Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$110K - $130K *
Drive new business in Facility Management by identifying prospects, analyzing market needs, and converting leads into clients. Collaborate with marketing and sales teams to deliver tailored solutions...
3 weeks ago
$120K - $145K *
Optimize runtime authorization strategies across diverse segments, driving technical wins and enabling Sales Engineers. Leverage deep IAM and PAM expertise to deliver impactful solutions, ensuring com...
2 weeks ago
$180K - $220K *
Champion operational excellence by leading enterprise merchandising and retail strategies. Drive financial performance, workforce capability, and continuous improvement while ensuring client satisfact...
2 weeks ago
Front Line Sales Leader - Life Sciences - Corporate
$120K - $145K *
Elevate the future of Life Sciences by driving growth and innovation. Lead a high-performing sales team to secure enterprise partnerships, leveraging SaaS and AI solutions to transform customer experi...
2 weeks ago
$150K - $180K *
Shape the future of enterprise sales by leading a dynamic team to drive strategic growth and build lasting relationships with key clients, ensuring successful deployment of innovative solutions in the...
3 weeks ago
$80K - $95K *
Engage with mission-driven organizations to drive growth in housing solutions. Own the full sales lifecycle, from prospecting to closing, while expanding your portfolio and collaborating across teams...
1 week ago
$275K - $340K *
Drive growth by leading sales and customer success teams, refining strategies, and optimizing processes. Shape the commercial landscape while mentoring talent and ensuring high-value customer relation...
1 week ago
Surgical Solutions Sales Manager
$134K - $201K *
Drive sales growth by managing specialty sales activities, developing strategic plans, and fostering high-level clinical relationships. Collaborate with teams to enhance customer engagement and ensure...
Today
Surgical Solutions Sales Manager
$134K - $201K *
Lead the development and execution of specialty sales strategies, expanding customer relationships and driving growth. Collaborate with clinical teams to enhance training programs and ensure effective...
Today
$125K - $150K *
Lead a dynamic team to enhance client partnerships, driving retention and growth for Fortune 500 and global clients. Your leadership will shape strategies, oversee renewals, and ensure exceptional ser...
5 days ago
$210K - $250K *
Champion growth by overseeing revenue operations, driving strategy across sales, marketing, and data analytics. Lead strategic partnerships, optimize processes, and ensure accurate forecasting and dec...
Reposted today
$95K - $115K *
Lead the charge in expanding business across the Northeast U.S. and Canada by building strategic partnerships, managing client relationships, and driving sales growth through innovative packaging solu...
2 weeks ago
$130K - $150K *
Accelerate strategic partner growth through visionary sales leadership, driving revenue and pipeline expansion while cultivating dynamic relationships and actionable growth strategies. Own the partner...
Reposted 2 weeks ago
Senior Director, Sales Enablement
$175K - $210K *
Transform the sales enablement landscape by leading strategic initiatives that empower teams, enhance training, and drive growth in a dynamic marketplace. Collaborate cross-functionally to ensure ever...
3 weeks ago
Sr. Strategic Sales Manager- Western Ohio & Indiana
$112K - $143K *
Drive new business opportunities in B2B payments by leveraging your consultative sales expertise. Manage the complete sales cycle, build strong client relationships, and optimize payment solutions for...
2 days ago
Regional Sales Manager - Midwest
$100K - $250K *
Unlock potential by leading sales initiatives in the public safety sector. Drive revenue growth, manage territory strategies, and build strong client relationships while collaborating with a dedicated...
Yesterday
Regional Vice President of Sales (Lower Midwest)
$175K *
Engage with high-net-worth clients, converting prospects to loyal partners. Leverage provided leads and support to educate about wealth management solutions while developing your sales expertise in a...
Reposted 1 week ago
$120K - $150K *
Engage your expertise to drive revenue growth through strategic enterprise sales. Lead customer relationships across diverse sectors, analyze market trends, and implement effective sales strategies wh...
4 weeks ago
Strategic Sales Director - Public Sector
$130K - $140K *
Accelerate progress at driving growth and expanding market presence through strategic sales planning, client relationship management, and business development in the public sector, ensuring long-term...
2 weeks ago
Business Development Director, US Rockies and West Coast
$125K - $150K *
Optimize business growth by identifying new opportunities and building relationships with key stakeholders. Leverage solution-selling expertise to drive enterprise sales and achieve revenue targets wh...
2 weeks ago
$100K - $120K *
Engage with clients to streamline communication, ensuring seamless project execution by coordinating cross-functional teams and aligning commitment with project goals, while proactively managing risks...
Reposted 2 weeks ago
Regional Sales Manager - Northwest
$80K - $100K *
Unlock potential by driving sales growth in a dynamic territory, cultivating relationships with diverse clients, and leveraging technical expertise to deliver effective packaging solutions that surpas...
Reposted 1 week ago
Area Vice President- Strategic Account Management
$166K - $200K *
Lead the charge in strategic account management by building and nurturing C-suite relationships, guiding a matrix team, and executing high-level strategies for national accounts and cancer centers acr...
6 days ago
$80K - $95K *
Accelerate your career by driving revenue growth and managing key accounts in the Western U.S. and Canada. Focus on expanding customer relationships and delivering value through consultative selling w...
2 weeks ago
$125K - $150K *
Lead the charge in transforming public sector consulting by guiding organizations through digital transformation and ERP implementations, while managing high-impact teams and fostering client relation...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.