Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Southeast Region Sales Manager
$110K - $130K *
Execute strategic sales initiatives in the Southeast region, driving growth and managing a $75M portfolio. Collaborate with clients and partners to enhance customer relationships and ensure service ex...
1 month ago
$250K - $300K *
Champion innovation by leading the engineering org, guiding tech strategy, and enhancing collaboration that leverages AI to boost efficiency and quality in software development...
3 weeks ago
$200K - $240K *
Drive the growth of a new revenue organization, leading membership and high-ticket sales to create scalable, predictable revenue strategies. Build processes, mentor a sales team, and operate at the ex...
3 weeks ago
Manager, Corporate Development
$115K - $150K *
Champion strategic growth by leading M&A initiatives, conducting financial analysis, and collaborating with cross-functional teams to drive successful transactions and enhance corporate capabilities...
1 week ago
$180K - $220K *
Develop and execute comprehensive tax strategies to optimize cash flow, ensure compliance, and support acquisition-driven growth. Lead a high-performing tax organization while advising executive leade...
3 weeks ago
Global Enterprise Account Manager
$200K - $235K *
Transform global enterprise customer relationships by driving EHS/ESG success through consultative account management, strategic growth initiatives, and collaboration with cross-functional teams to de...
Reposted 1 week ago
Regional Sales Manager, Western Region (Military Program)
$130K - $150K *
Join a dynamic team to drive sales growth in the Western U.S. as you develop key accounts and optimize channel partnerships. Leverage your expertise to forecast orders and enhance customer relationshi...
1 week ago
Director of Sales Development & Training
$140K - $223K *
Transform sales training and enablement by developing innovative strategies and AI tools to enhance agent performance, optimize customer interactions, and drive measurable improvements across direct-t...
1 week ago
$150K - $200K *
Accelerate progress at the forefront of product innovation, leading a team to drive strategy and customer experience for a key transaction management platform while embedding AI to enhance efficiency...
4 days ago
$450K - $480K *
Join a dynamic team as a leader in enterprise sales, driving growth in the BFSI sector. You'll develop strategies, mentor talent, and build relationships with key stakeholders to deliver transformativ...
6 days ago
$124K - $156K *
Shape the future of AI Services by owning product strategy and execution. Collaborate with engineering teams to define agentic capabilities, drive tool strategies, and establish AI quality standards t...
1 week ago
$190K - $200K *
Elevate your career by driving sales strategy and execution for a dynamic SaaS portfolio. Lead a high-performing team to achieve revenue growth, optimize pipeline management, and enhance customer acqu...
3 days ago
Outside Sales Executive (SLED)
$90K - $250K *
Accelerate your career by driving new business in the SLED sector. Own your territory, build strategic relationships, and deliver innovative IT solutions with support from top-tier engineering teams a...
3 days ago
$250K - $300K *
Lead a dynamic sales team to drive growth in Application Lifecycle Management (ALM) software. Strategize and implement sales processes, analyze market trends, and cultivate key client relationships to...
Reposted 2 days ago
Director, Business Development
$120K - $150K *
Drive new business growth by engaging scholarly publishers, managing the sales cycle, and collaborating with teams to tailor solutions that meet client needs. Leverage industry insights and strategic...
3 days ago
Regional Sales Director - St. Louis
$180K - $215K *
Tackle the challenge of launching a groundbreaking product by leading a high-performing sales team, driving regional execution, and fostering key customer relationships in a dynamic, fast-paced enviro...
5 days ago
$110K - $130K *
Unlock potential by driving strategic growth within enterprise accounts. Lead cross-functional teams to manage client relationships, develop account strategies, and identify new opportunities, ensurin...
Reposted 4 weeks ago
$65K - $150K *
Lead store operations by driving sales, talent development, and customer satisfaction. Collaborate with teams to implement strategic plans, optimize processes, and cultivate a high-performance culture...
3 weeks ago
Director, Applications Engineering
$203K - $280K *
Reimagine the future of manufacturing by leading a dynamic Applications Engineering team. Drive technical assessments, build customer relationships, and ensure seamless communication between clients a...
3 weeks ago
Principal, Global CPQ & Deal Process
$130K - $160K *
Unlock the potential of global quoting processes by owning the end-to-end CPQ workflow. Drive innovation and efficiency through Salesforce integrations, leading implementation projects while enhancing...
Reposted 3 weeks ago
$200K - $250K *
Lead and empower the global sales teams to drive growth, build customer relationships, and align cross-functional efforts while developing high-performing talent in an inclusive culture. Make your mar...
3 weeks ago
$135K - $170K *
Optimize your sales career by managing the full sales cycle for a leading engineering software. Leverage your technical expertise to drive revenue growth and deliver impactful solutions to industrial...
1 week ago
$170K - $180K *
Manage the product line of a flagship revenue integrity system, overseeing operations, feature development, and client communication to enhance product success while leading a dedicated team in a fast...
3 weeks ago
Sales Manager Specialty Fluids
$100K - $120K *
Empower your career as a Sales Manager in the Specialty Fluids sector, driving growth through strategic account management and lead generation while collaborating with diverse teams across North Ameri...
Reposted 2 weeks ago
RVP, Enterprise Sales - Northeast
$231K - $363K *
Grow your career with a dynamic sales role focused on building enterprise partnerships. Drive impactful healthcare solutions by engaging with HR leaders and managing the full sales cycle across the No...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.