Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$147K - $217K *

Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...

RemoteRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$160K - $200K *

Join a team that's driving growth in the dynamic SaaS landscape. Lead strategic sales initiatives, manage top-tier talent, and engage with Fortune 500 clients to deliver impactful solutions that prope...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$162K - $238K *

Design and optimize R&D operations to enhance organizational effectiveness through data-driven insights, collaboration, and governance. Partner cross-functionally to drive continuous improvement and e...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$215K - $250K *

Pioneer your career by leading a dynamic sales team focused on Labor and Public Sector markets. Drive growth, mentor talent, and execute strategic initiatives to exceed revenue goals while building im...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$94K - $179K *

Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leading strategic account management initiatives, driving customer satisfaction and revenue growth through effective relationship building and expansion strategies in a dynamic ent...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$185K - $231K *

Unlock potential by leading regional service delivery, driving growth and operational excellence across multiple territories. Collaborate with diverse teams to enhance customer satisfaction and optimi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$160K - $200K *

Shape the future of product strategy by leading a high-performing team, driving innovation, and ensuring alignment across operations and technology to deliver exceptional customer value and measurable...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Shape high-impact growth in retail partnerships by overseeing field operations, driving application volume, and enhancing point-of-sale conversion rates. Collaborate with teams to optimize strategies...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Transform business lending by building lasting relationships and driving growth. Leverage your expertise in C&I and real estate lending to expand community presence and support members in achieving th...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Empower business growth by fostering relationships and expanding lending opportunities. Leverage your expertise in C&I and real estate lending to enhance community engagement and drive portfolio succe...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leading innovative demand generation strategies that drive pipeline growth and market engagement. Collaborate across departments to optimize campaigns and mentor teams, ensuring al...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $240K *

Accelerate progress at strategic partnerships in the NAMER region by identifying, onboarding, and managing key partners. Drive revenue growth through collaboration, enablement, and relationship manage...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in expanding market presence for cutting-edge hospitality tech solutions across North America. Drive new business sales, build relationships, and collaborate with teams to achieve reve...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$110K - $130K *

Join a team that's driving innovation in cybersecurity by leveraging your technical expertise to support enterprise sales. Engage with top-tier clients, guiding them through complex evaluations and de...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $329K *

Drive operational excellence as you lead sales operations and business planning teams, translating data into strategic decisions that enhance revenue outcomes and foster collaboration across functions...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Discover a pivotal leadership role in IT financial management, vendor governance, and technology optimization. Collaborate across departments to ensure technology investments yield value while managin...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $112K *

Drive the success of a dynamic SDR team by shaping outbound sales strategies, mentoring talent, and optimizing lead generation processes. Collaborate with leadership to build a high-performing team th...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$109K - $129K *

Take ownership of product development in a dynamic, cross-functional team. Drive AI-assisted innovation from problem framing to launch, focusing on customer outcomes and strategic impact in a hyper-ag...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $155K *

Champion business development and growth of custom adhesive solutions across North America, focusing on the Bus, Truck, Rail, and Specialty Vehicle markets. Drive customer acquisition and strategic ac...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$285K - $385K *

Champion transformative People technology and operations, driving AI and automation to enhance employee experiences. Lead strategic initiatives, optimize systems, and ensure data integrity while foste...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$317K - $375K *

Take ownership of the pharmacy business, driving strategy, growth, and performance. Lead a skilled team, manage P&L, and ensure compliance while enhancing member experiences in a regulated environment...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K *

Transform your career by driving new business in public safety. Collaborate with internal teams to build relationships and innovate solutions for Fire, EMS, and Emergency Management agencies in a dyna...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join us to drive new customer acquisition for ERP solutions in discrete manufacturing. This full-cycle sales role requires building relationships, managing complex sales processes, and achieving reven...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Join a team that's dedicated to managing and expanding industrial water treatment accounts across Ohio and Indiana. Leverage your technical expertise and consultative selling skills to drive growth an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.