Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$93K - $140K *

Lead the charge in advancing cell therapy operations as you collaborate with cross-functional teams to manufacture innovative therapies, ensuring compliance and process optimization while training and...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$113K - $160K *

Champion the quantification of business impact from technology and transformation investments. Lead financial modeling and value realization efforts, translating insights into actionable recommendatio...

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  •   5 - 7 years exp.  •   Media

$343K - $483K *

Oversee medical leadership and strategic direction for Adult and Older Adult Services, ensuring compliance and quality in psychiatric care. Collaborate with community partners to enhance service deliv...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Elevate your career by leading grant compliance and fiscal operations during a pivotal transition. Oversee staff, manage finances, and ensure adherence to federal, state, and local requirements while...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$93K - $125K *

Drive quality assurance in a dynamic lab environment, conducting critical analyses and supporting GMP operations for innovative cell therapy products. Collaborate across departments to ensure complian...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Reimagine operational excellence by leading a regional team to optimize performance, enhance customer satisfaction, and ensure compliance. Drive financial success while fostering a safe and efficient...

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  •   5 - 7 years exp.  •   Transportation

$113K - $188K *

Shape the future of managed care by leading contract negotiations, performance monitoring, and strategic initiatives to optimize reimbursement and enhance payer relationships across healthcare service...

United StatesRemote

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  •   5 - 7 years exp.  •   Business Services

$150K *

Lead strategic management of complex commercial accounts, fostering consultative client relationships. Evaluate risks, educate clients on coverage options, and coordinate multidisciplinary teams to ex...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $150K *

Engage with key stakeholders to drive sales growth across the commercial construction sector in Southern California. Build lasting relationships and implement effective strategies to enhance market pr...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $135K *

Engage with media to elevate San Francisco as a premier destination. Drive PR initiatives, cultivate media relationships, and execute campaigns that showcase the city's attractions and events, while c...

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$205K - $240K *

Accelerate your career by driving growth initiatives in a dynamic environment. You'll identify opportunities, execute strategies, and collaborate across teams to enhance revenue and customer engagemen...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Deliver comprehensive occupational therapy services to diverse adult and geriatric patients, ensuring effective evaluations, goal-setting, and therapeutic interventions while collaborating with multid...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$70K - $89K *

Transform customer service excellence by leading a dedicated team, ensuring efficient product delivery, and fostering strong client relationships while driving sales and compliance in a dynamic enviro...

Today

  •   Less than 5 years exp.  •   Staffing

$116K - $136K *

Help us build robust IT infrastructure by automating processes and enhancing systems. You'll support engineering and operations, ensuring seamless access and compliance while reducing support volume t...

Today

  •   Less than 5 years exp.  •   Information Technology

$171K - $269K *

Transform client relationships by driving growth and innovation in a dynamic consulting environment. Leverage your expertise to navigate complex enterprise challenges and deliver impactful solutions t...

Today

  •   Less than 5 years exp.  •   Business Services

$70K - $150K *

Engage with clients as a dynamic Outside Sales Representative, driving growth through effective prospecting, lead qualification, and solution-oriented sales strategies. Build lasting relationships whi...

Today

  •   Less than 5 years exp.  •   Staffing

$70K - $150K *

Partner with us to drive sales growth by providing tailored work apparel solutions. Engage with clients through prospecting, cold-calling, and in-person meetings while achieving weekly sales goals in...

Today

  •   Less than 5 years exp.  •   Staffing

$110K - $145K *

Join a dynamic team as a hands-on leader driving fundraising technology and operations. Shape strategies, manage systems, and enhance data integrity to empower development efforts and ensure organizat...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$166K - $195K *

Join a dynamic team to redefine money movement experiences, enhancing customer satisfaction through innovative product management. Lead initiatives from concept to launch, ensuring seamless, compliant...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $125K *

Accelerate progress at the intersection of technology and media by leading complex video initiatives. Drive strategic execution across teams, ensuring successful launches and operational readiness for...

Today

  •   5 - 7 years exp.  •   Media

$120K - $130K *

Join a team that's driving sales growth by cultivating key partnerships and providing clinical consultations in the Urology sector. You'll develop strategic plans to achieve territory objectives while...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Drive your career with a pivotal role in migrating capital project accounting to Oracle Fusion PPM. Collaborate with cross-functional teams to design solutions that enhance financial processes and ens...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the execution of complex, multi-phase projects, ensuring timely delivery within budget and quality standards. Collaborate with cross-functional teams and maintain accountability for project progr...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$90K - $120K *

Drive financial excellence by collaborating across teams to enhance planning and reporting processes. This role blends detailed analysis with strategic insight, offering visibility into key leadership...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Shape the future of construction safety by reviewing plans for compliance with building codes and regulations. Collaborate with architects and engineers to ensure quality and safety in community proje...

Reposted today

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.