Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.
Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.
Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.
Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.
Manager, Business Development, National Center for Clinical Trials (NCCT)
$114K - $171K *
Join a team that's driving growth in clinical trials by identifying and securing partnerships. Collaborate with cross-functional leaders to enhance visibility and expand opportunities, ensuring seamle...
1 week ago
$185K - $205K *
Elevate your career as a Product Manager, guiding AI/ML software development. This role involves creating strategic roadmaps, collaborating with cross-functional teams, and driving impactful business...
Reposted 2 weeks ago
Director, Market Development (Chicago)
$120K - $150K *
Join a team committed to driving growth through strategic relationships with healthcare organizations. Play a key role in delivering innovative workforce solutions that address complex challenges, enh...
2 weeks ago
$120K - $140K *
Optimize software solutions as a Senior .NET Developer, collaborating with a dynamic engineering team to design, develop, and maintain applications for the electrical utility sector, while supporting...
Today
Resource Registered Nurse - Medical Group Float Pool
$79K - $118K *
Join a dynamic nursing team dedicated to delivering exceptional patient care across multiple facilities. Engage in quality initiatives, collaborate with healthcare professionals, and uphold safety sta...
6 days ago
$140K - $165K *
Join a team that's dedicated to proactively identifying and mitigating insider threats. This role involves investigating potential data breaches and enhancing threat detection capabilities to protect...
Today
$80K - $95K *
Empower our analyst relations program by managing evaluations, timelines, and coordination. Collaborate with stakeholders to ensure accurate, timely engagement and support market insights for strategi...
Reposted 1 week ago
Sr. Employee Relations Consultant
$82K - $92K *
Empower a positive workplace by providing strategic consultation and resolving complex employee relations issues. Collaborate with staff and management to ensure compliance with employment laws and fo...
1 week ago
$110K - $135K *
Inspire growth by managing the end-to-end proposal process, crafting compelling responses, and collaborating with cross-functional teams to enhance strategic alignment and efficiency in a fast-paced e...
4 days ago
$100K - $120K *
Lead the charge in transforming the construction industry by driving sales of AI-powered preconstruction tools. Own the full sales cycle and partner with teams to maximize growth and enhance bidding e...
Reposted 2 weeks ago
$106K - $159K *
Join a team that's leading high-quality care in a newly expanded trauma unit. Oversee clinical and operational functions for a diverse patient group, fostering a safe environment while promoting staff...
Reposted 2 weeks ago
Director, Talent - Talent Management
$110K - $120K *
Accelerate progress at the forefront of Talent Management by driving performance, fostering employee relations, and optimizing strategic initiatives in a dynamic environment. Lead cross-functional pro...
1 week ago
$86K - $117K *
Join a team that's redefining accounting through automation and AI. Own revenue recognition, enhance controls, and collaborate with cross-functional teams while driving innovative solutions and ensuri...
3 weeks ago
$142K - $195K *
Shape the compliance function for a fast-growing commercial lending program, ensuring adherence to AML, BSA, KYC, and sanctions regulations across multi-geographies. Lead policy development and direct...
Reposted 2 weeks ago
$80K - $95K *
Lead HR initiatives to drive local business strategies, foster employee relations, and ensure compliance. Build partnerships with management and develop programs that enhance workforce engagement and...
2 weeks ago
$80K - $95K *
Empower a vibrant HR culture by leading comprehensive employee relations strategies, driving talent management initiatives, and ensuring compliance across HR operations to support business objectives...
2 weeks ago
$150K - $250K *
Lead enterprise growth efforts by aligning marketing objectives with our advanced AI tools. Collaborate with senior leadership to develop impactful marketing roadmaps that foster long-term client succ...
Reposted 1 week ago
Clinical Supervisor - Home Health
$91K - $137K *
Transform patient care by overseeing clinical operations and guiding staff to enhance healthcare delivery, while ensuring compliance with regulations and promoting quality control in a dynamic home he...
Reposted 2 weeks ago
Frontend Engineer, Ads Campaign Manager
$164K - $229K *
Unlock your potential as a mid-level frontend engineer, leading projects that enhance advertiser experiences. Collaborate with diverse teams, build intuitive tools, and drive performance while making...
2 weeks ago
Registered Nurse (RN) - 10T Med/Tele
$79K - $118K *
Manage comprehensive patient care in a dynamic medical telemetry unit. Collaborate with a skilled team to deliver high-quality nursing using evidence-based practices while ensuring a safe and therapeu...
2 weeks ago
$170K - $253K *
Unlock potential by designing and developing innovative storage solutions in a dynamic team environment. Contribute to advanced features of a robust storage platform serving critical applications acro...
Reposted 5 days ago
$170K - $253K *
Optimize cloud-based solutions by leading the software development lifecycle. Collaborate with engineering teams to solve complex problems and enhance system performance while mentoring junior develop...
4 weeks ago
$100K - $149K *
Drive operational excellence by providing expert support for cloud-hosted open-source technologies. Collaborate with cross-functional teams to resolve incidents and enhance system performance while en...
Reposted 5 days ago
Registered Nurse (RN), Internal Medicine
$73K - $110K *
Join a team that's committed to enhancing patient care through evidence-based practices. As a key player, you will monitor patient conditions, collaborate with care teams, and foster a culture of safe...
Reposted 2 weeks ago
Senior Manager, Compliance Officer
$105K - $135K *
Join a team that's dedicated to ensuring compliance and risk management excellence. This role involves overseeing risk assessments, developing policies, and implementing corrective actions to maintain...
3 days ago
What types of $100K+ jobs can I find in North Carolina?
Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.
Which North Carolina cities have professional job opportunities?
Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.
Does Ladders list jobs paying $100,000 or more?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.
How can I search for jobs in North Carolina?
Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.