Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$125K - $150K *

Accelerate your career by driving growth in healthcare sales. Leverage your expertise to build relationships with key accounts, navigate complex deals, and shape future services that impact the indust...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Drive growth by developing and executing innovative sales strategies for business solutions, fostering collaboration across teams, and enhancing client relationships to achieve revenue and deposit goa...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $180K *

Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$96K - $144K *

Accelerate progress at player acquisition and retention through hands-on management of paid media, promotions, and analytics. Leverage AI and APIs to drive growth while owning the player-growth P&L in...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Execute high-value construction projects, leading renovations and new builds. Oversee multiple projects while collaborating closely with stakeholders to ensure successful delivery and compliance with...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$115K - $140K *

Join a team that's dedicated to transforming patient engagement through innovative marketing strategies. You'll develop and execute multichannel campaigns, crafting compelling content that drives enro...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Transform your career by driving growth and client success in a dynamic market. Collaborate with cross-functional teams to enhance operational excellence, expand revenue, and deliver exceptional clien...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Drive strategic growth by leading business development and sales operations, optimizing RFP processes, and enhancing performance metrics. Collaborate across teams to ensure alignment and improve outco...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $260K *

Unlock potential by driving new business sales in the Fintech sector, leveraging industry expertise to cultivate strategic relationships and deliver tailored solutions that meet client needs across No...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$88K - $105K *

Partner with us to drive manufacturing excellence by managing project planning, budgeting, and execution. Collaborate across teams to ensure timely delivery, optimize resources, and enhance operationa...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $160K *

Join a team that's driving new business growth in the Food & Beverage industry. Collaborate with sales and OEM teams to leverage our product offerings and shape go-to-market strategies, ensuring strat...

Missouri, USRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Lead the charge in optimizing patient revenue cycle operations, enhancing financial performance, and ensuring compliance while developing team capabilities to drive superior outcomes across healthcare...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$104K - $123K *

Elevate your career as a strategic advisor to mid-market clients, driving growth and revenue. Manage your own portfolio, build lasting partnerships, and uncover new business opportunities in this dyna...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive growth by developing strategic partnerships and accelerating indirect sales through high-performing channel partners. Leverage your enterprise software expertise to exceed revenue goals and empo...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$280K - $300K *

Advance your career with a high-impact sales role focused on driving new business and expanding relationships within large enterprise accounts, leveraging cutting-edge AI technology to deliver measura...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $115K *

Join a dynamic team to drive sales of mission-critical technology for public safety. Engage with emergency response agencies, navigate complex procurement cycles, and deliver innovative solutions that...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$180K *

Empower clients through expert claims management, ensuring fair coverage interpretation and efficient resolutions while fostering strong relationships and strategic advocacy throughout the property an...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$188K - $255K *

Join a team that's empowering predictive modeling excellence. Lead and scale a product management pod while owning the core predictive foundation and driving transformative modeling initiatives in a h...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$136K - $253K *

Champion customer success by leading the migration of SMB accounts to CoCounsel, driving engagement and adoption through consultative selling and strategic outreach. Collaborate with teams to ensure s...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Media

$196K - $240K *

Join a team that's driving drug substance technology transfer and operational excellence across CDMO sites. Lead manufacturing oversight, ensure compliance, and foster cross-functional partnerships to...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive customer engagement through strategic account management and technical expertise in optics, enhancing relationships with key stakeholders in communication technology sectors and achieving growth...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$92K - $160K *

Engineer comprehensive underwriting strategies for complex financial cases. Lead initiatives, mentor junior staff, and ensure compliance with guidelines while fostering strong relationships within a d...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $102K *

Join a team that's dedicated to ensuring compliance and risk management across partner offices. You'll oversee adherence to policies, foster relationships, and support training initiatives while manag...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Champion growth by owning the full sales cycle, educating clients, and driving custom part sourcing for hardware companies. Collaborate with a remote team to deliver exceptional service and build last...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.