Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$150K - $180K *
Shape strategic sales initiatives targeting Fortune 2000 accounts. Drive complex sales cycles, engage with C-suite leaders, and leverage AI solutions to meet revenue goals while building a robust pipe...
1 week ago
Sales Manager - IBM National Practice
$80K - $120K *
Accelerate growth by leading a high-performing sales team, driving revenue and customer success through effective coaching, strategy execution, and collaboration with stakeholders to achieve business...
Yesterday
$110K - $130K *
Drive growth by building and scaling credit card acquisition channels through innovative affiliate partnerships, targeted paid search, and social programs, while collaborating with cross-functional te...
1 week ago
Director, Partner Management, Americas
$195K - $241K *
Partner with us to drive growth and adoption across a diverse product portfolio, managing strategic partnerships from design to launch. Collaborate cross-functionally to enhance relationships and ensu...
1 week ago
Account Executive, Enterprise Acquisition
$130K - $160K *
Unlock new business opportunities as you drive sales strategies, engage clients, and close deals. This role empowers you to act autonomously while collaborating with cross-functional teams to exceed c...
Today
People Business Partner, Field Operations (Northeast)
$100K - $140K *
Drive organizational success by partnering with field leaders to align workforce strategies, enhance talent development, and manage workplace resolutions, ensuring effective staffing and engagement ac...
3 days ago
Territory Sales Manager (Nebraska/Kansas)
$91K - $141K *
Empower agency growth by managing relationships and driving performance in Nebraska and Kansas. Lead strategic initiatives, deliver training, and ensure accountability to achieve sales goals while fos...
6 days ago
Director of Strategic Partnerships
$100K - $150K *
Transform the future of business development by building strategic partnerships across key professional services. Drive growth through relationship-building and co-closing deals, while shaping a natio...
3 weeks ago
Director, Business Improvement
$150K - $180K *
Drive strategic initiatives and operational excellence across a global portfolio, partnering with leadership to enhance business performance and deliver measurable outcomes in oncology and rare diseas...
1 week ago
$144K - $189K *
Unlock potential by leading product innovation in clinical genomics. Shape tools for case management and data workflows, ensuring efficiency and quality while collaborating with lab directors and engi...
2 weeks ago
$82K - $112K *
Shape compelling product narratives by leveraging market insights and AI tools. Collaborate cross-functionally to drive go-to-market strategies, ensuring impactful messaging and training materials tha...
1 week ago
$120K - $135K *
Elevate vendor sales through strategic partnerships, driving growth and profitability. Foster relationships with vendor teams, enable partner success, and align on revenue goals to enhance market pres...
Reposted 2 weeks ago
$120K - $150K *
Drive sales growth by building strong vendor relationships and enabling partners. You'll align with internal teams to deliver impactful solutions, ensuring swift onboarding and maximizing revenue thro...
Reposted 2 weeks ago
Director, Client Strategy and Growth
$185K - $210K *
Engage with clients to drive retention and growth strategies, fostering deep relationships and collaboration across teams. Leverage market insights to enhance product offerings and ensure client succe...
4 weeks ago
$150K - $180K *
Champion the growth of our commercial engine by leading business development efforts, forging strategic partnerships, and driving revenue as quantum computing transitions to enterprise applications. C...
1 week ago
$95K - $153K *
Optimize strategic partnerships by managing consultant relationships, driving engagement, and aligning insights with business goals to enhance client retention and sales effectiveness while fostering...
2 weeks ago
Business Development Manager (REQ927)
$95K - $115K *
Pioneer business growth by developing strategic relationships and driving sales initiatives. This role requires effective collaboration across teams to achieve revenue targets and enhance customer sat...
3 days ago
Director, Commercial Project Management
$201K - $251K *
Join us to lead cross-functional project management in a dynamic biotech environment. Drive global commercialization initiatives, ensuring alignment and execution across teams while enhancing operatio...
3 weeks ago
Sales Engineer - Mid Market - Southeast
$109K - $128K *
Empower your career as you collaborate with a dynamic team to drive the adoption of cutting-edge IoT solutions. You'll shape the future of essential industries by enhancing supply chains and ensuring...
Reposted 2 days ago
$100K - $120K *
Lead comprehensive purchasing operations, influencing sourcing strategies and supplier partnerships to achieve production goals and drive continuous improvement in a dynamic environment...
Reposted 2 weeks ago
Regional Vice President Optics - Central
$88K - $120K *
Unlock potential by leading sales teams to drive revenue growth and enhance client relationships. Collaborate across departments to implement strategic plans, ensuring customer success and market expa...
1 week ago
Senior Product Builder, Merchant Onboarding
$122K - $180K *
Redefine the Merchant Onboarding experience by designing and prototyping innovative features. Collaborate closely with merchants to automate processes and enhance product velocity, leveraging AI tools...
1 week ago
$125K - $150K *
Champion digital transformation by leading delivery teams in Salesforce projects, ensuring excellence in project management, client relationships, and issue resolution while mentoring consultants and...
3 weeks ago
$95K - $115K *
Elevate the Managed Services team by leading specialists in review response, social media, and listings management. Drive operational excellence, client satisfaction, and revenue growth while ensuring...
Today
Medical Director, Occupational Health & Workers' Compensation Managed Care
$300K *
Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...
Reposted 2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.