Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
$150K - $200K *
Accelerate progress at the forefront of product innovation, leading a team to drive strategy and customer experience for a key transaction management platform while embedding AI to enhance efficiency...
1 week ago
$124K - $156K *
Shape the future of AI Services by owning product strategy and execution. Collaborate with engineering teams to define agentic capabilities, drive tool strategies, and establish AI quality standards t...
2 weeks ago
$190K - $200K *
Elevate your career by driving sales strategy and execution for a dynamic SaaS portfolio. Lead a high-performing team to achieve revenue growth, optimize pipeline management, and enhance customer acqu...
1 week ago
Director, Business Transitions
$225K - $250K *
Engage with business owners navigating M&A transactions, providing integrated planning and support. Collaborate with deal teams to ensure seamless transitions and optimize after-tax outcomes during cr...
2 days ago
$250K - $300K *
Lead a dynamic sales team to drive growth in Application Lifecycle Management (ALM) software. Strategize and implement sales processes, analyze market trends, and cultivate key client relationships to...
Reposted yesterday
Regional Sales Director - St. Louis
$180K - $215K *
Tackle the challenge of launching a groundbreaking product by leading a high-performing sales team, driving regional execution, and fostering key customer relationships in a dynamic, fast-paced enviro...
1 week ago
Install Base Sales Manager - West
$110K - $130K *
Drive growth and maximize customer value by enhancing software adoption, expanding service revenue, and fostering long-term relationships within the installed base of clinical technologies in a dynami...
Today
Account Executive, HME Provider Sales
$80K - $100K *
Join a team that's driving growth by acquiring new customers and enhancing revenue through innovative solutions. Manage the full sales cycle while collaborating with cross-functional teams to ensure e...
6 days ago
$91K - $122K *
Empower and lead a high-performing sales team to exceed targets, fostering strategic relationships and guiding consultative sales strategies that highlight key market differentiators for sustained gro...
Reposted 4 days ago
$155K - $185K *
Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...
3 days ago
Vice President, Growth (Pharma)
$150K - $200K *
Join a dynamic team to drive growth in the pharmaceutical sector, leveraging your expertise to build relationships, win new business, and deliver impactful solutions that enhance brand performance and...
2 days ago
$80K - $95K *
Elevate your sales career by driving full-cycle sales in a dynamic environment. Leverage AI tools and consultative frameworks to engage high-growth organizations, exceed targets, and enhance your prod...
5 days ago
$160K - $185K *
Join a team that's redefining the SaaS landscape by driving strategic growth and closing high-value deals. Engage with senior leaders, develop a robust pipeline, and collaborate cross-functionally to...
Reposted 2 days ago
$86K - $135K *
Accelerate progress at driving sales growth by managing key accounts, pursuing new opportunities, and collaborating with cross-functional teams to deliver exceptional customer results in the specialty...
4 days ago
$135K - $170K *
Optimize your sales career by managing the full sales cycle for a leading engineering software. Leverage your technical expertise to drive revenue growth and deliver impactful solutions to industrial...
2 weeks ago
Sales Manager Specialty Fluids
$100K - $120K *
Empower your career as a Sales Manager in the Specialty Fluids sector, driving growth through strategic account management and lead generation while collaborating with diverse teams across North Ameri...
Reposted 5 days ago
$75K - $131K *
Transform customer engagement and drive strategic growth by identifying revenue opportunities, cultivating relationships, and collaborating with cross-functional teams to enhance product positioning a...
3 weeks ago
$72K - $192K *
Join a team that's dedicated to enhancing client relationships in healthcare. As a trusted advisor, you'll guide clients through workflows, drive feature adoption, and develop strategic plans to maxim...
4 days ago
Account executive-North Central US
$110K - $130K *
Drive growth by building and expanding enterprise pipelines through strategic outbound efforts and executive networking. Collaborate cross-functionally to secure high-value deals and establish long-te...
5 days ago
RVP, Enterprise Sales - Northeast
$231K - $363K *
Grow your career with a dynamic sales role focused on building enterprise partnerships. Drive impactful healthcare solutions by engaging with HR leaders and managing the full sales cycle across the No...
3 weeks ago
$160K - $200K *
Drive operational excellence by leading a global team to enhance post-sale services, optimize processes, and ensure customer satisfaction. Collaborate across departments to implement scalable solution...
1 week ago
$100K - $120K *
Join a team that's transforming women's health by driving sales in OB/GYN and maternal-fetal medicine. You'll manage the full sales cycle, leveraging existing relationships to expand our reach and ens...
3 weeks ago
Account Executive, Midwest ECM
$80K - $95K *
Unlock potential by driving growth in our Enterprise Content Management business. Engage with diverse stakeholders, navigate complex sales cycles, and expand client relationships across the Midwest wh...
5 days ago
$120K - $150K *
Drive the success of a dynamic sales team by managing daily operations, coaching, and ensuring pipeline health. Collaborate with leadership to translate strategy into actionable priorities while foste...
2 weeks ago
Vice President, Global Supply Chain
$272K - $340K *
Lead the charge in shaping a global supply chain strategy that ensures seamless delivery of clinical and commercial products. Build a high-performing team and foster partnerships to meet regulatory st...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.