Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$150K - $180K *

Unlock potential by driving Brand P&L through strategic leadership and marketing execution across the Home and Garden division, achieving ambitious sales, GM, and EBITDA goals through integrated omnic...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$110K - $140K *

Accelerate progress at driving sales execution and client relationships across commercial accounts. Lead solution-specific cycles, collaborate with experts, and achieve growth objectives while deliver...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $191K *

Lead product strategy and execution by driving cross-functional teams to deliver high-quality solutions. Own the product lifecycle, prioritize impactful features, and leverage customer insights to ali...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$130K - $195K *

Transform enterprise sales by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology strategies to measurable business outcomes. Collaborate with cross-functional teams to dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $120K *

Lead the charge in enhancing safety standards across multiple construction projects. Collaborate with field teams to ensure compliance and improve practices, making safety a priority and fostering a c...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Lead market expansion and provider relationships through consultative sales strategies, driving revenue growth and pipeline management within a dynamic healthcare environment while leveraging AI tools...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $234K *

Advance your career by leading a dynamic sales team, driving performance, and fostering relationships with healthcare professionals to enhance patient outcomes through innovative solutions...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Champion customer relationships and drive sales strategies to enhance loyalty and achieve targets. Collaborate with teams to execute action plans, manage distributor salesforces, and ensure excellence...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$126K - $191K *

Lead the charge in implementing an integrated risk framework across the enterprise, enhancing resilience and oversight while guiding teams in risk management, business continuity, and crisis response...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Drive growth and enhance customer service across your territory by achieving key sales metrics and fostering relationships with healthcare partners. Engage in both in-person and virtual interactions t...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $124K *

Support client relationships by optimizing campaigns to drive revenue growth, ensuring performance meets KPIs. Collaborate with teams to identify upsell opportunities and deliver strategic insights, f...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$143K - $291K *

Join a team that's dedicated to empowering healthcare professionals through innovative medical devices. Lead a high-performing sales organization, drive revenue growth, and enhance patient care with c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $300K *

Join a dynamic team as you drive enterprise sales across mid-market to Fortune 500 accounts. Own the entire sales cycle, engage multi-stakeholder buying committees, and leverage AI tools to redefine b...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Champion revenue growth and market expansion by leveraging consultative sales techniques to drive adoption of innovative educational solutions in K-12 districts, fostering strong relationships and exc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $150K *

Empower growth by identifying and acquiring new customers in the Food & Beverage sector. Drive strategies to recover inactive accounts and establish sustainable revenue streams across North America, c...

6 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $150K *

Champion growth by acquiring new customers and reviving inactive accounts in the Food & Beverage sector. Drive market expansion through strategic relationship building and technical solutions, ensurin...

6 days ago

  •   5 - 7 years exp.  •   Business Services

$175K - $195K *

Unlock potential by leading strategic M&A initiatives across Europe and APAC. Drive deal execution with autonomy, manage due diligence, and collaborate with senior leadership to shape investment strat...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Lead the execution of complex industrial projects, ensuring budget, schedule, and quality are met. Collaborate with cross-functional teams and clients to drive accountability and success from preconst...

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$175K - $263K *

Empower the financial future of the organization by leading strategic financial initiatives, ensuring compliance, and fostering a culture of transparency and collaboration across teams to drive sustai...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead a dynamic team to enhance customer success, drive retention, and maximize revenue growth. Shape strategies and workflows while collaborating cross-functionally to deliver exceptional value and ou...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Join us to lead and optimize our operations, ensuring seamless processes across revenue, contracts, partnerships, and people management. You'll build a team and systems that empower growth, driving ef...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Staffing

$122K - $405K *

Drive the global partner marketing strategy, leading initiatives across channels, technology, and strategic partners to enhance demand generation and pipeline growth. Collaborate with cross-functional...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Consumer Technology

$85K - $102K *

Advance the safety and security of team members and assets by leading a dynamic security department. Oversee compliance with regulations, manage operations, and foster team development to ensure a sec...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$85K - $102K *

Drive security excellence by overseeing operations, ensuring compliance with regulations, and fostering team development to protect assets and enhance safety for all stakeholders...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$119K - $142K *

Join a team that's redefining digital operations by leading strategic initiatives, enhancing customer experiences, and driving growth in a fast-paced environment. Shape the future of MODAL Digital whi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.