Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $150K *

Drive the transformation of our accounting function by leading the monthly close, enhancing financial systems, and developing a high-performing team. Leverage AI and automation to improve accuracy and...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $130K *

Lead the charge in optimizing paid search strategies, managing a $700K-$1M monthly budget, and driving growth across multiple platforms. Own end-to-end account management, from keyword strategy to off...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$136K - $160K *

Shape the future of estate planning by leading a cross-functional squad to enhance AI-driven solutions. Own the roadmap, ensure quality, and drive visibility for families' plans while collaborating wi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$205K - $256K *

Transform your career by leading Apollo's data strategy, ensuring the highest quality B2B data for GTM success. Drive product vision, collaborate cross-functionally, and enhance customer experiences t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $165K *

Join a team that's redefining healthcare technology by owning the product roadmap, translating company goals into actionable tasks, and ensuring seamless delivery of AI-driven solutions that enhance p...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Accelerate revenue growth by driving strategic partnerships and sales initiatives. Own a quota, cultivate executive relationships, and implement market strategies to position the organization as a lea...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to driving client success and growth by managing a substantial book of business. Leverage your expertise in account management to foster relationships and influence produc...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$157K - $185K *

Unlock potential by driving relationships with Fortune 500 accounts. Leverage strategic prospecting and consultative selling to deliver exceptional security solutions while managing multiple high-valu...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $140K *

Unlock potential by leading cost management for complex industrial projects. Collaborate with multidisciplinary teams to ensure client objectives are met while delivering value-added services and fost...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Contribute to a dynamic legal team by providing expert counsel on construction contracts, compliance, and risk management. Collaborate with leadership to navigate legal challenges and ensure operation...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Empower enterprise clients by managing complex relationships and driving growth. Leverage your expertise to deliver high-impact solutions, ensuring clients achieve measurable outcomes while expanding...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$141K - $184K *

Drive user engagement by designing top-of-funnel experiences that convert leads into owners. Collaborate with cross-functional teams to optimize acquisition flows and enhance user journeys through dat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$170K - $243K *

Transform product innovation by leading AI-driven strategies and experiments, collaborating across teams to enhance software solutions and improve employee experiences in a dynamic, fast-paced environ...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$192K - $239K *

Drive clinical study design and execution in hematology/oncology, collaborating with cross-functional teams to ensure data integrity and regulatory compliance while fostering relationships with invest...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $253K *

Drive HR transformation by designing future-state processes and AI integration. Collaborate with clients to enhance HR functions, ensuring alignment with business strategies while fostering superior e...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$160K - $192K *

Execute territory business plans to drive commercial performance, engage healthcare providers, and support product launches. Collaborate with cross-functional teams to optimize patient access and ensu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Lead your career with a strategic role overseeing Business Systems & Automation. Manage a team of Salesforce Administrators, drive process improvements, and collaborate with stakeholders to enhance te...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$111K - $167K *

Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$96K - $145K *

Transform service delivery for complex accounts by ensuring SLAs and KPIs are met. Lead governance, performance management, and continuous improvement initiatives while building trusted relationships...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $165K *

Drive growth by leading consultative sales for women's health benefits. Build relationships, tailor solutions, and close deals while managing a strong sales pipeline and collaborating with internal te...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $146K *

Drive digital customer success initiatives by designing and optimizing targeted journeys throughout the customer lifecycle, enhancing engagement and adoption while collaborating cross-functionally to...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$230K - $280K *

Champion analytical development by leading strategy and execution for pipeline products. Drive compliance and quality control while building a high-performing team in a dynamic environment focused on...

United StatesRemote

6 days ago

  •   15+ years exp.  •   Information Technology

$133K - $186K *

Optimize developer engagement by managing the user journey from first touch to activation. Collaborate with teams to enhance the Developer Hub and drive measurable growth through effective lifecycle m...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $115K *

Transform creator-driven ideas into high-quality deliverables by managing influencer campaigns, coordinating production workflows, and ensuring compliance across multiple platforms. Collaborate with c...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$84K - $172K *

Join a team that's driving sales growth in engineered products while ensuring customer satisfaction. Leverage your expertise to build relationships, analyze market trends, and implement effective stra...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.