Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
AVP, Senior Product Manager - Agentic Workflows
$120K - $145K *
Explore innovative AI workflow solutions aimed at enhancing business processes. Collaborate with various teams to identify challenges, prototype solutions, and guide projects from conception to produc...
Reposted 2 weeks ago
Sales Manager, Commercial Claims
$89K - $166K *
Help us drive growth as you lead a team focusing on Commercial Claims, enhancing key relationships and achieving sales objectives while managing strategic accounts and fostering talent development wit...
Reposted today
Strategic Client Partner, Clinical
$250K - $350K *
Drive strategic account management in a hybrid role, fostering relationships with clinical stakeholders to enhance client engagement and expand revenue through trusted partnerships and targeted soluti...
Reposted 2 weeks ago
Senior Director, Actuarial Services
$235K - $270K *
Unlock potential by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercial growth while translating complex...
Today
$235K - $354K *
Shape the future of sales leadership by driving regional strategies, managing a high-performing team, and fostering customer relationships to achieve revenue growth and operational excellence in the l...
1 week ago
$150K - $180K *
Pioneer the development of innovative technology solutions, driving product strategy and AI integration to enhance operational efficiency and customer experience across the insurance lifecycle. Lead a...
Today
General Manager, Venture & Private Equity
$275K - $325K *
Drive the venture and private equity business by owning strategy, partnerships, and P&L. Collaborate with teams to establish Flex as the primary financial institution in the sector, leveraging your ex...
2 weeks ago
Territory Sales Representative
$81K - $121K *
Transform retail partnerships by coaching top sellers, driving sales growth, and executing strategic plans to enhance agricultural product adoption and profitability in a dynamic, remote environment...
1 week ago
$130K - $228K *
Drive growth by leading strategic initiatives within the US Air Force, championing innovative data solutions to modernize operations and enhance mission success across defense programs while collabora...
2 weeks ago
$150K - $183K *
Join a team that's driving growth by acquiring and managing Mid-Market accounts. You'll identify prospects, manage the sales cycle, and build lasting relationships to exceed revenue targets in a dynam...
Reposted today
Executive Director Senior Lead Product Manager Client Management Salesforce CRM
$139K - $239K *
Empower client management by leading product vision and execution across key capabilities. Collaborate with cross-functional teams to enhance advisor and client experiences while ensuring compliance a...
Reposted 3 days ago
Executive Director Senior Lead Product Manager Client Management Salesforce CRM
$139K - $239K *
Accelerate progress at the forefront of product management, leading initiatives that enhance client management capabilities. Collaborate with cross-functional teams to define vision, prioritize roadma...
Reposted 1 week ago
Vice President, Marketing - Stadiums
$150K - $160K *
Elevate marketing strategies across stadium venues, driving revenue growth through mentorship, performance metrics, and innovative technology integration while ensuring alignment with organizational s...
3 weeks ago
Manager, Commercial Transformation
$110K - $130K *
Empower sales excellence by driving strategies, training teams, and analyzing market trends to enhance revenue growth and customer relationships. Collaborate across departments to optimize performance...
3 days ago
Senior Manager, Corporate Strategy
$125K - $150K *
Empower strategic decision-making by driving data analysis and recommendations. Collaborate with senior leadership to shape initiatives, build financial models, and leverage AI tools, ensuring impactf...
2 weeks ago
Territory Manager, Communications & Software - North Central US
$108K - $130K *
Accelerate progress at the forefront of electrical grid technology by driving sales and customer engagement across multiple product lines. Leverage your expertise to develop strategies that meet custo...
Reposted 1 week ago
Business Solutions Manager, MSP & Systems of Record
$100K - $120K *
Lead the strategic direction and management of technology solutions in mortgage operations, ensuring seamless integration and operational excellence across key systems while collaborating with stakeho...
Yesterday
$95K - $115K *
Lead the charge in managing complex construction projects, overseeing field operations, ensuring safety and quality, and mentoring junior staff while driving project performance from mobilization to c...
5 days ago
$149K - $248K *
Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...
3 weeks ago
Senior Sales Executive, Supply Chain Finance
$125K - $150K *
Take ownership of driving new-logo growth for our Supply Chain Finance solution. Engage with senior executives, manage the full sales cycle, and develop strategies to acquire high-value customers in f...
3 weeks ago
SaaS Renewal Account Representative
$75K - $126K *
Join a team that's dedicated to enhancing client relationships and driving success through strategic SaaS solutions. You'll ensure satisfaction, maximize revenue, and foster growth within key accounts...
Today
$150K - $190K *
Drive member activation by leading a cross-functional team to optimize outreach, incentives, and messaging strategies. Own the activation roadmap and funnel metrics to enhance engagement and ensure sc...
3 weeks ago
Account Manager, Molecular Diagnostics, QIAstat (Midwest)
$100K - $120K *
Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...
1 week ago
Principal, Strategic Partnerships
$190K - $296K *
Advance strategic partnerships by engaging with top tech companies, driving growth through innovative collaborations. Lead negotiations from inception to launch, ensuring impactful results for family...
Reposted 1 week ago
$75K - $100K *
Transform customer experiences by leading daily operations, ensuring compliance, and empowering team performance in a dynamic collision center environment. Drive success through effective management a...
Reposted today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.