Welcome to Principal Scientist Jobs

Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.

Why Principal Scientist Jobs?

As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.

Our Offerings

We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.

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$100K - $130K *

Empower scientific advancement by driving LCMS innovation and cross-functional collaboration in pharmaceutical bioanalysis. Lead complex initiatives that align product strategy with emerging market ne...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Unlock potential by leveraging deep scientific expertise and technical skills to partner with customers, ensuring the delivery of complex SaaS solutions while driving integration and data architecture...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $185K *

Champion the transition of analytical methods from lab to manufacturing, ensuring the delivery of innovative neurological therapies through close collaboration across teams and management of external...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Discover innovative solutions as a Senior Project Manager guiding biopharmaceutical assays. Lead project execution, optimize bioanalytical techniques, and collaborate with stakeholders to drive advanc...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $130K *

Engage with cross-functional teams to implement and support lab integration solutions, ensuring timely delivery and alignment with customer scientific goals while enhancing operational success through...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform your career by leading complex epidemiology workstreams, guiding rigorous study designs, and mentoring teams to deliver impactful results in real-world evidence generation while ensuring hig...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive innovation as you design and implement AI solutions for clinical trials, collaborating closely with cross-functional teams to enhance data utilization and streamline processes through advanced m...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$113K - $181K *

Lead cutting-edge clinical data and AI initiatives with top hospitals to drive innovation in image-guided therapy. Partner with key stakeholders to translate clinical needs into impactful, scalable so...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Lead innovative projects in evidence synthesis, collaborating with multi-level teams to deliver comprehensive health technology assessments and mentor junior researchers in a fully remote environment...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $331K *

Pioneer the development of advanced ML models for lending and underwriting. Spearhead financial forecasting, leading a quantitative team to enhance valuation insights and market dynamics for collectib...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$152K - $190K *

Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...

US-AnywhereRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Information Technology

$163K - $221K *

Drive scientific leadership in pharmacokinetics for large molecule projects. Collaborate across multifunctional teams to advance drug development through strategic execution of bioanalytical and pharm...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Engage in the integration of Dotmatics into the Siemens ecosystem, leading technical initiatives and collaborating with stakeholders to ensure seamless execution and compliance across complex systems...

US-AnywhereRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $150K *

Develop high-performance web and mobile platforms by overseeing architecture and technical strategies for cutting-edge ad-tech solutions, focusing on server optimization and seamless data integration...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$213K - $273K *

Lead the technical vision for scalable backend systems, collaborating with cross-functional teams to translate product goals into executable strategies. Mentor engineers, drive architectural design, a...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Advance marketing effectiveness by leveraging data insights and analytics. Lead measurement strategies for integrated digital ecosystems, driving performance evaluations and guiding teams to inform st...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$238K - $330K *

Champion the future of transformative decision systems by guiding teams on optimizing offer strategies, conversion modeling, and systems design to enhance borrower experiences and improve marketplace...

US-AnywhereRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$70K - $95K *

Drive project success by leading civil operations in CCR disposal and landfill construction. Collaborate across teams to ensure environmental compliance while managing costs and schedules for large-sc...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $130K *

Contribute to clinical trial success by managing site engagement, ensuring compliance, and streamlining workflows. Leverage your expertise in diagnostics to optimize studies while collaborating across...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Join a team that's dedicated to enhancing clinical trial project outcomes. Oversee setup and operational documents while collaborating across departments to ensure client satisfaction and drive proces...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $185K *

Discover opportunities as a Principal Hydrogeologist, leading projects with multi-disciplinary teams, driving strategic growth in mining hydrogeology services, and enhancing client relationships while...

US-AnywhereRemote

1 week ago

  •   15+ years exp.  •   Energy & Utilities

$120K - $160K *

Join a team that's shaping the future of cybersecurity solutions. As a Principal Product Manager, you'll drive innovative offerings, serving diverse market segments while leveraging your extensive exp...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$176K - $221K *

Elevate operational efficiency by leading AI transformation initiatives across Finance, HRIS, and Legal. Deliver impactful projects that enhance automation and drive measurable business outcomes, ensu...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $100K *

Shape clinical development through precise medical writing and analysis. Collaborate on key projects, ensuring high-quality documentation for regulatory submissions and scientific publications, while...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Lead agronomic research for new crop commercialization, managing trials, collaborating with teams, and driving data analysis for sustainable agricultural practices while ensuring strong relationships...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What is the role of a Principal Scientist?question toggle

    A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.

  • How much does a Principal Scientist earn on average?question toggle

    The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.

  • What qualifications are required for Principal Scientist jobs?question toggle

    Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.

  • Can I find remote Principal Scientist jobs on Ladders?question toggle

    Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.