Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$135K - $175K *

Lead the charge in expanding market penetration and building strategic partnerships within key healthcare organizations, utilizing your expertise to foster strong relationships and drive adoption of i...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $210K *

Develop and lead a high-performing Revenue Enablement team, driving strategic initiatives to enhance sales effectiveness and align enablement programs with evolving business needs in a fast-paced envi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Drive strategic account growth and retention in production print sales. Own the full sales cycle, engage with clients, and identify new business opportunities while leveraging advanced print technolog...

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$126K - $188K *

Join a dynamic team to evaluate and manage commercial mortgage investments, collaborating with developers and brokers. Drive underwriting, pricing, and closing processes while supporting asset managem...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Join a dynamic team to drive sales solutions and foster strong customer relationships within the restaurant sector, enhancing product offerings and customer satisfaction through strategic engagement a...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $95K *

Join a dynamic team to deliver exceptional client service, manage accounts, and enhance relationships with AmLaw firms. Drive success through proactive communication, issue resolution, and a client-fi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$300K *

Drive enterprise sales by managing consultative cycles, advising clients on tailored solutions, and collaborating with teams to ensure seamless transitions. Leverage expertise to navigate strategic de...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Engage with enterprise clients to drive revenue growth through strategic account management, focusing on logistics and supply chain solutions. Build and maintain relationships with key stakeholders wh...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$96K - $118K *

Advance strategic partnerships by managing high-value commercial opportunities from inception to implementation, ensuring seamless coordination among stakeholders and clarity in contractual obligation...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $215K *

Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's dedicated to delivering exceptional client service and operational excellence. As a Program Manager, you'll oversee program execution, account management, and financial oversight wh...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock your potential as a strategic advisor, driving enterprise success on Amazon. Manage complex initiatives, build executive partnerships, and deliver transformative results through innovative adve...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $90K *

Engage with SMB accounts to build pipeline and close value-driven deals. Own your territory, manage sales cycles, and leverage data to drive results. Collaborate across teams to connect solutions with...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$125K - $175K *

Lead the charge in driving industry-specific solutions through innovative showcases. Collaborate with cross-functional teams to enhance customer engagement and partner management, ensuring alignment w...

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Shape the future of pricing strategy by leading deal governance and commercial frameworks. Collaborate across teams to enhance pricing effectiveness and support ARR growth while guiding complex deal s...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $105K *

Collaborate with clients and teams to manage projects, expectations, and delivery, ensuring high standards and strategic growth in a fast-paced medical affairs environment. Leverage experience to iden...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform product strategies by leading the launch and lifecycle management of innovative solutions. Collaborate cross-functionally to identify market opportunities and enhance user efficiency through...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Optimize revenue and profitability as you lead commercial finance, drive pricing strategies, and negotiate pivotal agreements with stakeholders, playing a vital role in shaping financial success acros...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $105K *

Drive revenue growth by managing territory plans and collaborating cross-functionally. Engage with key customers and analyze market trends to identify opportunities. Influence sales strategies while m...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$143K - $208K *

Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Transform supply chain financial management by leading cost analysis, budgeting, and strategic initiatives. Empower a cross-functional team to drive operational excellence and continuous improvement a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$84K - $96K *

Champion customer success by managing and expanding a territory of existing accounts. Drive renewals and upsells through strategic outreach, relationship building, and leveraging partnerships to enhan...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $268K *

Empower a high-performing sales team to drive client acquisition and growth in the Middle Market segment, ensuring strong financial performance and fostering trusted advisor relationships with clients...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Drive new logo acquisition and revenue growth in the healthcare sector by leading complex sales processes, building executive relationships, and collaborating with cross-functional teams to deliver ta...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.