Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$150K - $180K *
Lead the charge in building and scaling strategic partnerships to drive revenue growth. Oversee the entire partner lifecycle, from selection to enablement, ensuring successful collaboration and measur...
3 weeks ago
$180K - $220K *
Transform the product marketing landscape by leading go-to-market strategies for cutting-edge AI and cloud solutions. Collaborate cross-functionally to craft compelling narratives that resonate with c...
Reposted 4 days ago
Director, Commercial Support & Administration
$143K - $197K *
Accelerate progress at a global scale by leading business development initiatives, managing teams, and crafting strategic plans to drive revenue growth while navigating complex client relationships an...
3 days ago
Channel Manager, North America
$100K - $120K *
Lead the charge in developing and executing channel strategies to drive growth, onboard high-performing partners, and enhance relationships with distributors in the life sciences sector...
2 weeks ago
$190K - $237K *
Accelerate your career by leading partner sales initiatives across AMER. Drive growth through strategic channel partnerships, mentor your team, and enhance collaboration with direct sales to achieve m...
2 weeks ago
Director of Development - Midas Hospitality
$110K - $130K *
Lead transformative real estate development projects across hospitality, residential, and retail sectors. Oversee all phases from acquisition to completion, ensuring alignment with financial and opera...
1 week ago
Senior Director, Facilities, Real Estate & Security Operations
$159K - $215K *
Join a team that's driving operational excellence across 25+ sites, overseeing facilities, real estate, and security operations to ensure safe, efficient environments that support high-quality care de...
4 days ago
$90K - $110K *
Empower global customer success by managing and growing key accounts while driving new business opportunities. Utilize consultative sales techniques to connect technical solutions to business needs, e...
Reposted 2 weeks ago
Regional Sales Director - Richmond
$180K - $215K *
Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...
1 week ago
Director, Corporate Sales - Consulting
$170K - $230K *
Accelerate growth by leading a high-performing sales team in the Professional Services & Consulting sector. Drive strategy, performance, and revenue while fostering a culture of collaboration and exce...
2 weeks ago
$80K - $95K *
Drive regional sales growth by establishing objectives, building customer relationships, and enhancing product offerings. Leverage industry expertise to meet quotas and improve sales systems while fos...
3 weeks ago
$130K - $150K *
Unlock potential by leading the full sales cycle in healthcare, engaging C-suite executives and driving strategic decisions. Leverage your experience to meet quotas, build account strategies, and enha...
Reposted 4 days ago
Enterprise Sales 1 - Providers (East)
$93K - $113K *
Empower healthcare providers by driving enterprise sales strategies, managing client relationships, and leveraging cross-functional teams to enhance patient experience and operational effectiveness in...
3 weeks ago
Product Manager - Customer Data Exchange
$86K - $138K *
Lead the strategy and execution of enterprise data exchange products, ensuring secure and standardized data sharing. Collaborate with stakeholders to drive interoperability and maximize business value...
4 weeks ago
Senior/National Account Director, Market Access
$158K - $250K *
Join a team that's redefining market access strategies in the pharma industry. Leverage your expertise in managed care and payer relationships to drive coverage and reimbursement for innovative therap...
5 days ago
Regional Sales Director - Birmingham
$180K - $215K *
Drive regional sales success by leading launch execution, building high-performing teams, and fostering customer relationships. Collaborate cross-functionally to achieve strategic goals in a fast-pace...
1 week ago
Senior Director, Market & Competitive Intelligence
$170K - $200K *
Drive market and competitive intelligence initiatives to enhance strategic decision-making across teams. Build a high-performing function that delivers insights on customer behavior, market trends, an...
1 week ago
Western US Regional Sales Manager
$108K - $130K *
Lead and grow sales across the Western U.S. for architectural products. Drive revenue, build high-performing teams, and provide technical support to ensure successful project execution and customer sa...
4 days ago
VP, Regulatory Counsel (Transactions, Projects, & Business Initiatives)
$180K - $268K *
Transform your career by leading regulatory strategies for complex transactions in reinsurance and M&A. Collaborate with global teams to navigate regulatory landscapes and ensure compliance while driv...
4 days ago
Senior Director, Commercial Supply Chain
$180K - $200K *
Champion commercial manufacturing excellence by leading technical operations, ensuring on-time delivery of drug products and APIs, and collaborating with regulatory teams to meet compliance and perfor...
Reposted today
$180K - $220K *
Engage with cross-functional leaders to elevate product strategy and execution. Drive innovation in product development, leveraging AI to enhance customer value and business performance across a diver...
1 week ago
Regional Sales Director - New Orleans
$180K - $215K *
Lead regional launch initiatives, driving sales performance and team success through strategic execution and strong customer engagement in a fast-paced environment...
1 week ago
$130K - $160K *
Accelerate your career by driving business development in the biotech sector. Build relationships, consult on data solutions, and enhance sales opportunities while collaborating with cross-functional...
2 weeks ago
$189K - $222K *
Champion client success by leading post-sale operations, ensuring seamless onboarding, delivery, and retention. Drive growth through strategic account management and operational excellence while foste...
2 weeks ago
$110K - $135K *
Take ownership of our paid media strategy across multiple platforms, driving profitable growth and optimizing campaigns. Lead a team to analyze performance, forecast budgets, and innovate with emergin...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.