Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$160K - $200K *

Join a dynamic team as a senior leader driving profitable growth in healthcare services. Oversee sales strategy, lead a high-performing team, and collaborate across functions to deliver innovative sol...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $125K *

Elevate your career by driving strategic sales initiatives in a dynamic environment. Leverage your expertise to build relationships, influence decision-makers, and expand market presence while managin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $215K *

Lead the charge in regional sales execution, driving product launch success and team performance through strategic planning, customer engagement, and cross-functional collaboration in a dynamic enviro...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Grow your career with a dynamic sales role, driving supply chain transparency for leading brands. Own the full sales cycle, engage senior stakeholders, and develop solutions that enhance customer valu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Transform the communications landscape by building a dynamic team that drives brand relevance through strategic earned media, influencer relations, and corporate communications, ensuring a consumer-fi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$230K - $345K *

Join a dynamic team as a Senior Manager, leading Account Executives to drive new business growth, enhance market presence, and foster a high-performance sales culture focused on accountability and cus...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $215K *

Drive regional sales success by leading launch execution, building high-performing teams, and fostering customer relationships. Leverage strong business acumen and collaborative skills to achieve sale...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join our dynamic Account Management Team to drive growth in the corporate occupier software market. Leverage your sales expertise to build lasting client relationships and uncover new opportunities wh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$150K - $200K *

Join a team that's driving sales excellence by developing strategic plans, fostering customer relationships, and leading a dynamic sales team to achieve ambitious revenue targets across diverse market...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$200K *

Lead the charge in driving enterprise growth marketing strategies, optimizing pipeline performance, and orchestrating cross-functional initiatives to scale demand generation and revenue outcomes acros...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $140K *

Join a team that's driving project success by leading technical initiatives, resolving complex challenges, and aligning outcomes with client objectives. Your expertise will enhance profitability and o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $152K *

Elevate the synergy between Sales strategy and technology delivery, translating business needs into actionable engineering specifications. Drive system enhancements and ensure seamless collaboration a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $230K *

Strategize and lead comprehensive marketing initiatives to drive customer acquisition, enhance brand presence, and support revenue growth across diverse business segments. Oversee a high-performing te...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Take ownership of transformational sales efforts within the Public Safety sector, leveraging your expertise in Microsoft solutions to foster relationships, drive pipeline growth, and deliver impactful...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $160K *

Join a dynamic team to lead large-scale NetSuite projects, enhancing client experiences through strategic project management and collaboration. Utilize your expertise in pre-sales and implementation t...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $383K *

Join us to lead the contracts function in a dynamic Federal contracting environment. Oversee a team of 20+ professionals, develop strategies, and negotiate complex contracts while fostering strong rel...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a dynamic team as you drive revenue growth in K12 and Higher Ed sectors, leading full-cycle sales and expanding market presence with innovative AI solutions that transform education...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Join a team that's transforming patient care access by owning the mid-market and enterprise pipeline, building partnerships, and navigating complex deals to drive impactful growth in a collaborative s...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Drive strategic and operational leadership for mortgage servicing, ensuring compliance, profitability, and exceptional service. Oversee portfolio management, technology integration, and business devel...

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Empower public-sector organizations by driving technology solutions in Washington. Develop new relationships, expand accounts, and collaborate with teams to enhance government operations and education...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $161K *

Accelerate progress at driving agency relationships and revenue growth in the commercial trucking sector. Manage a diverse portfolio of accounts while implementing best practices to enhance sales perf...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $140K *

Transform the renewable energy landscape by driving solar module sales in the Northwest. Leverage your expertise to build relationships, uncover opportunities, and achieve sales targets while managing...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$253K - $398K *

Shape the future of public sector sales by driving growth and building relationships with key stakeholders. Leverage your expertise to uncover opportunities and deliver impactful digital solutions tha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive operational excellence by leading the S&OP strategy, aligning resources with business goals, and optimizing capacity planning across the network to enhance efficiency and service delivery...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Drive revenue growth by managing key customer accounts and expanding market share in the envelope manufacturing sector. Leverage industry expertise and relationship-building skills to deliver tailored...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.