Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Director of Business Development
$150K - $180K *
Inspire growth by driving enterprise partnerships in healthcare. Leverage your sales expertise to lead complex cycles, build relationships with C-suite stakeholders, and shape strategic initiatives in...
Today
$110K - $130K *
Advance your career by managing and growing a key business segment, developing strategic sales plans, and fostering relationships with distributors and national accounts to drive revenue and market pr...
3 weeks ago
Lead Counsel, Public Company Governance & Corporate Programs
$165K - $265K *
Champion governance excellence by leading policy frameworks, enhancing Board operations, and driving AI-enabled improvements. Engage with investors and committees to elevate governance practices at a...
Reposted 4 days ago
Senior Director, Patient Recruitment - Remote
$150K - $180K *
Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...
2 weeks ago
Senior Product Development Manager
$120K - $135K *
Transform the insurance landscape by leading product innovation and development initiatives, enhancing personal Property products to meet member needs and drive profitable growth while ensuring market...
4 weeks ago
Senior Associate, Investments & Fund Partnerships - Third Derivative
$84K - $103K *
Shape the future of startup financing by connecting innovative companies with vital capital solutions. Collaborate with founders and investors to develop tailored fundraising strategies and enhance th...
1 week ago
Global Category Lead - Value & Access, Associate Director
$148K - $201K *
Drive category strategy and supplier relationships to enhance Market Access, Pricing, and Health Economics. Collaborate with cross-functional teams to optimize procurement processes and improve operat...
1 week ago
Director, Client Experience & Relationship Management
$110K - $130K *
Lead the charge in enhancing client experiences by championing a culture of CARE. Collaborate across departments to implement strategic initiatives, develop training programs, and ensure consistent, h...
1 month ago
Sr. Business Analyst, AI & Data
$110K - $130K *
Innovate solutions by bridging business challenges with AI-driven strategies. Lead stakeholder engagement, design value streams, and ensure technology investments yield measurable outcomes through eff...
Today
D&T Sr Project Management Consultant - Talent Community
$110K - $130K *
Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...
Reposted 1 week ago
Director, Field Intelligence Strategy & Governance
$185K - $344K *
Champion the evolution of field intelligence capabilities, driving strategic governance and analytics integration to enhance decision-making and execution support across the organization, ensuring ali...
1 week ago
$80K - $95K *
Optimize the commercial loan documentation process by leading a team, ensuring compliance with regulations, and enhancing workflow efficiency. Engage with various units to deliver high-quality, legall...
1 week ago
Life Sciences Commercial, Management Consulting Principal Director
$150K - $375K *
Join a team that's transforming life sciences through strategic commercial leadership. Drive large-scale engagements, foster client relationships, and deliver innovative solutions that enhance operati...
2 weeks ago
$110K - $130K *
Drive effective resolution of pre-litigation disputes and manage claims while collaborating with legal and business teams to implement best practices and mitigate risks in a dynamic environment...
6 days ago
$135K - $160K *
Transform client relationships by leading customer success strategies, driving utilization, and maximizing retention across enterprise health systems. Oversee a high-performing team to ensure client s...
2 weeks ago
Clinical Development Medical Director, Obesity/Cardiovascular
$274K - $371K *
Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...
Reposted 2 weeks ago
Vice President, Growth (Pharma)
$150K - $200K *
Join a dynamic team to drive growth in the pharmaceutical sector, leveraging your expertise to build relationships, win new business, and deliver impactful solutions that enhance brand performance and...
4 days ago
Sr. Digital Experience Manager
$110K - $130K *
Champion the digital experience by optimizing user flows, managing web content, and enhancing conversion strategies to drive engagement and pipeline growth for a leading B2B SaaS platform...
3 weeks ago
Senior Revenue Operations Analyst
$80K - $100K *
Optimize revenue growth by driving GTM excellence and data-driven insights. Collaborate across Sales, Customer Success, and Finance to establish streamlined operations and enhance performance reportin...
Reposted 3 weeks ago
$95K - $115K *
Advance your career by leading complex projects that drive strategic goals. Collaborate with cross-functional teams to ensure timely delivery, compliance, and risk management while enhancing business...
3 weeks ago
$100K - $120K *
Lead the charge in managing complex projects that drive strategic goals. Oversee project lifecycles, ensuring timely delivery, compliance, and stakeholder engagement while fostering collaboration acro...
3 weeks ago
$71K - $125K *
Transform client relationships by supporting sales and credit functions, managing lending processes under $10M, and ensuring data integrity. Collaborate with teams to create impactful pitch materials...
Yesterday
$80K - $95K *
Drive analytical excellence by auditing freight contracts and invoices, ensuring compliance and accuracy. Collaborate with teams to enhance audit processes and mentor junior analysts, contributing to...
1 week ago
Business Development Representative
$70K - $110K *
Lead efforts in healthcare sales development by researching and qualifying accounts, engaging senior executives, and collaborating with marketing and sales teams to build a robust pipeline and drive m...
Reposted 3 weeks ago
$80K - $95K *
Explore new business opportunities and build lasting client relationships. Drive the full sales cycle, from prospecting to closing, while collaborating with cross-functional teams to deliver tailored...
Today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.