Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$312K - $402K *

Lead the global product strategy from concept to launch, ensuring cross-functional alignment and maximizing asset value throughout its lifecycle. Collaborate with diverse teams to drive successful com...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Pioneer capital relationships across M&A and investment vehicles. Drive fundraising efforts and educate investors on private markets. Build a wealth channel from the ground up while collaborating with...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Accelerate capital relationships by building networks with allocators and family offices. Drive fund raises and support M&A mandates while educating investors on private market structures. Own your im...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Drive revenue growth by managing key customer relationships and delivering accurate forecasts. Collaborate with teams to support product development and ensure compliance with industry standards while...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion the full sales cycle for top enterprise accounts, utilizing a consultative approach to solve complex challenges. Drive impactful relationships with stakeholders, and navigate lengthy processe...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Elevate travel businesses by leading the full sales cycle, addressing complex financial challenges in cross-border payments. Build relationships, improve customer outcomes, and collaborate with intern...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$163K - $224K *

Drive strategic planning and execution of acquisitions/divestitures, ensuring seamless integration and value creation across teams. Collaborate cross-functionally to manage milestones, risks, and comm...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $175K *

Lead transformative insurance program initiatives, overseeing technology enhancements and operational workflows. Collaborate across teams to drive project management and ensure compliance, while optim...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $145K *

Unlock your potential as a strategic partner in business development, driving revenue through VARs and resellers. Collaborate with sales teams to enhance partner engagement and pipeline creation, ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$175K - $219K *

Help us elevate Field Medical operations by optimizing processes, enhancing communication, and driving strategic initiatives to ensure effective engagement and alignment across teams in a dynamic heal...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Join a dynamic team to define and execute impactful product strategies that enhance customer solutions in the financial sector. Lead complex partnerships and drive product expansion, shaping the futur...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $170K *

Shape the future of healthcare market strategies by analyzing trends, defining growth initiatives, and collaborating cross-functionally to drive innovation in life science and medical services. Lead m...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $136K *

Drive the governance and operational excellence of enterprise Master Data, ensuring data quality and compliance across multiple domains. Collaborate with stakeholders to implement standards and facili...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $120K *

Join a dynamic team to drive sales of AI solutions to community banks and credit unions. Manage the full sales cycle, from pipeline generation to closing, while exceeding quotas in a fast-paced, high...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $300K *

Lead the charge in driving enterprise sales by collaborating with Microsoft teams to identify and capitalize on AVD opportunities. Leverage your expertise in VDI and EUC technologies to foster relatio...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Drive business growth by executing strategic sales plans and building client relationships. Leverage industry tools to identify prospects, present solutions, and negotiate contracts while collaboratin...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $165K *

Empower clients by leveraging technical expertise to demonstrate product value, cultivate relationships, and drive sales success through effective communication and strategic engagement with stakehold...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock your potential by driving sales of innovative pulmonary solutions. Collaborate with diverse stakeholders to enhance patient care and achieve sales targets in a dynamic healthcare environment. J...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Drive impactful program management by leading cross-functional initiatives, ensuring alignment with strategic goals, and delivering measurable results in a dynamic environment. Collaborate effectively...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $100K *

Empower People Operations by optimizing processes across the employee lifecycle. Collaborate cross-functionally to enhance efficiency, drive improvements, and maintain high-quality HR services while s...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$182K - $247K *

Join a team that's redefining operational excellence in healthcare. Lead a diverse team to streamline utilization management processes, enhance technology integration, and drive measurable improvement...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$97K - $146K *

Join a team that's driving operational excellence in merchandising strategy. Collaborate cross-functionally to enhance market share growth and optimize performance through data-driven insights and inn...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$170K - $220K *

Accelerate your career by driving sales growth through strategic partnerships and innovative solutions in the cloud computing space. Collaborate with teams to achieve targets and enhance customer sati...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's driving financial excellence by managing revenue accounting activities, ensuring compliance with ASC 606, and leveraging advanced analytics to enhance reporting and operational effi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.