Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$131K - $225K *

Help us drive partner sales and strategy by building relationships, leveraging AI tools, and fostering a culture of inclusivity within the retail landscape, empowering growth and ensuring customer suc...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$275K - $300K *

Join a dynamic team as you lead quality and technical governance for mission-critical facilities, ensuring operational readiness and continuous improvement across the facility lifecycle from design to...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Information Technology

$91K - $109K *

Lead the charge in maintaining financial integrity by overseeing accounting operations, ensuring compliance with nonprofit standards, and managing audits. Collaborate with finance leadership to produc...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead large-scale automation projects, guiding teams through all phases with a focus on customer satisfaction, operational excellence, and financial management in a collaborative environment...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$185K - $215K *

Drive the development of Contract Financials, collaborating with cross-functional teams to enhance value-based care products. Own the roadmap, prioritize client needs, and ensure successful feature de...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $130K *

Drive financial excellence by leading cost accounting operations, ensuring accurate reporting and analysis. Collaborate across departments to support strategic business decisions and contribute to tim...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$140K - $170K *

Champion the go-to-market strategy for streaming advertising, leading a product marketing team to craft compelling messaging and drive revenue growth. Collaborate across departments to ensure alignmen...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$404K - $500K+*

Transform the Federal Civilian landscape by leading sales teams to drive adoption of cybersecurity and data solutions. Cultivate executive relationships, establish GTM strategies, and achieve multi-mi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$109K - $186K *

Champion business growth across European defense markets by developing strategies, engaging stakeholders, and managing sales cycles. Build long-term relationships to position solutions as the preferre...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$122K - $187K *

Grow your career by driving strategic sales initiatives within key accounts. Collaborate with C-suite executives to deliver tailored technology solutions, ensuring exceptional customer experiences whi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Empower strategic growth by developing and executing multi-year partner strategies. Collaborate with sales and executive teams to enhance alliances, drive revenue, and foster innovation across North A...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$62K - $112K *

Transform member engagement by proactively addressing concerns, coordinating solutions, and enhancing satisfaction. Collaborate with cross-functional teams to drive improvements and ensure a seamless...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$110K - $130K *

Manage the full sales cycle to open new mid-market and enterprise accounts, develop cross-sell opportunities, and grow customer relationships through high-value cybersecurity services, ensuring commer...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Transform lender relationships by managing program performance, onboarding, and communication. Collaborate with leadership to identify trends and opportunities, ensuring clarity and efficiency in fina...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Shape the future of sales by leading a dynamic team focused on customer retention and new business growth. Drive performance, develop talent, and foster cross-functional partnerships to enhance the Co...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$139K - $157K *

Transform client partnerships by leading innovative commerce strategies across major retail platforms. Drive growth through integrated marketing, operational excellence, and creative solutions, ensuri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Empower teams by enhancing technical capabilities across multiple sites, driving operational excellence through hands-on training and support. Engage in troubleshooting and continuous improvement to e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$109K - $207K *

Drive strategic enterprise sales to Fortune 100/500 companies, leveraging strong negotiation skills and a proven track record to exceed quotas in a dynamic and collaborative environment...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $160K *

Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$327K - $408K *

Lead the charge in shaping long-term marketing strategies and partnerships, overseeing a dynamic team to drive growth and enhance market positioning through innovative co-marketing initiatives and cro...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$160K - $190K *

Join a team that's redefining the Umbrella line of business by overseeing P&L, driving innovative strategies, and collaborating across departments to achieve profitable growth and enhance customer sat...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a dynamic team to evaluate strategic investments and growth opportunities in healthcare. Leverage market insights and financial modeling to shape multi-year business strategies, collaborating acr...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $92K *

Empower our channel partner division by managing operational activities, coordinating RFPs, and driving cross-functional collaboration to enhance sales and partner engagement. Your insights will shape...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $188K *

Unlock potential by managing high-profile accounts and driving sales growth through strategic planning and complex negotiations. Leverage your expertise to develop tailored solutions and exceed revenu...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Join a team that's redefining global events management by leading a dynamic program management function. Oversee flagship conferences and regional events, ensuring strategic alignment, operational exc...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.