Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$144K - $180K *

Transform public safety through strategic account leadership, driving sales for drone technology in major agencies. Own the full sales cycle, build deep relationships, and leverage AI tools to enhance...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$150K - $175K *

Drive financial operations and internal controls while leading a remote accounting team. Oversee month-end closes, technical accounting, and ERP transformations to enhance operational efficiency and e...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $325K *

Accelerate your career by leading strategic communications and public policy initiatives that shape the future of AI identity and accountability. Drive visibility, influence industry narratives, and b...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$250K - $275K *

Empower your career by leading strategic partnerships that drive growth in personal lending. You'll negotiate high-impact agreements with top financial institutions and brands, shaping innovative solu...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$156K - $241K *

Oversee the management of demo environments, ensuring seamless integration and maintenance across departments. Collaborate with teams to deliver scalable technical architectures and optimize enterpris...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Transform your career by driving sales growth and market share through strategic territory management, customer engagement, and product training. Collaborate with a dynamic team to enhance distributio...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform partner relationships into measurable success by managing a strategic portfolio of technology and advisory partners. Collaborate across teams to drive growth, co-sell, and enhance operationa...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Champion growth by leading national accounts, driving strategy, and enhancing partnerships with specialty distributors and GPOs. Leverage expertise to ensure product availability and exceed corporate...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive customer acquisition and sales growth by leveraging your network and expertise. Collaborate with internal teams and strategic partners to identify opportunities, build relationships, and exceed...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Grow your career by driving sales and building relationships in the SLED and commercial sectors. Leverage your expertise to identify opportunities, close deals, and collaborate with a dynamic team to...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $190K *

Lead global accounting functions, ensuring integrity and efficiency in financial processes. Supervise teams across multiple locations while enhancing reporting accuracy and compliance within a growing...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Drive revenue growth by developing strategic sales plans and building client relationships in the dynamic Connected TV advertising landscape. Leverage industry knowledge to identify opportunities and...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Shape the future of financial strategy by leading teams in financial planning, analysis, and insights. Collaborate with executives to drive decision-making and optimize company performance through dat...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $95K *

Grow your career by driving sales and expanding market presence in the Encaps & Inclusions sector. Collaborate with cross-functional teams to deliver innovative solutions while managing key accounts a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$126K - $154K *

Unlock your potential as a Senior Accountant, driving financial accuracy and compliance. Collaborate across teams to enhance systems, oversee key accounting functions, and support audits in a dynamic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Join a team that's driving strategic technology initiatives across business domains. As a Program Manager, you'll align projects with objectives, manage interdependencies, and ensure successful delive...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$180K - $215K *

Drive regional sales success by leading a high-performing team, executing launch strategies, and fostering customer relationships to achieve business objectives in a dynamic environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by driving new business growth in mid-market sectors. Own the full sales cycle, from prospecting to closing, while building relationships and shaping strategies for success in a dynam...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Transform business growth by leading global strategies, driving market opportunities, and fostering cross-functional collaboration to enhance profitability and market share in the oil & gas and proces...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$140K - $170K *

Shape the future of sales strategy across the Americas, leading a high-performing team to drive revenue growth through direct and indirect channels while collaborating with cross-functional teams to a...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$325K - $400K *

Join a team that's driving revenue growth in Northern California by leading a high-performing sales organization, developing strategic partnerships, and executing innovative go-to-market strategies in...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $140K *

Drive efficiency and scalability in onboarding processes, enhancing customer experience through innovative strategies and data-driven leadership. Lead a high-performing team to optimize resources and...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $200K *

Drive strategic revenue growth by engaging C-suite stakeholders and closing multimillion-dollar partnerships within large pharmaceutical organizations. Leverage your expertise to navigate complex sale...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.