Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$166K - $210K *

Help us enhance patient care by performing comprehensive optometric evaluations, utilizing advanced diagnostic techniques, and collaborating with healthcare teams to ensure optimal ocular health and v...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$436K - $500K+*

Lead the charge in developing a high-performing engineering team focused on delivering innovative artwork solutions. Drive operational excellence and partner across functions to enhance product strate...

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$250K - $350K *

Lead the charge in designing and executing innovative hardware solutions for an autonomous rail vehicle. Drive technical direction, manage a high-performing engineering team, and ensure successful dep...

Today

  •   8 - 10 years exp.  •   Transportation

$480K - $500K+*

Transform measurement science by leading a skilled team to enhance content performance metrics, ensuring rigorous analysis and fostering individual growth while collaborating with cross-functional lea...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$115K - $140K *

Transform the future of drug development by leading the formulation of complex injectable and sterile products, ensuring quality and compliance from research to commercialization while mentoring a dyn...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $210K *

Join a team that's redefining IT leadership by overseeing strategic operations, enhancing service delivery, and ensuring compliance. Drive innovation and efficiency while aligning IT with business goa...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$79K - $120K *

Join us in delivering exceptional MRI services while ensuring patient safety and comfort. Utilize your expertise to perform high-quality imaging and support patients through their experience in a fast...

Today

  •   Less than 5 years exp.  •   Healthcare

$178K - $307K *

Join a team that's redefining surgical vision sales by leading strategic initiatives, driving revenue growth, and fostering cross-functional collaboration to enhance customer engagement and operationa...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$178K - $307K *

Elevate the U.S. Surgical Vision business by leading sales strategy, driving performance, and fostering cross-functional partnerships. Collaborate with teams to achieve revenue goals and enhance custo...

Irvine, CARemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a dynamic team to enhance settlement operations, ensuring data integrity and standardized protocols across mass tort resolution programs. Collaborate with attorneys and paralegals to streamline p...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate customer success by driving strategic partnerships and maximizing product value. Collaborate across teams to ensure seamless implementation and proactive support, while leveraging AI tools to...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$78K - $90K *

Lead engineering initiatives to design, enhance, and optimize products, ensuring alignment with manufacturing capabilities and performance standards while fostering innovation and usability improvemen...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$85K - $95K *

Lead the charge in delivering exceptional dining experiences by managing food service operations, ensuring compliance with standards, and fostering staff development while maintaining a balanced work...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Bring your expertise to analyze talent acquisition technologies and market trends. Produce insightful research, engage with industry leaders, and present findings to help shape strategic decisions in...

Today

  •   Less than 5 years exp.  •   Media

$160K - $190K *

Transform data security and access across the organization by designing and implementing robust access models in Foundry, ensuring compliance and safety while enabling teams to leverage sensitive data...

Today

  •   5 - 7 years exp.  •   Consumer Technology

$140K - $165K *

Empower your career by managing the evolution of our Foundry Ontology. Collaborate across teams to streamline data integration, enhance business insights, and drive new use cases while ensuring data s...

Today

  •   Less than 5 years exp.  •   Consumer Technology

$71K - $93K *

Join our team as a Fleet Vehicle Administrator, managing vehicle compliance and data across multiple states. This role requires strong organizational skills and a proactive approach to support fleet o...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$83K *

Unlock potential in community health by providing essential medical care and support to individuals in need. Collaborate with a dedicated team to enhance mental health outcomes and ensure comprehensiv...

Today

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Accelerate progress at a leading eCommerce firm by driving global business strategy, overseeing P&L, and enhancing marketplace operations. Leverage your expertise in digital marketing and account mana...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$105K - $145K *

Drive the design and governance of enterprise analytics data, ensuring accuracy and reliability for reporting and self-service dashboards. Collaborate with Data Engineering and manage Tableau for opti...

Today

  •   5 - 7 years exp.  •   Consumer Technology

$160K - $190K *

Drive impactful multi-channel field marketing strategies that enhance demand generation, strengthen customer relationships, and optimize pipeline performance. Lead a high-performing team while collabo...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Accelerate growth by leading consultative sales in financial services, driving opportunities from initial contact to close. Collaborate with cross-functional teams to enhance client engagement and del...

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $160K *

Drive strategic initiatives across partnerships, revenue, and operations. Collaborate with cross-functional leaders to tackle complex challenges in a fast-paced environment, ensuring effective executi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$197K - $264K *

Join a dynamic team to design and scale AI-powered applications, enhancing operational efficiency and decision-making. Collaborate with leaders to drive AI adoption and create impactful solutions acro...

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$96K - $187K *

Shape the future of water resource infrastructure by leading diverse projects, applying advanced structural design techniques, and mentoring engineering staff to deliver innovative solutions in fisher...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.