Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$122K - $405K *

Drive the global partner marketing strategy, leading initiatives across channels, technology, and strategic partners to enhance demand generation and pipeline growth. Collaborate with cross-functional...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Consumer Technology

$85K - $102K *

Advance the safety and security of team members and assets by leading a dynamic security department. Oversee compliance with regulations, manage operations, and foster team development to ensure a sec...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$85K - $102K *

Drive security excellence by overseeing operations, ensuring compliance with regulations, and fostering team development to protect assets and enhance safety for all stakeholders...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$119K - $142K *

Join a team that's redefining digital operations by leading strategic initiatives, enhancing customer experiences, and driving growth in a fast-paced environment. Shape the future of MODAL Digital whi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $181K *

Champion innovative multi-channel B2B marketing strategies to drive pipeline growth across North American accounts. Collaborate with teams to execute campaigns, optimize performance, and leverage AI f...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $210K *

Lead the charge in strategic AI initiatives, coordinating cross-functional teams to drive program success. Utilize your program management expertise to align priorities, manage risks, and enhance AI c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$176K - $243K *

Unlock potential by driving the adoption of advanced electrophysiology solutions through strategic partnerships, enhancing customer engagement, and fostering relationships with key stakeholders to ens...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Champion innovative solutions in a dynamic, remote environment, driving sales strategy and product development for public safety agencies. Collaborate with teams to deliver impactful presentations and...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $125K *

Lead and develop a high-performing Solution Consulting team, driving strategic engagements and delivering impactful product demonstrations to agency and brokerage clients. Collaborate cross-functional...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$70K - $148K *

Partner with us to build strategic relationships with automotive industry leaders. In this role, you'll drive account growth, manage client interactions, and deliver exceptional service to enhance cus...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$280K - $350K *

Unlock potential by leading a high-performing Enterprise sales team to drive revenue growth, mentor talent, and align strategies across departments, ensuring success in complex B2B SaaS solutions for...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$88K - $105K *

Elevate operational excellence by leading a dynamic service center team, driving performance, and ensuring customer satisfaction through strategic management and continuous improvement initiatives...

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Seeking a strategic leader to drive manufacturing engineering excellence across North America, integrating advanced technologies and lean principles to optimize production systems, enhance performance...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Grow your career with an opportunity to drive sales and build client relationships across a diverse territory. Leverage your technical expertise to promote innovative solutions and achieve results, en...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a dynamic team to develop and implement sales enablement strategies that empower customer-facing teams with essential product knowledge and training, driving organizational success and enhancing...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $125K *

Empower growth by driving strategic account management and sales initiatives. Collaborate with diverse teams to deliver innovative manufacturing solutions, ensuring client success and exceeding revenu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $140K *

Unlock potential by owning executive-level client relationships, driving integrated strategies, and leading action-oriented touchpoints that translate insights into measurable outcomes while championi...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Media

$193K - $256K *

Transform client success by leading a large team to enhance service delivery, drive strategic initiatives, and leverage technology for improved client outcomes across diverse segments in a dynamic env...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Engage in transformative leadership within a new construction division, overseeing project lifecycles from planning to execution. Drive operational excellence, foster team development, and ensure comp...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$145K - $169K *

Elevate franchise operations by leading strategic initiatives, driving performance, and fostering collaboration across teams to achieve business objectives and enhance Coca-Cola's market presence...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$145K *

Drive significant growth by managing the entire sales cycle for mid-market nonprofit clients, nurturing relationships to unlock their potential and optimize the use of our innovative solutions, while...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $110K *

Shape the future of learning by leading innovative enablement programs that empower managers and new hires. Collaborate with cross-functional teams to design impactful training solutions that drive or...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$225K - $275K *

Lead the charge in redefining Total Rewards strategy, enhancing compensation, equity, and benefits to attract and retain top talent while anticipating workforce shifts driven by AI and market trends...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $135K *

Shape the future of our Accounting Operations by leading a dynamic team, ensuring accuracy and efficiency in financial processes, and driving improvements through automation and AI integration...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$130K - $160K *

Elevate your career by driving sales in the SLED sector. This role focuses on building relationships with Washington State Agencies, executing strategies, and achieving revenue targets while collabora...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.