Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Director Commercial Compliance
$119K - $186K *
Lead the development of a risk-based compliance framework for U.S. pharmaceutical commercialization, advising senior leaders and ensuring adherence to compliance standards while fostering ethical deci...
1 week ago
$69K - $99K *
Unlock growth by driving sales across academic, medical, and corporate markets. Build relationships, manage opportunities, and collaborate with teams to exceed targets and enhance customer satisfactio...
3 days ago
Vice President, Clinical & Quality Improvement
$120K - $150K *
Drive strategic leadership in quality improvement and clinical transformation initiatives across community health centers, enhancing patient outcomes and operational performance while fostering a cult...
5 days ago
AVP, Cash Management Operations
$82K - $137K *
Lead and enhance Cash Management operations by driving process improvements, ensuring compliance, and fostering a culture of excellence. Collaborate with cross-functional teams to optimize performance...
Reposted 2 days ago
Regional Distributor Manager, field based remote in South Texas
$106K - $130K *
Join a dynamic team as you lead distributor strategies and drive sales growth across South Texas, Louisiana, and Mississippi. Collaborate cross-functionally to optimize performance and ensure successf...
4 days ago
$98K - $183K *
Engage senior-level stakeholders and drive complex sales growth by developing data-driven solutions and strategic account plans, ensuring customer objectives are met and revenue is increased across Co...
Reposted 1 week ago
Sr. Director, Technical Sales Specialist - Downstream BioProcessing
$160K - $190K *
Shape the future of global sales strategy by leading commercial efforts, driving revenue growth, and enhancing customer engagement across diverse market segments in a dynamic, collaborative environmen...
6 days ago
Manager, Emerging Defense & Sustainment Sales
$164K - $201K *
Drive strategic engagement with key defense contractors while cultivating impactful relationships at all levels, creating competitive plans, and leading mutual opportunities to enhance market presence...
4 weeks ago
$120K - $150K *
Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...
Reposted 3 days ago
$130K - $160K *
Transform the future of real estate technology by owning product marketing, driving strategy, and launching innovative solutions that empower sales teams and deliver exceptional value to clients...
3 weeks ago
$110K - $130K *
Advance your career by enhancing the efficiency and effectiveness of our Legal and Compliance function. Lead operational improvements, manage budgets, and implement legal technology solutions in a dyn...
1 week ago
Toyota Sales Manager: Floor Leader
$120K - $180K *
Transform the sales landscape by leading a dynamic team on the floor, driving performance, and developing talent. Engage directly with customers and foster a high-energy environment to achieve excepti...
1 week ago
Senior Counsel, Americas Employment
$196K - $364K *
Lead the charge in shaping employment law strategy across the Americas. Collaborate with cross-functional teams to provide legal guidance on compliance, employee relations, and litigation management...
2 weeks ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive the design and deployment of innovative data and AI solutions, leveraging expertise in LLMs, agentic AI, and cloud technologies to enhance business value and ensure compliance with industry stan...
2 weeks ago
$250K - $275K *
Empower the data landscape by leading a team to create reliable, AI-ready data systems. Own the data platform, establish governance, and ensure data quality for impactful decision-making across client...
1 week ago
$90K - $110K *
Accelerate progress at a growing technology solutions provider by developing new business and building trusted client relationships in the Charlotte Metro area. Leverage managed IT services and cloud...
3 weeks ago
Vice President, Head of Construction
$160K - $200K *
Oversee the execution of multiple utility-scale solar and BESS projects, ensuring on-time, on-budget delivery while managing contractor performance and maintaining safety and quality standards across...
2 weeks ago
North America Commercial and Marketing Director
$150K - $180K *
Pioneer commercial growth across North America by leading sales and marketing strategies. Drive P&L accountability, foster cross-functional collaboration, and ensure alignment with global objectives t...
1 week ago
$100K - $110K *
Transform business opportunities within the public transit sector by leading complex sales cycles and fostering relationships with government agencies to drive growth and implement tailored software s...
Reposted 1 week ago
$140K - $170K *
Transform complex Federal consulting engagements by leading diverse teams, establishing strategies, and ensuring practical outcomes that enhance government capabilities and client trust...
2 weeks ago
$220K - $248K *
Lead the charge in developing innovative financial products through our Banking as a Service platform, utilizing first principles thinking to create a user-focused experience while collaborating acros...
Reposted 3 weeks ago
Account Executive, SME & Growth (Eastern Time Zone)
$80K - $95K *
Join a team that's driving growth in the US SME market by leading the full sales cycle. You'll engage with diverse clients, translating complex fintech solutions into clear business value while exceed...
6 days ago
Account Executive, SME & Growth (Eastern Time Zone)
$80K - $95K *
Engage in driving sales growth by leading the full sales cycle for SME clients. Collaborate with internal teams to ensure seamless onboarding and deliver tailored solutions, while exceeding revenue ta...
6 days ago
Account Executive, SME & Growth (Eastern Time Zone)
$90K - $110K *
Engage with SME clients to drive sales cycles, translating fintech solutions into business value. Collaborate across teams to ensure customer success and exceed revenue targets while refining sales pr...
6 days ago
Senior Legal Director, Global Commercial - 176690
$250K - $320K *
Pioneer strategic legal leadership in a global commercial function, overseeing complex negotiations and managing a high-performing team across multiple regions to enhance operational effectiveness and...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.