Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Vice President, Enterprise Business Platforms, Membership Enrollment & Billing
$171K - $326K *
Lead the charge in overseeing department staff, managing budgets, and aligning IT strategies with organizational goals to enhance operational reliability and drive continuous improvement across system...
Today
Sr. Manager, Sales Strategy and Operations - Omni + OBT
$142K - $197K *
Drive strategic improvements and operational efficiency in Partnerships by establishing frameworks, integrating AI solutions, and optimizing team performance, all while collaborating with cross-functi...
Reposted 2 weeks ago
Business Development Representative (BDR) Manager - (US)
$100K - $115K *
Grow and lead a high-performing BDR team, driving pipeline success through strategic coaching and data-driven insights. Collaborate cross-functionally to optimize sales processes and ensure seamless h...
2 weeks ago
$150K - $180K *
Transform operational excellence across multiple agencies, driving growth and compliance while leading high-performing teams. Collaborate strategically to achieve business goals and ensure quality car...
5 days ago
$125K - $150K *
Lead a high-impact RevOps team to optimize and scale operational systems across Sales, Marketing, and Customer Success. Drive AI innovation and streamline processes to enhance productivity and revenue...
3 days ago
Sr. Strategic Account Executive, MarketScan
$239K - $358K *
Join a team that's committed to maximizing growth in pharmaceutical accounts through strategic planning and relationship building, focusing on data-driven solutions and real-world evidence to foster l...
Reposted 3 weeks ago
Regional Vice President of Commerce
$150K - $180K *
Transform your career by driving new revenue growth in diverse industries. As a key sales leader, you'll identify prospects, develop relationships, and deliver tailored marketing solutions, ensuring c...
2 weeks ago
$80K - $125K *
Manage a dynamic sales team to achieve objectives, drive revenue growth, and enhance market presence. Foster a collaborative environment through training and performance reviews while ensuring complia...
4 weeks ago
$160K - $200K *
Drive growth and strengthen relationships across community clinics and AICs. Develop new business and expand partnerships while collaborating with key decision-makers in a complex healthcare market. T...
2 weeks ago
Director of Sales Execution - Midwest
$135K - $160K *
Lead a high-performing, multi-state sales execution team of 200+, driving strategy to execution across markets. Collaborate with partners to enhance performance, while developing future sales leaders...
Reposted 2 weeks ago
$200K - $300K *
Drive success by managing sales within your district, leading a high-performing team, executing strategies, and fostering partner relationships for growth and brand visibility...
Reposted 3 days ago
Northeast Regional Sales Manager - Contract Furniture
$120K - $130K *
Grow your career with a dynamic role driving regional sales and dealer engagement. Collaborate with independent reps to develop strategies, enhance relationships, and deliver exceptional customer expe...
3 weeks ago
Outside Sales Consultant / Business Performance Advisor
$95K - $110K *
Empower businesses by providing tailored HR solutions, leveraging your consultative sales skills to build lasting relationships and drive growth in a supportive, dynamic environment focused on client...
1 week ago
VP, Strategic Business Partner - Business Development
$180K - $240K *
Lead strategic business initiatives by building relationships with senior executives to drive revenue growth in life sciences. Develop actionable plans to identify opportunities and enhance market pos...
Reposted 2 weeks ago
Director, Commercial Planning & Excellence
$170K - $180K *
Lead the strategic execution of commercial planning and sales coverage, aligning cross-functional teams to drive profitable growth. Oversee territory design, customer segmentation, and annual planning...
4 weeks ago
Sr. Strategic Sales Manager (Ohio)
$112K - $143K *
Join us to drive growth by identifying and securing new B2B payment opportunities. Leverage your consultative sales skills to manage the full sales cycle, build client relationships, and optimize our...
4 weeks ago
Head of National Strategic Accounts
$250K - $300K *
Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...
Reposted 2 weeks ago
Senior Vice President and General Manager - Solutions Management
$180K - $220K *
Join a team that's driving strategic growth and profitability in healthcare solutions. Lead cross-functional initiatives, own P&L, and ensure client success while shaping market strategy and solution...
Reposted yesterday
$185K - $400K *
Transform the retirement landscape by leading a dynamic sales team, driving growth, and enhancing client relationships in the Defined Contribution market. Your strategic vision will shape the future o...
1 week ago
Vice President- Advanced Technical Services
$250K - $500K *
Transform delivery services by owning P&L and driving strategy across complex networks and AI solutions. Lead a large-scale team, ensuring quality and efficiency while enhancing customer satisfaction...
Reposted 4 weeks ago
Senior Product Development Leader
$110K - $130K *
Unlock potential by leading commercialization and scale-up of innovative food products. Utilize your expertise in meat science and hands-on leadership to transform product designs into reliable manufa...
2 weeks ago
Director of Strategic Accounts, Central U.S.
$135K - $160K *
The Director of Strategic Accounts is responsible for developing and closing business with Motive's largest prospects, primarily targeting Fortune 500 companies. This role involves building relationsh...
Reposted 2 weeks ago
$230K - $275K *
Join a team that's redefining B2B sales by leading and mentoring a high-performing regional team while driving significant revenue growth and building a vibrant sales culture in a rapidly scaling envi...
Reposted 4 days ago
$128K - $192K *
Unlock potential by driving new business growth through actionable health intelligence. Build relationships, identify client needs, and showcase solutions to enhance employee wellbeing and manage heal...
5 days ago
Vice President, Medicare Partnerships
$150K *
Lead the charge in driving Medicare partnerships, enhancing contract value, and achieving growth targets through strategic sales initiatives and relationship management with health plans...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.