Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

Remote
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Compensation
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$138K - $183K *

Empower analytical excellence by leading method transfers and managing a skilled team in a fast-paced environment, ensuring compliance with rigorous standards to support cutting-edge biopharmaceutical...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive product vision and growth at the intersection of AI and science. Leverage strategic and technical expertise to define, prioritize, and enhance cutting-edge product capabilities while collaborati...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $150K *

Join a dynamic team leading innovative projects in the field of hydrogen technologies. Drive the execution of programs, foster collaboration, and inspire a safe, engaging work environment to enhance o...

Chalk River, ONIn-Person

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$90K - $100K *

Drive project management for protein expression services, coordinating teams to deliver client-focused solutions. Enhance service offerings by understanding market trends while fostering collaboration...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$111K - $151K *

Take ownership of drug product process engineering, providing technical leadership and ensuring successful commercialization and lifecycle management across cross-functional teams and global manufactu...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$75K - $90K *

Join a team that drives scientific innovation through advanced chemical expertise. Collaborate on product development and process improvements while ensuring rigorous compliance and high research stan...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$174K - $252K *

Unlock potential by leading cutting-edge research in AI and machine learning. Collaborate with diverse teams to create innovative solutions, conduct experiments, and publish impactful findings, shapin...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join our team to empower peptide manufacturing excellence through technical leadership, process optimization, and cross-functional collaboration, driving improvements in yield, efficiency, and complia...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $170K *

Lead the charge in executing oncology clinical trials, ensuring smooth operations by collaborating with CROs and trial sites under senior guidance, while driving feasibility, site selection, and close...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $230K *

Lead the charge in biostatistical strategies for clinical trials, ensuring high-quality data analysis and regulatory compliance. Collaborate across teams to drive successful drug development initiativ...

US-AnywhereRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $100K *

Redefine formulation processes by optimizing dietary supplement formulations, providing hands-on technical support across R&D and manufacturing to ensure compliance, efficiency, and innovation in a fa...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that excels in Pharmacovigilance project management, ensuring client satisfaction through effective communication, meticulous planning, and quality project delivery. Enhance your leadershi...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's dedicated to delivering exceptional pharmacovigilance services while managing client relationships and overseeing project scope, milestones, and reporting, ensuring satisfaction and...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$98K - $126K *

Lead the charge in optimizing procurement and planning of materials, driving cost-reduction initiatives and enhancing supplier performance within a dynamic biotech environment to ensure seamless produ...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion the design and execution of electrical systems for high-tech facilities, ensuring high-quality deliverables through collaboration, technical expertise, and project management across diverse e...

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$92K - $110K *

Design and execute comprehensive solutions for engine line projects, leading the development and specification of die casting and assembly equipment while managing project timelines and collaborating...

Alliston, ONIn-Person

3 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$156K - $253K *

Lead contractor safety initiatives across major capital projects, ensuring compliance with safety protocols and fostering a strong safety culture. Collaborate with project managers and HSE teams to en...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower the team by planning and executing electrical engineering projects. Engage in design, testing, and maintenance of control systems while providing leadership and expertise, ensuring success acr...

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive impactful quality assurance and pilot plant support, ensuring safe and efficient scale-up from lab to production. Collaborate across teams to enhance processes and maintain exceptional standards...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$113K - $151K *

Drive innovative product strategies and manage proactive lifecycle improvements while collaborating across functions to deliver market-leading solutions that enhance customer success and satisfaction...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$204K - $270K *

Elevate your career by leading the design and development of cutting-edge production systems integrating Generative AI and agentic workflows. Collaborate with diverse teams to drive engineering excell...

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$204K - $270K *

Transform the design and delivery of innovative AI-powered systems, collaborating across teams to drive architecture standards, mentor engineering talent, and communicate effectively with executives t...

4 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$105K - $130K *

Lead the charge in quality control management, ensuring compliance with regulations while developing a high-performing microbiology team. Oversee lab operations, enhance testing methods, and collabora...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Elevate product strategies by driving portfolio decisions, market insights, and lifecycle management, while partnering with cross-functional teams to deliver innovative solutions in a competitive land...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.