Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$155K - $185K *

Elevate your career by driving growth within enterprise accounts. Utilize a consultative approach to uncover opportunities, engage stakeholders, and close deals, all while collaborating with a dynamic...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $185K *

Unlock your potential by leading a dynamic team to drive channel partnerships, transforming opportunities into revenue-generating relationships across diverse verticals in a fast-growing ecosystem...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $160K *

Drive new business development and revenue growth by leveraging professional networks and sales expertise to secure major client engagements and enhance executive relationships within Fortune 500 comp...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $220K *

Lead the development and execution of a global channel partner strategy, focusing on recruitment, enablement, and growth of VARs, MSSPs, and GSIs. Build a high-performing team to drive international e...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$370K - $490K *

Join a dynamic team to lead enterprise retail sales, driving strategic growth across diverse categories. Coach senior Account Executives, manage complex deals, and build relationships with top merchan...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $240K *

Drive strategic growth initiatives for Navy & Marine Corps, leading business development efforts and fostering partnerships to enhance tactical networking solutions across diverse operational domains...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$111K - $167K *

Optimize the customer journey by leveraging analytics and strategic insights to enhance pipeline generation, forecasting, and sales enablement for a growing Property Care business. Collaborate cross-f...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by driving innovative sales strategies in the regenerative medicine sector. This role involves full-funnel prospecting, building relationships with key stakeholders, and designing imp...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$107K - $125K *

Join a team that's transforming industrial automation by driving sales of advanced robotic solutions. Leverage your expertise to build strategic partnerships, enhance customer relationships, and expan...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Drive new business growth by owning the full sales lifecycle, engaging senior leaders, and closing complex SaaS deals in the ERP space. Build relationships, uncover opportunities, and translate comple...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $95K *

Transform client relationships by leading strategic projects, ensuring quality and alignment across teams. Collaborate with stakeholders to drive success and meet client expectations while fostering g...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive plant-level sales strategies and cultivate customer relationships to enhance beverage production. Collaborate with teams to identify opportunities and deliver solutions, ensuring consistent prod...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Bring your expertise to drive revenue growth in healthcare through consultative sales and strategic partnerships. Own the full sales cycle, collaborate cross-functionally, and mentor future hires in a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $105K *

Analyze purchasing processes and vendor relationships to enhance operational efficiency. This role offers hands-on execution with potential for leadership, focusing on project ownership and strategic...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Join a team that's dedicated to driving sales success through strategic planning, team development, and strong leadership. Collaborate with sales reps to achieve goals and foster a positive work envir...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$83K - $166K *

Take ownership of CRM strategy in your territory, leading sales teams to achieve sales goals, enhance market presence, and drive profitability while ensuring compliance and quality improvement in card...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$111K - $167K *

Elevate customer success by owning strategic relationships and technical solutions. Drive adoption and outcomes for a portfolio of accounts, collaborating across teams to ensure seamless implementatio...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Unlock potential by leading product analysis and lifecycle strategy for a diverse portfolio, driving profitability through market insights and cross-functional collaboration to enhance product perform...

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Empower your career by driving strategic sales initiatives within large healthcare organizations. Own the full sales cycle, build executive relationships, and position a leading clinical collaboration...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$285K - $385K *

Lead regulatory due diligence for clinical/commercial assets, assessing risks and strategies for licensing, acquisitions, and partnerships. Collaborate across teams to ensure regulatory integration in...

RemoteRemote

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$200K - $240K *

Drive enterprise-wide financial planning and analysis, collaborating closely with executive leadership to build and stress-test models that inform strategic decisions for a growth-stage SaaS business...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $120K *

Drive revenue growth by leading high-performing sales teams and executing strategic sales initiatives. This role combines leadership with deep expertise in performance marketing to achieve ambitious b...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$158K - $199K *

Join a dynamic team to lead, coach, and develop sales associates, driving revenue growth through strategic execution and talent retention. Foster C-level relationships and enhance team success in a co...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$70K - $100K *

Transform your career by leading a dynamic sales team, driving growth, and fostering customer relationships. You'll develop talent, achieve sales goals, and contribute to a thriving business environme...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Empower your career by managing a team of Mortgage Loan Originators, driving loan production, and fostering key referral relationships while ensuring compliance and enhancing customer experiences in a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.