiency and revenue growth in...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower the Foot and Ankle team by driving growth and building key relationships. Engage with surgeons in the operating room and support sales initiatives to enhance product adoption and customer sati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Transform the supply chain landscape by leading procurement and subcontracting efforts, ensuring compliance with federal regulations while driving efficiency and innovation in support of critical defe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $120K *

Unlock growth potential by managing strategic accounts and cultivating executive relationships. Drive revenue through tailored strategies and consultative selling, while aligning cross-functional team...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Drive productivity and effectiveness in Sales Enablement by developing and executing programs that empower customer-facing teams to achieve revenue goals through strategic training, tools, and support...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $215K *

Lead regional sales initiatives, driving product launch success and team performance. Collaborate cross-functionally to execute strategies, foster customer relationships, and ensure compliance while b...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock your potential in a dynamic sales role focused on driving growth in the natural food colors market. Embrace challenges, travel extensively, and leverage your competitive spirit to achieve unlim...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$244K - $305K *

Drive financial strategy and analysis for global commercialization efforts, partnering with cross-functional teams to enhance decision-making and support successful product launches in the biopharmace...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.