Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$260K - $265K *

Innovate the future of hospitality services by unifying existing platforms into a cohesive offering. Collaborate with leadership to define, build, and market a new service model that meets client need...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$90K - $110K *

Grow your career with a dynamic sales role focused on driving growth in industrial manufacturing. Engage with customers, manage the sales process, and achieve targets while building lasting relationsh...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$172K - $287K *

Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$230K - $285K *

Champion technology strategy and innovation across Health and Defense sectors. Lead enterprise technology direction, drive execution of solutions, and establish strategic partnerships to enhance compe...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $120K *

Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Accelerate progress at joint ventures with health systems, leading complex transactions from engagement to execution. Drive growth through partnerships, leveraging strategic relationships and operatio...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$160K - $190K *

Manage strategic sales relationships with national accounts to drive growth in value-based care. Collaborate with leadership teams, execute contract strategies, and support implementations to enhance...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$105K - $120K *

Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $235K *

Transform public safety operations by driving growth through strategic sales and relationship-building with fire departments and agencies. Own the sales cycle, deliver impactful demos, and collaborate...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $225K *

Unlock growth by leading strategic partnerships in the CDMO sector. Drive sales, nurture client relationships, and collaborate across teams to enhance market presence and customer satisfaction. Your e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $235K *

Join a team that's shaping the future of Medical Affairs by driving strategic client engagements and enhancing capabilities. This Director-level role balances client delivery and internal growth, focu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$80K - $95K *

Engage with mid-market clients to drive consultative sales, managing the full cycle from outreach to contract. Build trust with support leaders, demonstrating clear ROI and shaping the sales strategy...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $160K *

Drive your career with a strategic role in Product Operations, partnering with leaders to transform complex challenges into actionable insights, while enhancing cross-functional collaboration and leve...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$133K - $227K *

Empower financial institutions by strategizing and executing innovative ledger solutions. Engage with C-suite executives to drive modernization and enhance operational resilience, while managing the f...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Drive operational excellence by leading maintenance strategies and capital projects, enhancing asset reliability and performance in a fast-paced food manufacturing environment. Collaborate with cross...

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$175K - $210K *

Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Partner with us to drive growth in strategic enterprise accounts, managing complex sales cycles and building trust with security-focused buying committees. Leverage technical credibility to close mult...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $150K *

Unlock the potential of strategic accounts as you build lasting relationships, drive retention, and identify growth opportunities. Be the primary advocate for our major enterprise clients, ensuring sa...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$123K - $185K *

Lead K-12 sales initiatives in the Southeast, driving growth through strategic partnerships and culinary collaborations while enhancing product placements and bid success across school districts...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $150K *

Lead the charge in driving revenue growth by developing new business opportunities and managing client relationships in the robotics and automation sectors, while collaborating with technical teams to...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$92K - $134K *

Join a dynamic team to build client relationships, drive upsell opportunities, and enhance retention through tailored solutions. Leverage your expertise in facilities management and market assessments...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$115K - $135K *

Grow your career with leadership in business development, targeting the Behavioral Health sector. Leverage your expertise to drive sales, establish client relationships, and exceed financial goals whi...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$76K - $102K *

Engage in a dynamic role driving client acquisition in the Home-Based Care sector. You'll build a robust pipeline, execute sales strategies, and collaborate cross-functionally to enhance client experi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.