Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$80K - $100K *

Explore new business opportunities by leading sales initiatives, engaging clients, and structuring deals. Collaborate with teams for optimal solutions and continuously improve selling skills while man...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $100K *

Empower your career by leading sales in the Federal Market, building client relationships, and structuring impactful deals. Drive market research, network with industry leaders, and collaborate across...

Charlotte, NCRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Engineer innovative data products that empower global businesses. Lead cross-functional teams to define product strategy, manage lifecycles, and drive performance metrics, ensuring alignment with mark...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $98K *

Transform client relationships by owning a portfolio of B2B accounts, driving growth through tailored solutions in FX and payments, and leveraging technology for impactful service delivery...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$154K - $204K *

Champion strategic financial planning and analysis, driving enterprise-wide initiatives and insights. Lead a high-performing team, enhance reporting capabilities, and support executive decision-making...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$218K - $360K *

Lead a high-performing regional sales team to drive market share growth and achieve financial objectives in Advanced Diagnostics. Inspire talent development and implement strategic business initiative...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $155K *

Shape the future of enterprise sales by driving growth and cultivating long-term relationships. Manage complex sales cycles and leverage AI tools to optimize efficiency and insights, ensuring customer...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$103K - $150K *

Join a team that's driving innovative marketing strategies to enhance client acquisition and deepen relationships. Lead integrated campaigns and collaborate with regional leaders to deliver measurable...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$72K - $175K *

Transform the future of commercial property insurance by leading product strategy, analyzing market trends, and enhancing coverage solutions. Collaborate with cross-functional teams to drive innovatio...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$187K - $234K *

Drive the future of patient care by leading product strategy across Virtual Pharmacy, Patient App, and Partnerships. Shape high-impact initiatives, mentor teams, and enhance operational excellence thr...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$91K - $121K *

Optimize the commercialization process by owning end-to-end management, collaborating across functions, and leveraging AI tools to enhance efficiency and scalability, ultimately driving data integrity...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$156K - $234K *

Join a dynamic team to lead the development of AI-driven customer success platforms, enhancing post-sale experiences through innovative technology and automation, while collaborating closely with engi...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$177K - $301K *

Develop and lead strategic client growth initiatives, fostering executive relationships and aligning teams to drive long-term value, retention, and measurable outcomes across a portfolio of enterprise...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$135K - $226K *

Join us to lead integrated User Acceptance Testing across the Product Development Lifecycle. Drive testing consistency, tool adoption, and continuous improvement while ensuring solutions meet business...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate sales growth by managing hardware and service functions across a designated territory. Drive project management and customer relationships to meet revenue and profitability goals while ensu...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$170K - $191K *

Partner with us to lead innovative food & beverage strategies, driving profitability and guest satisfaction across our portfolio while fostering high-performing teams and operational excellence...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$90K *

Accelerate growth by driving new business and nurturing customer relationships in a dynamic logistics environment. This role blends independent fieldwork with cross-functional collaboration, directly...

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$128K - $252K *

Lead the charge in building and managing high-performing software engineering teams. Drive innovation, optimize processes, and deliver high-quality applications while fostering a culture of excellence...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $200K *

Drive growth and innovation by leading commercial strategies in the Media, Entertainment, and Gaming sectors. Collaborate with teams to enhance client relationships, identify new opportunities, and en...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$141K - $188K *

Advance our sales efforts by driving enterprise client acquisition through strategic engagement, effective presentations, and collaboration with cross-functional teams to exceed revenue targets in the...

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Lead strategic operations and analytics within Global Medical Affairs, ensuring excellence in project execution and data-driven insights. Collaborate cross-functionally to align initiatives with corpo...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Transform Global Medical Affairs by leading operations and analytics, ensuring strategic alignment and data-driven decisions. Drive excellence across teams, manage budgets, and foster collaboration to...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$164K - $305K *

Champion excellence by leading a high-performing team to optimize GPO delivery, ensuring strategic alignment and value realization across multiple accounts while fostering strong relationships with se...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$180K - $215K *

Unlock potential by leading regional sales efforts for a groundbreaking product. Drive performance through strategic execution, team leadership, and customer engagement in a fast-paced, entrepreneuria...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive the evolution of the Marketing PMO, enhancing planning, governance, and execution across functions. Lead strategic programs, optimize workflows, and establish metrics to ensure predictable outco...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.