South Dakota, known for its diverse economy and strong job market, hosts a variety of high-paying job opportunities in different sectors. Whether you are looking for roles in healthcare, technology, finance, or other professional industries, Ladders has got you covered.
With a low unemployment rate and fast-growing industries, South Dakota is a promising place to level up your career. Explore the vast opportunities spread across the Mount Rushmore State with Ladders.
Navigate the professional job market in South Dakota with ease using our curated, vetted job postings. Join Ladders to discover the lucrative job opportunities in South Dakota that await you.
Average Salary: $119,458
Senior Product Marketing Manager
$170K - $190K *
Drive the creation of compelling marketing content that simplifies complex energy solutions for B2B audiences. Leverage technical expertise to enhance messaging and support commercial growth across di...
2 weeks ago
$120K - $162K *
Drive pharmacy operations as a licensed Pharmacist, ensuring compliance, safety, and exceptional customer care. Lead a dedicated team while managing workflow, performance metrics, and process improvem...
Reposted 2 weeks ago
$95K - $118K *
Empower safety excellence by managing EHS programs across multiple facilities, ensuring compliance and promoting a culture of health, safety, and continuous improvement. Collaborate with teams to driv...
2 weeks ago
Senior Manager, AI Red Team, Threat Operations
$208K - $281K *
Transform the AI security landscape by leading a Red Team focused on offensive operations. Build a high-performing team to drive strategic initiatives, enhancing security across AI systems while foste...
Reposted 2 weeks ago
$100K - $120K *
Engineer innovative solutions in a dynamic MultiValue environment, blending software development, database management, and systems support to enhance enterprise applications and ensure optimal perform...
Reposted 2 weeks ago
Registered Nurse (RN) - December 2026 New Grad
$69K - $101K *
Empower patient care by delivering comprehensive nursing services, collaborating with healthcare teams, and providing essential support and education to promote health and wellness. Ensure safety and...
2 weeks ago
REMOTE: Senior Product Manager
$120K - $145K *
Lead the charge in shaping impactful solutions as a Senior Product Manager, orchestrating product strategy and delivery in a cross-functional, fast-paced environment to enhance customer experiences an...
Reposted 2 weeks ago
Project Manager, Strategy and Operations (Research & Development)
$95K - $128K *
Lead the charge in advancing R&D effectiveness by managing strategic initiatives and operational improvements. Collaborate across functions to ensure the successful execution of vaccine development an...
2 weeks ago
$80K - $95K *
Lead territory growth and provider adoption by executing innovative sales strategies. Drive revenue expansion through customer engagement and effective pipeline management while ensuring compliance in...
2 weeks ago
$110K - $130K *
Unlock potential by designing and implementing scalable data pipelines using Azure services. Collaborate with various stakeholders to optimize data flows and deliver reliable data for enhanced decisio...
2 weeks ago
Construction Sales: Building Repair and Renovation
$68K - $118K *
Drive excellence in construction sales by delivering top-notch repair solutions, enhancing customer satisfaction, and managing projects efficiently to achieve high-quality results and brand loyalty...
2 weeks ago
Ground Station System Engineer III
$88K - $105K *
Champion the integration and development of satellite ground systems to support global Earth science initiatives through collaboration and technical innovation in a dynamic team environment...
2 weeks ago
Director, GTM Strategy & Market Intelligence
$135K - $160K *
Contribute to strategic GTM initiatives by analyzing markets and accounts, implementing scoring models, and guiding decision-making processes to drive business growth and competitive positioning effec...
2 weeks ago
$100K - $120K *
Unlock your potential by designing impactful onboarding and training programs that enhance sales team effectiveness. Collaborate with cross-functional leaders to equip sellers with essential tools and...
2 weeks ago
$90K - $120K *
Elevate your career by overseeing import compliance and logistics. Ensure adherence to U.S. trade laws, manage customs interactions, and streamline container shipments to optimize operations and drive...
2 weeks ago
$110K - $130K *
Manage large-scale, cross-functional projects by defining scope, budgets, and timelines. Lead teams through project lifecycle while ensuring alignment with contract and customer requirements, and main...
2 weeks ago
Territory Sales Representative, Endodontics
$70K - $125K *
Drive your career with a dynamic sales professional role focused on fostering relationships, pursuing new business, and ensuring customer satisfaction while achieving sales targets in the dental and h...
2 weeks ago
$150K - $185K *
Lead the charge in complex tax engagements, mentor a dynamic team, and enhance client service by delivering strategic tax solutions and compliance expertise. Collaborate across multiple jurisdictions...
2 weeks ago
VP, Digital & Analytics - remote opportunity
$175K - $200K *
Engage as a growth-oriented leader to optimize digital marketing strategies, enhance member engagement, and drive conversion rates across diverse audiences, leveraging data-driven insights and cross-c...
2 weeks ago
$199K - $260K *
Shape a high-performing accounting function by enhancing automation, building talent density, and ensuring a swift, clean financial close in a fast-paced environment focused on scaling operations with...
Reposted 2 weeks ago
Director, Sales Enablement & Strategic Deals
$125K - $150K *
Empower teams by shaping strategies that enhance sales capabilities and drive business value. Take ownership of enabling effective sales execution through structured training, deal shaping, and compre...
2 weeks ago
$90K - $140K *
Lead the charge in designing and implementing cutting-edge SASE solutions, enhancing networking and cloud security for distributed environments. Collaborate with cross-functional teams to advance secu...
2 weeks ago
$150K - $250K *
Grow results by leading a high-performing distribution network, focusing on strategy, agency development, and market expansion. Collaborate with cross-functional teams to drive profitability and stren...
2 weeks ago
$110K - $130K *
Champion successful project delivery by leading complex client engagements, managing resources, timelines, and budgets, all while ensuring exceptional communication and stakeholder engagement to foste...
2 weeks ago
$110K - $130K *
Lead enhancements in Salesforce HealthCloud to optimize solutions and integrations, collaborate with teams, and deliver scalable applications that ensure high-quality data and security compliance for...
Reposted 2 weeks ago
What kind of high-paying jobs are available in South Dakota?
South Dakota has a robust job market with high-paying positions in healthcare, IT, finance, manufacturing, and more.
Why should I consider working in South Dakota?
South Dakota is known for its diverse economy, low unemployment rate, and range of industries. It's a great location for professionals looking to advance their careers.
Can I find jobs that pay over $100000 in South Dakota?
Yes, at Ladders you can find many jobs in South Dakota that pay over $100000.
How can Ladders help me in finding high-paying jobs in South Dakota?
Ladders provide vetted, high-paying job postings and tools to help you navigate the professional job market in South Dakota.