Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$120K - $160K *
Help us modernize our systems by owning the intake process and guiding agile delivery. Collaborate with cross-functional teams to enhance our quoting, pricing, and subscription management capabilities...
Reposted 3 weeks ago
$83K - $155K *
Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...
4 days ago
$95K - $110K *
Elevate your career by partnering with enterprise-level prospects, leveraging your consultative selling skills to drive revenue growth and navigate complex procurement processes for transformative dig...
3 weeks ago
Account Executive - Data Center
$100K - $150K *
Unlock potential by driving revenue growth through strategic sales initiatives in data center security solutions. Collaborate with cross-functional teams to develop customer relationships and achieve...
4 days ago
Senior Manager Order Administration
$110K - $130K *
Lead a dynamic team in managing customer orders, ensuring accuracy and timely delivery while enhancing interdepartmental collaboration and customer satisfaction across Sales and Service Delivery opera...
2 weeks ago
$80K - $95K *
Drive agency growth by managing relationships, delivering tailored marketing strategies, and ensuring compliance. Monitor performance and enhance agent operations while expanding business and lowering...
Reposted 3 weeks ago
Senior Reward & Mobility Manager
$180K - $200K *
Accelerate progress at a multinational level by driving the reward and global mobility agenda. Lead the design and governance of compensation structures, ensuring alignment with business needs while p...
Reposted 5 days ago
Director of Cyber Security Operations
$208K - $235K *
Engage in strategic leadership of cybersecurity operations, enhancing organization-wide security across cloud-native and hybrid infrastructures. Drive incident response, digital forensics, and risk-re...
3 weeks ago
Account Executive (High-Ticket Sales)
$250K - $350K *
Transform high-ticket sales by conducting inbound evaluation calls with pre-qualified prospects. Engage in deep discovery conversations, present exclusive membership, and enroll elite real estate prof...
3 weeks ago
$153K - $183K *
Drive the evolution of sales compensation strategies, managing an efficient payment engine for our go-to-market organization while leading a team of analysts to ensure accuracy and compliance in compe...
3 weeks ago
$100K - $120K *
Manage P&L for multiple states, driving pricing strategy and regulatory compliance. Collaborate cross-functionally to enhance product performance and profitability while presenting insights to senior...
3 weeks ago
$150K - $180K *
Join a team that's shaping global regulatory strategy for rare disease therapies. In this pivotal role, you'll lead submissions and agency interactions across the US, EU, UK, and Japan, driving execut...
3 weeks ago
$135K - $160K *
Empower the go-to-market organization by architecting and optimizing revenue operations, driving AI innovation, and enhancing team productivity through strategic systems thinking and advanced automati...
1 week ago
$125K - $145K *
Drive product strategy and modernization for merchant onboarding solutions, collaborating with cross-functional teams to enhance risk management capabilities and ensure market-leading standards in a d...
Reposted 2 days ago
$100K - $120K *
Drive strategic initiatives to uncover and expand business opportunities, generating new sales through targeted contracts and executive-level relationships while mentoring sales teams and managing cus...
3 weeks ago
$150K - $180K *
Develop and lead revenue operations to drive strategic growth, optimizing marketing, sales, and customer interactions while building a high-performing team and implementing scalable processes and tech...
Reposted 3 weeks ago
Senior Product Manager, Device Experience
$130K - $219K *
Drive the vision for Samsara device installations, enhancing user experiences and ensuring rapid, accurate setups. Collaborate with cross-functional teams to optimize the install process, making impac...
Reposted 1 week ago
Senior Account Director (Medical Affairs)
$155K - $175K *
Lead the charge in client partnerships while driving strategic growth and team development. Utilize your expertise to deliver impactful insights and solutions in a fast-paced, evolving environment, en...
Reposted 1 week ago
$65K - $98K *
Champion growth in Alzheimer’s imaging sales by identifying leads, enhancing team efficiency, and collaborating with outside sales to drive referrals and expand market access for innovative healthcare...
2 weeks ago
$110K - $130K *
Transform digital growth strategies by overseeing website, SEO, and campaigns. Drive content distribution, partner marketing, and harness AI for analytics, ensuring effective buyer engagement and meas...
Reposted 1 week ago
$80K - $95K *
Grow your career with us as a key Associate Sales Manager, driving sales in advanced ceramic powders for diverse industries. Collaborate with customers to identify needs, deliver solutions, and achiev...
Reposted 1 week ago
Key Account Director, Majors West
$144K - $200K *
Transform public safety sales by leading a regional team, enhancing performance, and driving success through effective coaching and recruitment. Collaborate across departments to build a predictable p...
4 days ago
Sales Manager, Strategic Accounts
$288K - $400K *
Inspire a high-performing sales team as you drive strategic growth, nurture talent, and foster customer relationships. Shape long-term sales strategies while managing daily operations to maximize reve...
Reposted 1 week ago
National Sales Manager, Professional Development
$110K - $140K *
Unlock growth by leading sales initiatives for professional development products, driving revenue through strategic client engagement, and enhancing team performance with effective sales strategies an...
3 weeks ago
Strategic Account Executive - Northeast
$280K - $400K *
Unlock potential by managing high-value enterprise accounts and advising Fortune 500 executives. Drive growth with innovative SaaS solutions while collaborating across teams to ensure client satisfact...
Reposted 3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.