Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$110K - $130K *
Drive innovative solutions by leveraging data analytics and strategic counsel to enhance client performance. Collaborate with high-performing teams to deliver tailored insights for transformational ev...
1 week ago
Principal Sales Solutions Consultant
$160K - $195K *
Engage with healthcare payer clients to architect integrated solutions, driving revenue growth through strategic discovery, technical leadership, and value engineering. Collaborate across teams to del...
4 days ago
Director, Supply Chain Strategy & Excellence
$235K - $270K *
Join a dynamic team to lead transformative improvements in global supply chain operations, focusing on logistics excellence and strategic initiatives that enhance service, cost efficiency, and operati...
Reposted 2 days ago
Senior Director Enterprise Services - North Carolina
$159K - $218K *
Drive strategic growth by leading national accounts and fostering executive relationships. Collaborate across teams to enhance customer engagement and market share, while executing comprehensive accou...
2 weeks ago
Associate Director, Insurance Compliance
$120K - $145K *
Drive compliance excellence by leading insurance operations, optimizing processes, and mitigating risks across a commercial loan servicing portfolio while ensuring adherence to regulatory and investor...
2 days ago
$170K - $195K *
Engage in strategic account acquisition for our Legal Technologies sector, focusing on sourcing, qualifying, and closing new enterprise accounts. Drive revenue growth through complex sales cycles whil...
1 week ago
$187K - $257K *
Empower transformation initiatives by leading enterprise projects, managing stakeholder relationships, and driving strategic outcomes. Collaborate with diverse teams to define program strategies and e...
Yesterday
$120K - $150K *
Lead the charge in building long-term customer relationships while optimizing operations. As a Business Manager, you'll drive strategic growth, manage key accounts, and collaborate across teams to enh...
2 days ago
$110K - $130K *
Join a team that's redefining DME resupply operations by leading a global, remote call center. Drive revenue growth, optimize performance, and ensure compliance while managing a diverse workforce to e...
Yesterday
Senior Director, Transaction Advisory
$120K - $125K *
Lead the charge in mobilizing significant carbon transactions across Latin America, managing multi-stakeholder relationships and driving strategic initiatives to support forest protection programs und...
4 days ago
Head of Revenue Operations (RevOps)
$150K - $180K *
Lead the charge in optimizing revenue operations, collaborating across teams to enhance GTM strategies, streamline processes, and drive growth. Own the systems and metrics that connect strategy to exe...
4 weeks ago
Manager II, Security Operations
$133K - $204K *
Join a team that's redefining security operations by leading a dynamic Cyber Defense unit. You'll manage SOC performance, drive AI integration, and ensure effective incident response while mentoring e...
3 weeks ago
$110K - $130K *
Elevate your career by collaborating with cross-functional teams to enhance business operations, streamline processes, and drive value through effective analysis and documentation. Your expertise will...
2 weeks ago
Manager, Operations Program Management
$125K - $211K *
Join our dynamic team as you lead new product launches in hardware manufacturing. Oversee cross-functional collaborations, manage operational risks, and drive high-quality production strategies that s...
Reposted 4 weeks ago
Remote Sr. Controller - GovCon
$110K - $130K *
Champion financial excellence by leading a dynamic team, ensuring compliance, and delivering strategic insights to clients. Drive operational efficiency and foster a collaborative environment while ma...
6 days ago
Director, Consumer Digital Experience
$229K - $267K *
Innovate the consumer digital experience by leading a cross-functional team to enhance our website, mobile app, and web portal. Define a multi-year vision, prioritize initiatives, and drive engagement...
3 weeks ago
Manager, Strategy & Operations, Finance Transformation
$110K - $130K *
Transform finance functions into strategic drivers for growth by delivering expert accounting and financial support to clients. Lead engagements, enhance processes, and drive performance improvements...
3 weeks ago
Director, Advanced Cooling Category Management, NA
$190K - $200K *
Drive global mechanical category strategy for advanced thermal management systems, ensuring optimal cost, quality, and reliability across a diverse supplier ecosystem while supporting scalable data ce...
Reposted 2 weeks ago
Senior Financial Analyst (Operations)
$66K - $105K *
Help us optimize financial performance through advanced analysis and modeling. Collaborate with business leaders on budgeting, forecasting, and strategic initiatives, providing insights to drive reven...
Reposted 2 days ago
$110K - $118K *
Join a team that's driving strategic financial decisions by managing complex Treasury activities, analyzing risks, and enhancing operational efficiencies. Influence liquidity and banking relationships...
1 week ago
$164K - $273K *
Join a team that's advancing global scientific engagement through strategic conference planning and execution. Collaborate across functions to elevate medical affairs and enhance the impact of evidenc...
Reposted 3 weeks ago
$110K - $130K *
Lead the charge in overseeing high-impact projects, driving strategic initiatives, and fostering strong customer relationships while ensuring alignment with business objectives and delivering measurab...
Reposted 2 weeks ago
Senior Manager, Care Management - Transitions of Care
$110K - $173K *
Champion a transformative clinical team, leading 60-70 RNs in delivering exceptional post-discharge care. Drive innovative strategies to enhance patient outcomes and foster a culture of collaboration...
2 weeks ago
Senior Manager Tax Technology and Process Transformation
$126K - $150K *
Pioneer the transformation of tax technology and processes, driving strategic initiatives to enhance operational efficiency, compliance, and user experience through automation and data-driven solution...
3 weeks ago
Director of Operations & Communications
$110K - $130K *
Champion operational excellence by leading communication strategies and process improvements. Collaborate with leadership and teams to ensure effective information flow and accountability, driving ini...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.