Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Strategic Account Manager - Affordable Housing
$80K - $95K *
Champion client success by managing enterprise public sector accounts, ensuring seamless adoption of solutions, and driving engagement while collaborating with internal teams to enhance product offeri...
Reposted 4 days ago
$240K - $260K *
Elevate your career by leading utility-scale solar PV and BESS projects. Drive growth, foster partnerships, and enhance project delivery through strategic leadership and operational excellence across...
Today
$120K - $230K *
Unlock potential by driving strategic sales initiatives for major clients. Engage in lead origination, account management, and growth strategies in the Retail and CPG sectors, leveraging industry insi...
Reposted 2 weeks ago
$135K - $162K *
Lead enhancements in Salesforce HealthCloud to optimize solutions and integrations, collaborate with teams, and deliver scalable applications that ensure high-quality data and security compliance for...
Reposted 1 week ago
$102K - $193K *
Elevate your career by leading a dynamic sales team, driving growth through strategic partnerships, and executing innovative healthcare solutions while achieving personal and team sales goals in a col...
3 days ago
Senior Account Executive, LE/GE, GTS
$132K - $170K *
Unlock client growth opportunities through strategic relationships, driving value in a fast-paced B2B sales environment. Collaborate with C-Level Executives across diverse sectors to ensure client sat...
Reposted 2 weeks ago
$101K - $140K *
Join a dynamic team to drive client growth and retention by building trust-based relationships with C-Level Executives, ensuring they maximize value from services while identifying new opportunities f...
2 weeks ago
$77K - $130K *
Unlock potential by leading innovative SaaS initiatives that enhance customer experiences and drive business growth. Collaborate with cross-functional teams to shape product strategy, leveraging AI to...
2 weeks ago
Business Development Manager - Remote Northern California
$100K - $120K *
Elevate your career by driving business growth through strategic sales initiatives. As a key player, you'll identify prospects, foster client relationships, and deliver compelling solutions in fleet m...
3 weeks ago
Senior Director, Product Management, Agentic Platform
$192K - $303K *
Empower innovation as you lead the strategy and development of core platform primitives, driving the future of agentic systems and ensuring product teams can rapidly create and deploy advanced agents...
2 weeks ago
Enterprise Account Executive (US, Remote)
$110K - $130K *
Transform your career by driving enterprise solutions forward. Leverage your SaaS sales expertise to build strong client relationships, effectively manage opportunities, and deliver impactful solution...
Reposted 1 week ago
Director, Digital Product Management
$150K - $180K *
Empower the future of AI-driven digital products by leading strategy, portfolio management, and cross-functional collaboration to enhance user experiences and drive measurable business impact across d...
5 days ago
$262K - $412K *
Engage with us to redefine market strategies and elevate Thrive's positioning. Lead product marketing, competitive intelligence, and commercial enablement to ensure our innovative solutions resonate w...
2 weeks ago
Executive Director, Financial Planning & Commercial Growth
$175K - $210K *
Join a team that's shaping the future of innovation in cancer research by leading financial planning and commercialization efforts to support strategic growth and decision-making across an impactful o...
Reposted 1 week ago
Territory Sales Representative, Orthodontics
$70K - $125K *
Accelerate progress at driving sales growth by building relationships and identifying opportunities within the dental industry. Leverage your expertise to exceed targets while providing exceptional se...
Reposted today
Senior Acoustical & Vibration Engineer
$110K - $130K *
Lead the development of vibration isolation and acoustic engineering capabilities, serving as a key technical resource. Collaborate with consultants and engineers to enhance product offerings and ensu...
1 week ago
$75K - $90K *
Help us optimize customer success by leveraging your expertise to build strong partnerships, drive growth, and ensure satisfaction while enabling organizations to achieve their business objectives and...
3 weeks ago
$125K - $150K *
Drive the transformation of our accounting function by leading the monthly close, enhancing financial systems, and developing a high-performing team. Leverage AI and automation to improve accuracy and...
4 days ago
Senior Director, Transaction Advisory
$120K - $125K *
Lead the charge in mobilizing significant carbon transactions across Latin America, managing multi-stakeholder relationships and driving strategic initiatives to support forest protection programs und...
Yesterday
Enterprise Account Executive - NAMER
$135K - $185K *
Unlock potential by driving enterprise sales growth through strategic account management, leveraging industry expertise, and building strong client relationships to exceed revenue targets and enhance...
2 weeks ago
$158K - $213K *
Oversee day-to-day accounting and treasury operations, ensuring accuracy and compliance. Lead month-end close processes, refine internal controls, and develop a high-performing team while integrating...
Reposted 4 days ago
Associate Director, Product (Data)
$165K - $175K *
Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...
3 weeks ago
$110K - $130K *
Explore a pivotal role in transforming tax compliance into operational confidence. Collaborate with senior Sales Engineers to engage enterprise clients, addressing complex challenges and delivering ta...
1 week ago
Account Executive, Mid Market (Northeast)
$152K - $190K *
Unlock growth by driving IoT solutions for mid-sized customers, managing complex sales cycles, and engaging with executives to deliver impactful sensor data solutions. Your efforts will enhance operat...
6 days ago
$100K *
Drive sales success by exceeding quotas and presenting innovative HCM/WFM solutions. Collaborate with a dedicated team to support proposals and demos, ensuring customer satisfaction and retention in a...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.