Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$100K - $140K *

Accelerate your career by driving new business growth and managing enterprise client relationships. Leverage your expertise in managed sales solutions to exceed targets and optimize sales processes in...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$150K - $180K *

Drive mutual success as a strategic partner in vendor management, fostering relationships, optimizing revenue growth and aligning business goals through expert collaboration and FinOps knowledge...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Technical Services

$252K - $365K *

Lead the charge in transforming deal governance and renewal operations, driving efficiency and strategic growth across global commercial processes. Collaborate with cross-functional teams to enhance p...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$100K - $120K *

Shape the future of LPG tank sales by driving revenue growth and building lasting relationships across the Western US. Lead customer engagement, execute strategic initiatives, and ensure consistent pe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Transform the beverage and dessert ingredient landscape by driving sales growth, expanding market presence, and fostering strong customer relationships. Collaborate with cross-functional teams to deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$150K - $500K *

Accelerate progress at a leading pharmaceutical engagement firm by driving sales strategy and growth for a new compliance-focused product, Curated. Leverage your extensive network and expertise to bui...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $165K *

Drive growth by leading consultative sales for women's health benefits. Build relationships, tailor solutions, and close deals while managing a strong sales pipeline and collaborating with internal te...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $207K *

Elevate business growth by driving new client acquisitions and expanding existing accounts, while monitoring customer satisfaction and providing operational guidance across multiple plants to ensure s...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$166K - $200K *

Lead the charge in driving strategic growth through complex transactions, acquisitions, and partnerships. Collaborate with teams to enhance operational efficiency and expand market presence while mana...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$115K - $135K *

Lead the charge in driving customer success and growth by managing a portfolio of complex accounts, collaborating with finance and IT leaders to enhance digital transformation and optimize payment sol...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Join a team that's redefining healthcare sales by leading strategic initiatives, managing a high-performing team, and driving revenue growth in the Physical Therapy and Rehab markets. Shape the future...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join our dynamic team as a results-driven Account Executive, where you'll convert qualified leads into long-term customers, manage the full sales cycle, and build strong relationships with key decisio...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $120K *

Empower your career as a Sales Engineer, driving revenue through technical expertise and strategic collaboration. Engage with clients, deliver compelling demos, and streamline the sales process to ach...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $100K *

Deliver exceptional client service by managing strategic accounts, driving retention, and fostering growth. Collaborate with cross-functional teams to address customer needs and expand business opport...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $180K *

Empower business growth by building strategic relationships and originating multifamily loans. Utilize your expertise to manage the loan process, advise clients, and enhance community presence in the...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$174K - $261K *

Empower enterprise transformation by leading a specialized sales team focused on cloud, data, and AI solutions. Drive strategic partnerships, coach high-performing sellers, and enhance technology stra...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$216K - $361K *

Elevate your career by driving sales growth in enterprise software across retail, energy management, and telecommunications. Collaborate with top clients to achieve strategic goals and expand market p...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $105K *

Elevate client relationships by managing post-sale engagements, ensuring project success, and driving account growth. Collaborate with internal teams to deliver value and strengthen partnerships acros...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K *

Join a team that's driving growth by onboarding and activating merchants in the home services sector. This role involves managing the sales process, collaborating cross-functionally, and maintaining a...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate safety standards by leading a comprehensive safety strategy, fostering a proactive culture, and driving continuous improvement across multi-site operations while ensuring compliance with indus...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$175K - $225K *

Lead the charge in shaping product strategy and execution, driving innovation and collaboration across teams to deliver impactful solutions in a fast-paced B2B SaaS environment. Own the product roadma...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$70K - $100K *

Advance customer accounts through strategic sales techniques, collaborating with Sales and Operations teams to drive revenue growth and enhance client relationships in a dynamic, hybrid work environme...

Reposted today

  •   Less than 5 years exp.  •   Transportation

$160K - $190K *

Accelerate progress at senior living communities by leading a high-performing Customer Success team, ensuring measurable outcomes and fostering strong partnerships to enhance care delivery and custome...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.