Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Average Salary: $142,597
Staff Scientist, Bioinformatics/RWD
$158K - $197K *
Transform real-world health data into actionable insights by leveraging advanced bioinformatics and AI techniques. Lead innovative analyses in oncology and genomics, facilitating cross-functional coll...
Reposted yesterday
Internal Communications Manager, Viasat Government
$121K - $191K *
Shape the future of internal communications by leading strategic initiatives that engage and inform a diverse workforce of 2,000+ employees in the government sector, ensuring alignment with business g...
Yesterday
$165K - $210K *
Elevate your recruiting career by driving strategic hiring across Finance, Legal, and Business Strategy teams. Collaborate with leadership to shape hiring strategies and enhance candidate experiences...
Yesterday
Senior Software Engineer, Infrastructure
$145K - $175K *
Transform infrastructure by building and maintaining CI/CD pipelines, automation, and tooling to enhance engineering productivity and operational excellence in a fast-paced environment...
Yesterday
Softgoods Development Engineer
$175K - $215K *
Accelerate progress at the intersection of engineering and product development. Drive softgoods from concept to production, collaborating with cross-functional teams to solve challenges and ensure qua...
Yesterday
Operations Director - Remote in Southern Region
$110K - $130K *
Oversee operational and clinical performance across mammography centers, ensuring quality, staffing efficiency, and patient experience. Lead a team of Area Managers while driving portfolio-level metri...
Yesterday
$80K - $130K *
Elevate your career by leading a dynamic accounting team, ensuring accurate financial reporting and compliance. Drive process improvements and oversee lease accounting operations while collaborating w...
Yesterday
$100K - $120K *
Contribute to a high-impact voice infrastructure team, ensuring seamless telephony systems and customer interactions. Diagnose and resolve complex VoIP issues while collaborating with cross-functional...
Reposted yesterday
Operational Test and Evaluation (OT&E) Ground Test and Planning Support
$110K - $130K *
Lead the charge in operational test and evaluation for ICBM systems, developing and executing ground test plans, analyzing data, and providing critical support to ensure mission success and safety in...
Reposted yesterday
Defense Attorney (Workers' Compensation) - 5-8k sign on Bonus
$155K - $203K *
Champion your legal expertise in workers' compensation defense, managing cases and providing strategic counsel. Collaborate with clients and lead litigation efforts while working remotely in your lice...
Yesterday
Senior Product Manager, Machine Learning
$150K - $210K *
Transform manufacturing processes by owning ML and physics simulations. Drive the path to accurate part development through predictive modeling and user-driven design, maximizing efficiency and minimi...
Reposted yesterday
Senior Product Manager, Machine Learning
$150K - $210K *
Unlock potential by leading machine learning and simulation efforts to enhance manufacturing accuracy. Drive product management, user research, and technical direction to optimize path planning and sp...
Reposted yesterday
Robotics Research Engineer - Robot Simulation and Evaluation
$184K - $356K *
Join a team that's innovating simulation tools for robotics, blending research and product development to enhance machine learning applications. Collaborate across disciplines to deliver cutting-edge...
Reposted yesterday
Deputy Sheriff Cadet - Unclassified
$116K *
Unlock potential by training as a Deputy Sheriff Cadet, gaining essential skills in law enforcement through a comprehensive academy program focused on academics, physical conditioning, and hands-on tr...
Yesterday
Federal Account Manager, Disruptor Tech
$200K - $304K *
Champion strategic relationships in defense tech, driving adoption of advanced AI and computing solutions. Collaborate with teams to align customer needs with NVIDIA's platforms, ensuring growth and i...
Yesterday
$120K - $160K *
Transform manufacturing excellence by ensuring quality standards meet and exceed expectations. Collaborate across teams to drive continuous improvement, resolve quality issues, and enhance processes i...
Reposted yesterday
$105K - $130K *
Manage accounts payable and support accounting operations in a multi-entity NetSuite environment. Collaborate on GL analysis, journal entries, and process improvements to enhance scalability as the co...
Reposted yesterday
$105K - $130K *
Manage the accounts payable function and enhance accounting operations across a multi-entity NetSuite environment, ensuring accuracy and efficiency while supporting process improvements as the company...
Reposted yesterday
$120K - $160K *
Support quality assurance initiatives by collaborating with cross-functional teams to enhance product standards and drive continuous improvement within a dynamic manufacturing environment. Engage dire...
Reposted yesterday
$130K - $170K *
Lead strategic housing finance initiatives, ensuring project feasibility and compliance while fostering collaboration across departments and with external partners to drive successful development outc...
Yesterday
Kidney Post-Transplant Coordinator
$218K - $260K *
Drive clinical excellence in transplant case management, overseeing patient care from evaluation through follow-up. Collaborate with interdisciplinary teams and educate patients and families to enhanc...
Reposted yesterday
$63K - $123K *
Help us enhance end-of-life care by coordinating operations and outreach for a vital program. You'll oversee strategic initiatives, support bereavement services, and collaborate with clinical teams to...
Yesterday
Senior Copywriter, Promotional Medical Writing
$80K - $100K *
Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...
Yesterday
$185K - $275K *
Drive operational excellence by partnering with regional leadership to enhance GTM strategies, streamline processes, and foster collaboration across commercial functions, ensuring accountability and r...
Yesterday
Administrative Assistant - Liver-Small Bowel Transplant Services
$66K - $95K *
Lead administrative support for the Liver Transplant Program, managing patient referrals, scheduling, and communications. Thrive in a dynamic environment while ensuring efficient operations and enhanc...
Yesterday
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.