Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$145K - $169K *

Transform the South Zone's beverage landscape by driving strategic growth, aligning stakeholders, and executing innovative plans that enhance market performance and profitability across a diverse Coca...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$262K - $412K *

Engage with us to redefine market strategies and elevate Thrive's positioning. Lead product marketing, competitive intelligence, and commercial enablement to ensure our innovative solutions resonate w...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $210K *

Join a team that's shaping the future of innovation in cancer research by leading financial planning and commercialization efforts to support strategic growth and decision-making across an impactful o...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Lead the development of vibration isolation and acoustic engineering capabilities, serving as a key technical resource. Collaborate with consultants and engineers to enhance product offerings and ensu...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive the transformation of our accounting function by leading the monthly close, enhancing financial systems, and developing a high-performing team. Leverage AI and automation to improve accuracy and...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $125K *

Lead the charge in mobilizing significant carbon transactions across Latin America, managing multi-stakeholder relationships and driving strategic initiatives to support forest protection programs und...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$105K - $225K *

Champion growth and profitability by leading a regional underwriting team. Drive strategic initiatives, manage agency relationships, and mentor staff to enhance operational effectiveness and ensure al...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's dedicated to driving client retention and growth. Lead a talented group of account managers, cultivate strategic relationships, and implement innovative solutions to achieve revenue...

Today

  •   5 - 7 years exp.  •   Healthcare

$240K *

Champion client success by building relationships and driving growth in the automotive sector. Leverage your expertise in dealership operations and vehicle remarketing to enhance inventory protection...

2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$135K - $185K *

Unlock potential by driving enterprise sales growth through strategic account management, leveraging industry expertise, and building strong client relationships to exceed revenue targets and enhance...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$158K - $213K *

Oversee day-to-day accounting and treasury operations, ensuring accuracy and compliance. Lead month-end close processes, refine internal controls, and develop a high-performing team while integrating...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $187K *

Elevate your career by leading strategic client programs, ensuring alignment across teams to optimize client success and value realization while managing risks and reporting on progress to stakeholder...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$165K - $175K *

Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Explore a pivotal role in transforming tax compliance into operational confidence. Collaborate with senior Sales Engineers to engage enterprise clients, addressing complex challenges and delivering ta...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$152K - $190K *

Unlock growth by driving IoT solutions for mid-sized customers, managing complex sales cycles, and engaging with executives to deliver impactful sensor data solutions. Your efforts will enhance operat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$108K - $130K *

Lead the charge in executing integrated design projects, guiding a multi-disciplinary team to meet client objectives while ensuring quality, budget, and schedule alignment across diverse industries...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$85K - $107K *

Drive product strategy and enhancements by collaborating across teams to optimize performance, efficiency, and customer satisfaction. Leverage data insights to evolve offerings and ensure alignment wi...

Bridgeton, MORemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$300K *

Drive enterprise sales success by leading complex cycles, building strategic relationships, and collaborating with cross-functional teams to enhance Zuddl's offerings and achieve measurable results in...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Accelerate your career by driving growth in healthcare sales. Leverage your expertise to build relationships with key accounts, navigate complex deals, and shape future services that impact the indust...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Drive growth by developing and executing innovative sales strategies for business solutions, fostering collaboration across teams, and enhancing client relationships to achieve revenue and deposit goa...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$160K - $180K *

Lead the charge in transforming our payment gateway strategy, driving performance and innovation. Collaborate with cross-functional teams to enhance user experience and ensure compliance while optimiz...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$96K - $144K *

Accelerate progress at player acquisition and retention through hands-on management of paid media, promotions, and analytics. Leverage AI and APIs to drive growth while owning the player-growth P&L in...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Execute high-value construction projects, leading renovations and new builds. Oversee multiple projects while collaborating closely with stakeholders to ensure successful delivery and compliance with...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$115K - $140K *

Join a team that's dedicated to transforming patient engagement through innovative marketing strategies. You'll develop and execute multichannel campaigns, crafting compelling content that drives enro...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Transform your career by driving growth and client success in a dynamic market. Collaborate with cross-functional teams to enhance operational excellence, expand revenue, and deliver exceptional clien...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.