Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Enterprise Sales Executive (AI Native)
$125K - $150K *
Accelerate your career by driving growth in healthcare sales. Leverage your expertise to build relationships with key accounts, navigate complex deals, and shape future services that impact the indust...
4 weeks ago
Director Business Solutions Sales & Strategy
$125K - $150K *
Drive growth by developing and executing innovative sales strategies for business solutions, fostering collaboration across teams, and enhancing client relationships to achieve revenue and deposit goa...
3 weeks ago
Senior Product Manager, Payments Gateway
$160K - $180K *
Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...
5 days ago
$96K - $144K *
Accelerate progress at player acquisition and retention through hands-on management of paid media, promotions, and analytics. Leverage AI and APIs to drive growth while owning the player-growth P&L in...
4 weeks ago
$110K - $130K *
Execute high-value construction projects, leading renovations and new builds. Oversee multiple projects while collaborating closely with stakeholders to ensure successful delivery and compliance with...
Reposted 1 week ago
$115K - $140K *
Join a team that's dedicated to transforming patient engagement through innovative marketing strategies. You'll develop and execute multichannel campaigns, crafting compelling content that drives enro...
Reposted today
Strategic Growth Director, Security
$125K - $150K *
Transform your career by driving growth and client success in a dynamic market. Collaborate with cross-functional teams to enhance operational excellence, expand revenue, and deliver exceptional clien...
Today
Senior Director, Strategic Growth
$150K - $180K *
Drive strategic growth by leading business development and sales operations, optimizing RFP processes, and enhancing performance metrics. Collaborate across teams to ensure alignment and improve outco...
Yesterday
VP Sales Fintech - San Francisco Bay Area
$200K - $260K *
Unlock potential by driving new business sales in the Fintech sector, leveraging industry expertise to cultivate strategic relationships and deliver tailored solutions that meet client needs across No...
Today
Project Manager- Manufacturing
$88K - $105K *
Partner with us to drive manufacturing excellence by managing project planning, budgeting, and execution. Collaborate across teams to ensure timely delivery, optimize resources, and enhance operationa...
3 weeks ago
Business Development Manager - Food & Beverage ( VFDs)
$100K - $160K *
Join a team that's driving new business growth in the Food & Beverage industry. Collaborate with sales and OEM teams to leverage our product offerings and shape go-to-market strategies, ensuring strat...
Reposted 2 weeks ago
$120K - $145K *
Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...
5 days ago
$85K - $100K *
Lead the charge in optimizing patient revenue cycle operations, enhancing financial performance, and ensuring compliance while developing team capabilities to drive superior outcomes across healthcare...
Reposted 4 weeks ago
Sr. Mid-Market Account Manager
$104K - $123K *
Elevate your career as a strategic advisor to mid-market clients, driving growth and revenue. Manage your own portfolio, build lasting partnerships, and uncover new business opportunities in this dyna...
Reposted 1 week ago
Channel Account Manager, Senior (Manufacturing)
$110K - $130K *
Drive growth by developing strategic partnerships and accelerating indirect sales through high-performing channel partners. Leverage your enterprise software expertise to exceed revenue goals and empo...
4 weeks ago
Enterprise Account Executive, Ohio Valley
$280K - $300K *
Advance your career with a high-impact sales role focused on driving new business and expanding relationships within large enterprise accounts, leveraging cutting-edge AI technology to deliver measura...
3 weeks ago
Account Executive - Logging Recorder
$85K - $115K *
Join a dynamic team to drive sales of mission-critical technology for public safety. Engage with emergency response agencies, navigate complex procurement cycles, and deliver innovative solutions that...
3 weeks ago
Vice President, Senior Claims Case Manager
$180K *
Empower clients through expert claims management, ensuring fair coverage interpretation and efficient resolutions while fostering strong relationships and strategic advocacy throughout the property an...
4 days ago
Product Lead, Predictive Platform
$188K - $255K *
Join a team that's empowering predictive modeling excellence. Lead and scale a product management pod while owning the core predictive foundation and driving transformative modeling initiatives in a h...
Reposted today
Account Manager, CoCounsel Legal
$136K - $253K *
Champion customer success by leading the migration of SMB accounts to CoCounsel, driving engagement and adoption through consultative selling and strategic outreach. Collaborate with teams to ensure s...
3 days ago
Director, Drug Substance Commercial Manufacturing
$196K - $240K *
Join a team that's driving drug substance technology transfer and operational excellence across CDMO sites. Lead manufacturing oversight, ensure compliance, and foster cross-functional partnerships to...
Yesterday
Regional Sales Manager, Americas NEMs and Labs, Midwest region
$110K - $130K *
Drive customer engagement through strategic account management and technical expertise in optics, enhancing relationships with key stakeholders in communication technology sectors and achieving growth...
Reposted 3 weeks ago
Senior Underwriting Consultant
$92K - $160K *
Engineer comprehensive underwriting strategies for complex financial cases. Lead initiatives, mentor junior staff, and ensure compliance with guidelines while fostering strong relationships within a d...
Reposted yesterday
$81K - $102K *
Join a team that's dedicated to ensuring compliance and risk management across partner offices. You'll oversee adherence to policies, foster relationships, and support training initiatives while manag...
Reposted 2 weeks ago
$100K - $120K *
Champion growth by owning the full sales cycle, educating clients, and driving custom part sourcing for hardware companies. Collaborate with a remote team to deliver exceptional service and build last...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.