Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$167K - $245K *

Accelerate IT innovation by leading operations and engineering teams that enhance productivity and security for a 500+ remote workforce, while embedding AI and automation into core processes for optim...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Information Technology

$40K - $200K *

Join a dynamic team to drive business growth through consultative sales, building lasting client relationships, and delivering innovative payment solutions. This role offers uncapped earnings and oppo...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$210K - $250K *

Shape the future of patient access by leading integrated strategies that enhance customer engagement and optimize portfolio performance across diverse healthcare channels, driving sustainable growth a...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $240K *

Reimagine operational excellence as you lead infrastructure and production teams, ensuring reliability and innovation in technology delivery. Drive process improvements and foster collaboration to mee...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $125K *

Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Transportation

$150K - $180K *

Transform healthcare operations by leading a dedicated team in a critical illness recovery hospital. Drive quality care, employee engagement, and strategic initiatives while ensuring compliance and op...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$141K - $189K *

Join a dynamic team to drive strategic growth within the Department of Veterans Affairs, leveraging your expertise to build relationships, execute account strategies, and navigate complex procurement...

RemoteRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Join us in driving growth by acquiring new customers and expanding existing relationships. This field-oriented role requires a motivated hunter skilled in building pipelines and fostering executive co...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Develop and execute innovative product strategies for a global Oil-Flooded compressor portfolio, driving profitable growth through customer insights and cross-functional collaboration to enhance marke...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join us to lead transformational sales in digital operations, driving complex solutions across cybersecurity and manufacturing. Collaborate with stakeholders to unlock value and accelerate customer ou...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Transform the sales landscape by providing expert technical support and product demonstrations. Collaborate cross-functionally to address customer needs and enhance internal training, driving success...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Shape the future of commercial sales by cultivating relationships with national accounts, driving revenue growth, and leading strategic initiatives to exceed market share goals while ensuring customer...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Accelerate your career by leading sales growth and strategic partnerships in the Executive Benefits sector. Drive revenue, expand market presence, and enhance employee protection through innovative id...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$66K - $127K *

Shape the future of pharmaceutical marketing by leading PRC operations, ensuring compliance, and driving process improvements. Collaborate cross-functionally to enhance promotional material review and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $135K *

Join a team that's driving innovation and operational excellence in digital services. This role involves project management, cross-functional collaboration, and strategic execution to ensure successfu...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate customer success in the Americas by leading a growing team of CSMs. Drive adoption, value realization, and customer health while shaping playbooks and strategies for scalable growth. Collabora...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$109K - $164K *

Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in shaping Stedi's litigation strategy, driving affirmative disputes and regulatory actions to protect and expand our operational freedom in the healthcare sector. Collaborate with lea...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $100K *

Engage with customers and drive revenue growth by managing accounts and pursuing new business opportunities. Utilize consultative selling to achieve sales targets while collaborating with internal tea...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Accelerate revenue growth by driving strategic partnerships and sales initiatives. Own a quota, cultivate executive relationships, and implement market strategies to position the organization as a lea...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $120K *

Lead the charge in building and scaling a high-performing sales team in the residential roofing industry. Drive revenue growth, develop top talent, and create a culture of accountability and results i...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Lead and transform casino operations by directing activities across slots and table games. Ensure compliance, optimize performance, and enhance guest satisfaction while developing strategic goals for...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$110K - $130K *

Drive the sales process from prospecting to close, engaging healthcare leaders to showcase AI solutions that enhance patient access and operational efficiency. Join a dynamic team focused on exceeding...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Transform sales leadership by building and guiding a high-performing team to drive growth and retention in the AMER region, collaborating across departments to execute strategic initiatives and enhanc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leading the full sales cycle, building executive relationships, and driving business transformation across industries. Collaborate with teams to innovate sales processes and ensure...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.