Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$95K - $115K *

Join our dynamic team as a Finance Manager, where you'll lead financial analysis, develop models, and present insights to senior leadership, driving growth and accuracy in financial reporting across t...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $95K *

Shape the future of financial solutions by leveraging your technical expertise and consultative skills. Collaborate with clients and internal teams to design impactful solutions that drive business su...

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$172K - $223K *

Champion operational excellence as a strategic leader, driving performance and financial results across the PacWest Region while ensuring safety, quality, and compliance in a mission-driven environmen...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$160K - $200K *

Unlock your potential as a strategic leader driving growth through innovative marketing strategies. Collaborate with teams to enhance demand generation and optimize performance, ensuring alignment wit...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$90K - $110K *

Engage with clients, driving success in digital campaign execution. Become an expert in programmatic advertising processes, enhancing customer satisfaction through effective communication and collabor...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Accelerate progress at driving new business growth in IP services by engaging corporate IP departments and legal teams. Leverage consultative selling to expand accounts and build lasting relationships...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$160K - $200K *

Shape and drive commercial strategies to enhance revenue growth and client relationships across diverse consumer brand sectors. Collaborate with teams to ensure client satisfaction while identifying n...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Media

$134K - $216K *

Lead the charge in driving sales strategies and operations for a premier MedTech portfolio. Oversee a diverse sales team, enhance customer relationships, and achieve growth targets while ensuring comp...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$250K - $290K *

Elevate your career by leading a high-performing engineering team, driving strategy and innovation in web3 technologies. Shape the future of decentralized systems while ensuring top-tier security and...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$272K - $374K *

Empower our sales team to drive revenue growth by leading strategic engagements with Federal Systems Integrators. Utilize your expertise to craft account plans, build relationships, and navigate compl...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Transform operations by leading underground storage activities, optimizing resource management, and ensuring compliance with safety standards. Drive team performance and enhance facility reliability w...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Contribute to a dynamic legal team by providing expert counsel on construction contracts, compliance, and risk management. Collaborate with leadership to navigate legal challenges and ensure operation...

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$130K - $165K *

Drive strategic growth by acquiring new logos and expanding partnerships within large health systems. Navigate complex sales cycles, build executive relationships, and enhance enterprise value through...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Empower a high-performing sales team to drive revenue growth and exceed targets. Collaborate in a dynamic environment, coaching and inspiring talent while executing strategic sales plans for a global...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$88K - $105K *

Lead the management of pharmaceutical programs, ensuring client satisfaction and operational excellence. Oversee daily activities, supervise staff, and drive strategic planning while maintaining stron...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive new-client acquisition by managing the full sales cycle, from prospecting to contract signing. Collaborate with marketing and commercial teams to deliver tailored solutions and build executive r...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$270K - $340K *

Unlock potential by driving sales for innovative healthcare compliance solutions. Own the full sales cycle with health plans, transforming initial conversations into lasting partnerships while shaping...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform regulatory strategies for rare disease and cardio-pulmonary drug-device programs. Collaborate with cross-functional teams to ensure compliance and drive successful submissions globally, supp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $185K *

Help us drive growth by partnering with sales and business teams to streamline complex transactions. This role offers a unique opportunity to influence revenue operations and engage directly with clie...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$180K - $195K *

Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Join a team that's driving growth by identifying and closing new client opportunities in experiential marketing. Leverage your network and expertise to engage youth and Gen Z through innovative campai...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$150K - $200K *

Grow your career with a dynamic role focused on driving new business in the healthcare provider space. Leverage your sales expertise to exceed quotas, engage decision-makers, and collaborate with inte...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.