Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.
Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.
Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.
Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.
$116K - $147K *
Lead the charge in designing and analyzing information systems to meet user needs while ensuring compliance with the organization’s architecture. Collaborate with technical teams to develop effective...
Reposted 1 week ago
Lead Implementation Consultant
$100K - $120K *
Join a team that's pivotal in implementing strategic solutions for Fortune 500 clients. You'll drive key project initiatives, ensuring effective change management and superior customer adoption for wo...
Reposted yesterday
Principal Clinician - Revenue Cycle Management (RCM)
$120K - $150K *
Lead the charge in advancing clinical revenue cycle management initiatives, ensuring accurate documentation and coding while driving performance improvements across diverse stakeholders to enhance rev...
Reposted 2 weeks ago
$145K - $150K *
Join a team that's redefining pay equity solutions. Drive sales cycles, engage with enterprise clients, and leverage innovative tech to ensure fair compensation practices. Collaborate with diverse sta...
Today
$80K - $95K *
Drive growth by leveraging your expertise in technical sales while collaborating with diverse teams to enhance product offerings and engage end users across key industries. Shape market dynamics throu...
2 weeks ago
Senior Director, HR Business Partner (GTM)
$160K - $190K *
Join a team that serves as the dedicated business partner for GTM functions, providing strategic leadership and trusted advisory to executive leaders while driving talent, performance, and organizatio...
3 weeks ago
$85K - $128K *
Drive impactful financial narratives by translating technical data into compelling ROI stories. Collaborate with IT and finance leaders to optimize value frameworks and enhance decision-making for glo...
2 days ago
$110K - $130K *
Elevate strategic insights and performance reporting for pharmaceutical media. Collaborate across teams, leveraging data analytics and AI solutions to enhance growth and client outcomes in a fast-pace...
Reposted 1 week ago
Registered Nurse - Levine Cancer Oncology Infusion
$73K - $110K *
Empower patient care by utilizing your nursing expertise to assess, plan, and implement effective treatment strategies. Collaborate with a dedicated team to enhance outcomes and engage patients throug...
1 week ago
$80K - $95K *
Lead the charge in driving new business development through full sales cycle management, establishing relationships, and exceeding revenue targets by leveraging consultative selling and effective pipe...
Reposted 1 week ago
$125K - $150K *
Champion business development to foster strategic partnerships in biotech, leveraging technical expertise and market insights to drive multi-million dollar enterprise revenue while shaping innovative...
2 weeks ago
Procurement Initiatives and Compliance Lead
$143K - $196K *
Lead the charge in driving procurement compliance and strategic initiatives, collaborating across functions to optimize processes and ensure adherence to regulations while supporting business goals an...
Today
Registered Nurse (RN) - Levine Cancer GU Infusion Clinic
$73K - $110K *
Unlock your potential as a compassionate RN, coordinating comprehensive patient care in a collaborative outpatient clinic focused on genitourinary and neurological cancers. Ensure safe, therapeutic ca...
3 weeks ago
$175K - $210K *
Accelerate growth by leading strategic alliances, enhancing partner productivity, and managing Alliance Directors to meet performance goals while driving collaboration across business units for succes...
3 weeks ago
$115K - $127K *
Elevate your career by monitoring oncology clinical trials, ensuring compliance, and supporting investigative sites. This role requires strong expertise in clinical research and a passion for advancin...
5 days ago
$110K - $130K *
Lead the design and implementation of advanced automation systems, ensuring high-performance processes and compliance with regulatory standards while mentoring junior engineers and managing complex pr...
1 week ago
$54K - $145K *
Transform healthcare relationships by managing provider networks, enhancing performance, and collaborating with stakeholders to ensure quality care and network expansion. Play a key role in driving st...
5 days ago
Procurement Senior Specialist - Multi-Commodity
$88K - $105K *
Unlock procurement excellence by leading strategic sourcing and supplier management across diverse indirect spend categories, ensuring alignment with business needs and compliance while driving cost o...
Today
Procurement Senior Specialist - Multi-Commodity
$88K - $105K *
Join a team that's enhancing procurement operations by driving strategic sourcing and supplier management across varying indirect spend categories to optimize costs and improve compliance while collab...
Reposted 5 days ago
$80K - $95K *
Lead a team in assembling complex aerostructures, ensuring quality and efficiency while interfacing with engineering and management to meet production goals and customer requirements...
6 days ago
$71K - $120K *
Help us drive strategic HR initiatives by advising clients across the full employee lifecycle, ensuring compliance, and fostering strong relationships to enhance workforce effectiveness and alignment...
3 weeks ago
$112K - $165K *
Shape the future of HR compliance by leading initiatives that ensure alignment with employment laws and internal policies. Collaborate with stakeholders to identify risks, enhance practices, and promo...
3 days ago
$112K - $165K *
Optimize firm-wide HR compliance by enhancing policies, procedures, and training. Collaborate with leadership to manage risks and promote adherence to employment laws while ensuring a legally complian...
2 weeks ago
$125K - $187K *
Analyze and negotiate complex contracts in healthcare, leveraging data-driven insights to enhance outcomes and drive strategic initiatives. Collaborate with stakeholders to optimize processes and fost...
2 weeks ago
$100K - $150K *
Build strategic partnerships and drive revenue growth by managing high-potential accounts. Collaborate with internal teams to enhance partner engagement and achieve production targets while fostering...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.
Which North Carolina cities have professional job opportunities?
Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.
Does Ladders list jobs paying $100,000 or more?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.
How can I search for jobs in North Carolina?
Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.