Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$60K - $120K *

Accelerate customer success by driving upgrades and expanding product use. In this full-cycle sales role, you'll engage with existing clients, identify opportunities, and close deals to enhance their...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$179K - $280K *

Unlock potential by driving strategic revenue cycle performance and enhancing client partnerships. Lead initiatives across Self-Pay and Patient Financial Experience, leveraging data to influence decis...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $105K *

Join a team that's dedicated to driving sales success by developing strong client relationships and identifying new business opportunities in a competitive environment. Leverage your skills to deliver...

4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $150K *

Lead the charge in building long-term customer relationships while optimizing operations. As a Business Manager, you'll drive strategic growth, manage key accounts, and collaborate across teams to enh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K *

Empower our operations by leading a dynamic team to ensure timely delivery of medical equipment and services, enhancing patient care through collaboration and strategic oversight in a fast-paced envir...

Today

  •   5 - 7 years exp.  •   Healthcare

$107K - $180K *

Lead the charge in empowering sales teams through innovative enablement programs, training, and resources. Collaborate across departments to optimize processes and enhance seller effectiveness, drivin...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $200K *

Lead transformative partnerships in the travel industry, driving strategic growth and revenue. Engage with C-suite executives to secure high-impact deals and elevate market positioning through collabo...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$190K - $250K *

Analyze and evaluate therapeutic opportunities to drive innovation and business development. Collaborate with interdisciplinary teams to assess scientific and commercial viability, ensuring alignment...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $195K *

Advance academic excellence by leading institution-wide initiatives, enhancing student pathways, and driving enrollment growth. Collaborate with Deans and faculty to align academic strategies with mar...

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$180K - $210K *

Drive operational excellence across multiple hospitality venues, ensuring financial success and client satisfaction. Collaborate with GMs and corporate functions while leading business growth in a dyn...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$100K - $120K *

Grow your career with a dynamic role focused on developing strategic accounts, identifying new business opportunities, and delivering impactful solutions in a remote setting with travel requirements...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in driving partner-sourced revenue growth and market expansion through strategic alliances in Data, AI, and Cloud. Collaborate with top technology partners to convert relationships int...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Empower channel growth by managing key partnerships, driving sales acceleration, and collaborating with cross-functional teams to exceed performance goals in the Ohio Valley Region...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $185K *

Drive strategic growth by identifying and developing solution-specific opportunities within key accounts, leveraging industry expertise to influence client transformation initiatives and enhance sales...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Grow your career with a dynamic role focused on driving revenue and expanding relationships in the environmental sector. Utilize consultative selling and strategic prospecting to achieve objectives ac...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$140K - $160K *

Deliver exceptional ERP solutions by driving new business across North America. Own the full sales cycle, engage with C-level executives, and shape sales strategies to achieve significant growth in mi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $100K *

Accelerate progress at a dynamic agency by leading complex client campaigns. Manage project scope, timelines, and budgets while collaborating with cross-functional teams to deliver high-quality result...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $180K *

Join us as a strategic operator to drive high-priority growth initiatives, aligning cross-functional teams and transforming ideas into actionable plans while leveraging AI tools for enhanced efficienc...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Drive client success by enhancing revenue cycle performance and fostering strategic relationships with enterprise clients. Leverage expertise to implement solutions, manage risks, and ensure measurabl...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$91K - $155K *

Drive market growth by establishing trench drain solutions as design standards among engineers. Build relationships, promote products, and influence specifications to enhance sales and market presence...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $110K *

Elevate the impact of early childhood development by managing and expanding the HELP product suite. Drive customer relationships, account growth, and new business development while supporting practiti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$175K - $292K *

Lead the charge in driving demand and revenue growth through innovative marketing strategies, integrated campaigns, and collaboration with cross-functional teams to enhance buyer journeys and optimize...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$89K - $120K *

Transform your sales career by driving revenue growth through strategic partnerships. Manage the full sales cycle, collaborate with teams, and leverage your expertise in cloud computing to attract and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Champion strategic growth by managing key accounts, fostering relationships, and driving sales initiatives. Collaborate with leadership to meet customer needs and exceed performance objectives while r...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.