Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$80K - $95K *

Unlock potential by driving new business growth in healthcare settings while supporting key accounts. Engage decision-makers, deliver impactful presentations, and navigate complex sales cycles to enha...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Empower a high-performing sales team to drive revenue growth and exceed targets. Collaborate in a dynamic environment, coaching and inspiring talent while executing strategic sales plans for a global...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$88K - $105K *

Lead the management of pharmaceutical programs, ensuring client satisfaction and operational excellence. Oversee daily activities, supervise staff, and drive strategic planning while maintaining stron...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive new-client acquisition by managing the full sales cycle, from prospecting to contract signing. Collaborate with marketing and commercial teams to deliver tailored solutions and build executive r...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$85K - $107K *

Transform product strategy and enhance service delivery by collaborating across teams to optimize performance and customer satisfaction, ensuring competitive offerings and operational excellence in a...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$270K - $340K *

Unlock potential by driving sales for innovative healthcare compliance solutions. Own the full sales cycle with health plans, transforming initial conversations into lasting partnerships while shaping...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Transform regulatory strategies for rare disease and cardio-pulmonary drug-device programs. Collaborate with cross-functional teams to ensure compliance and drive successful submissions globally, supp...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $185K *

Help us drive growth by partnering with sales and business teams to streamline complex transactions. This role offers a unique opportunity to influence revenue operations and engage directly with clie...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$180K - $195K *

Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $110K *

Lead the charge in overseeing 12-15 locations, driving sales and executing strategic initiatives while fostering a culture of teamwork and engagement across your district...

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$80K - $110K *

Join a team that's driving growth by identifying and closing new client opportunities in experiential marketing. Leverage your network and expertise to engage youth and Gen Z through innovative campai...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$150K - $200K *

Grow your career with a dynamic role focused on driving new business in the healthcare provider space. Leverage your sales expertise to exceed quotas, engage decision-makers, and collaborate with inte...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$246K - $273K *

Build and lead a high-impact marketing organization to drive customer growth, product launches, and performance metrics in a dynamic, Bitcoin-focused environment. Collaborate cross-functionally and ta...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $140K *

Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion new business development by identifying and converting revenue opportunities across enterprise customers and technology partners, driving growth and establishing long-term relationships in a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $181K *

Tackle the challenges of pricing management by leading a dynamic team in developing competitive cost proposals, ensuring compliance with regulations, and driving profitability through strategic analys...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$85K - $112K *

Join a team that's driving innovation in communication technologies. Leverage your sales expertise to expand adoption of our APIs in the Mid-Market segment, collaborating across teams to deliver value...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$115K - $160K *

Transform client relationships by driving strategic growth and innovative solutions. Leverage your expertise in AI and technology to identify opportunities, shape proposals, and ensure successful deli...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$145K - $169K *

Partner with us to drive HoReCa & FSOP strategies, managing relationships with bottlers and executing local market plans while navigating market dynamics and ensuring alignment with strategic goals...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$157K - $283K *

Lead the charge in managing transportation infrastructure projects, ensuring quality and efficiency while driving profitability and collaboration across teams to deliver successful outcomes for client...

RemoteRemote

Reposted today

  •   11 - 15 years exp.  •   Real Estate & Construction

$82K - $180K *

Transform underwriting strategies by managing excess casualty business, fostering relationships with wholesale partners, and ensuring profitable outcomes while adhering to company guidelines and marke...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$120K - $140K *

Empower provider accounts post-launch by driving growth through strategic engagement, tailored training, and effective collaboration with internal teams. Cultivate relationships across diverse healthc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $135K *

Lead the charge in developing and managing enterprise proposals and plans, ensuring compliance and quality across submissions. Collaborate with cross-functional teams to enhance win strategies and dri...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$141K - $207K *

Engage in strategic portfolio management, collaborating with loan officers to oversee complex commercial banking relationships, assess credit risk, and identify growth opportunities while ensuring com...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.