Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$120K - $145K *

Explore innovative AI workflow solutions aimed at enhancing business processes. Collaborate with various teams to identify challenges, prototype solutions, and guide projects from conception to produc...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$89K - $166K *

Help us drive growth as you lead a team focusing on Commercial Claims, enhancing key relationships and achieving sales objectives while managing strategic accounts and fostering talent development wit...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$250K - $350K *

Drive strategic account management in a hybrid role, fostering relationships with clinical stakeholders to enhance client engagement and expand revenue through trusted partnerships and targeted soluti...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$235K - $270K *

Unlock potential by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercial growth while translating complex...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$235K - $354K *

Shape the future of sales leadership by driving regional strategies, managing a high-performing team, and fostering customer relationships to achieve revenue growth and operational excellence in the l...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Pioneer the development of innovative technology solutions, driving product strategy and AI integration to enhance operational efficiency and customer experience across the insurance lifecycle. Lead a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$275K - $325K *

Drive the venture and private equity business by owning strategy, partnerships, and P&L. Collaborate with teams to establish Flex as the primary financial institution in the sector, leveraging your ex...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $121K *

Transform retail partnerships by coaching top sellers, driving sales growth, and executing strategic plans to enhance agricultural product adoption and profitability in a dynamic, remote environment...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$130K - $228K *

Drive growth by leading strategic initiatives within the US Air Force, championing innovative data solutions to modernize operations and enhance mission success across defense programs while collabora...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $183K *

Join a team that's driving growth by acquiring and managing Mid-Market accounts. You'll identify prospects, manage the sales cycle, and build lasting relationships to exceed revenue targets in a dynam...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Business Services

$139K - $239K *

Empower client management by leading product vision and execution across key capabilities. Collaborate with cross-functional teams to enhance advisor and client experiences while ensuring compliance a...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$139K - $239K *

Accelerate progress at the forefront of product management, leading initiatives that enhance client management capabilities. Collaborate with cross-functional teams to define vision, prioritize roadma...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Elevate marketing strategies across stadium venues, driving revenue growth through mentorship, performance metrics, and innovative technology integration while ensuring alignment with organizational s...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Empower sales excellence by driving strategies, training teams, and analyzing market trends to enhance revenue growth and customer relationships. Collaborate across departments to optimize performance...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Empower strategic decision-making by driving data analysis and recommendations. Collaborate with senior leadership to shape initiatives, build financial models, and leverage AI tools, ensuring impactf...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$108K - $130K *

Accelerate progress at the forefront of electrical grid technology by driving sales and customer engagement across multiple product lines. Leverage your expertise to develop strategies that meet custo...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead the strategic direction and management of technology solutions in mortgage operations, ensuring seamless integration and operational excellence across key systems while collaborating with stakeho...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Lead the charge in managing complex construction projects, overseeing field operations, ensuring safety and quality, and mentoring junior staff while driving project performance from mobilization to c...

5 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$149K - $248K *

Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Take ownership of driving new-logo growth for our Supply Chain Finance solution. Engage with senior executives, manage the full sales cycle, and develop strategies to acquire high-value customers in f...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$75K - $126K *

Join a team that's dedicated to enhancing client relationships and driving success through strategic SaaS solutions. You'll ensure satisfaction, maximize revenue, and foster growth within key accounts...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $190K *

Drive member activation by leading a cross-functional team to optimize outreach, incentives, and messaging strategies. Own the activation roadmap and funnel metrics to enhance engagement and ensure sc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Advance healthcare solutions by driving sales of innovative diagnostic instruments. Engage with key stakeholders to promote QIAstat-Dx systems, ensuring successful adoption and customer satisfaction t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $296K *

Advance strategic partnerships by engaging with top tech companies, driving growth through innovative collaborations. Lead negotiations from inception to launch, ensuring impactful results for family...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$75K - $100K *

Transform customer experiences by leading daily operations, ensuring compliance, and empowering team performance in a dynamic collision center environment. Drive success through effective management a...

Reposted today

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.