Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$110K - $130K *

Champion enterprise growth by driving strategic account expansion and retention. Collaborate with cross-functional teams to influence executive stakeholders and execute complex sales strategies, ensur...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Drive revenue growth by developing strategic channel partnerships and enabling resellers. This role combines relationship management with hands-on sales execution to expand market reach and ensure mut...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Shape the future of tax strategies by leading our diverse team and managing client relationships. Engage with various industries to deliver tailored solutions and ensure client satisfaction while driv...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$117K - $160K *

Champion profitable growth by managing E&S commercial property and casualty underwriting. Leverage strong technical skills and relationships to assess risks, deliver competitive quotes, and optimize p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$175K - $190K *

Drive growth in AI cybersecurity by engaging key decision-makers, managing the sales cycle, and building lasting relationships. Leverage your expertise to articulate value and collaborate with teams t...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Accelerate channel growth by leading a high-performing team of Channel Managers, establishing strategic partnerships, and driving execution across the ecosystem to enhance overall performance and deve...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $200K *

Transform federal programs by leading owner's representative services, ensuring effective project delivery from inception to closeout. Leverage commercial real estate expertise to advocate for owners...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $200K *

Lead a dynamic team of Equipment Sales Specialists to drive sales growth, enhance customer satisfaction, and innovate equipment offerings in the dental sector while collaborating with cross-functional...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Lead the charge in capital formation and strategic partnerships, driving equity rounds and forging alliances with industry leaders to propel growth and prepare for a public exit in the robotics sector...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$180K - $210K *

Champion revenue growth by leading strategic initiatives, market expansion, and team performance. Drive alignment across functions to achieve organizational goals while fostering partnerships and enha...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$105K - $245K *

Lead the charge in developing and empowering a high-performing sales team. Foster a strong team culture while driving improvement and accountability in a rapidly changing environment, leveraging data...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$95K - $115K *

Analyze market trends and build strong client relationships to drive sales in a dynamic environment. Collaborate cross-functionally to deliver tailored solutions while achieving ambitious revenue targ...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$275K - $325K *

Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $185K *

Lead the charge in optimizing hospital accounts receivable operations, driving cash acceleration, reducing denials, and enhancing revenue realization through strategic partnerships and data-driven dec...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$137K - $175K *

Accelerate progress at a leading media firm by driving advertising revenue, cultivating client relationships, and leveraging data insights to deliver impactful marketing solutions across diverse vendo...

6 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$139K - $250K *

Lead the charge in driving strategic product development for a diverse insurance portfolio, collaborating with stakeholders to enhance performance and achieve revenue targets throughout the product li...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Join a team that's driving growth in premium roofing products by building strategic relationships with key industry players, expanding market share, and providing innovative solutions while managing a...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Lead operational excellence in biopharmaceutical manufacturing, overseeing GMP processes, technology transfers, and clinical supply. Drive strategic initiatives, manage CDMO relationships, and build a...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive operational excellence by leading multi-team managers in executing compliant money movement flows. Collaborate cross-functionally to enhance customer experiences while ensuring risk mitigation a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Join a team that's redefining audit and advisory services by driving full-cycle sales of an innovative AI platform. Collaborate with CPA firms to foster relationships and guide them through a transfor...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$104K - $161K *

Champion growth by managing agency relationships and driving revenue in your territory. Develop and implement best practices to enhance sales performance while analyzing market trends to achieve profi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $95K *

Transform client relationships by delivering exceptional service and support, ensuring seamless communication and issue resolution while collaborating with internal teams to enhance client satisfactio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$160K - $180K *

Elevate your career by driving sales in the U.S. healthcare market, engaging diverse stakeholders, and managing complex sales cycles to expand our national brain-network footprint through strategic pa...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$114K - $144K *

Contribute to sales success by analyzing performance trends, optimizing processes, and collaborating cross-functionally. Shape the future of sales operations through strategic insights, innovative tec...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Elevate your career by driving new business initiatives and enhancing operational efficiency. Collaborate with cross-functional teams to resolve issues and optimize processes, ensuring seamless execut...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.