Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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$95K - $115K *

Build robust software solutions by developing application and test code, while steering implementation decisions in a collaborative Agile environment. Contribute to complex architectures using modern...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$112K - $196K *

Drive innovation in software engineering by developing cutting-edge cyber tools. Collaborate with a dynamic team to enhance national defense capabilities while advancing your career in a fast-paced en...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$74K - $130K *

Unlock potential by joining a dynamic Agile team to develop critical enterprise software applications, leveraging modern technologies in a fast-paced environment for mission success...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$160K - $200K *

Drive innovation by designing and developing scalable backend services, collaborating closely with engineering teams to enhance platform performance and reliability while mentoring junior developers a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Explore innovative software solutions in a dynamic engineering environment, collaborating with a dedicated team to drive client success and enhance technical skills. Embrace a culture focused on probl...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $145K *

Optimize software development by owning complex features, leveraging AI tools, and collaborating with cross-functional teams to deliver high-quality, scalable solutions that meet business needs and te...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$225K - $265K *

Partner with us to lead a high-performing engineering team, driving innovation and efficiency in our travel marketplace. You'll manage project lifecycles, enhance collaboration, and champion a custome...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $145K *

Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $110K *

Transform your career by developing innovative software solutions in a collaborative Agile environment. Engage in all phases of the software development lifecycle while enhancing cybersecurity and ide...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Unlock potential by developing innovative software solutions using cutting-edge technologies. Collaborate closely with teams to create high-quality applications while adapting to new tools and process...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the charge in developing robust ML infrastructure and scalable applications, driving solutions for large-scale challenges while ensuring high-quality software design and functionality in a fast-p...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$103K - $181K *

Empower a dynamic Agile team in developing critical mission applications, utilizing your expertise in enterprise software development and fostering effective collaboration to enhance solutions for com...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $145K *

Explore the potential of AI in full-stack development while designing and delivering enterprise applications. Collaborate across teams and mentor engineers, ensuring your expertise shapes cutting-edge...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $180K *

Accelerate progress at the forefront of AI-native software development. Drive engineering excellence by orchestrating autonomous agents and maintaining high-quality standards in a FedRAMP-authorized e...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate our software engineering capabilities by designing and building modern, cloud-native data pipelines. Collaborate with diverse teams to ensure seamless project delivery and advocate for best pr...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$96K - $148K *

Lead the charge in designing and building secure integrations for enterprise ITSM platforms. Analyze data flows, enhance system connections, and ensure compliance while delivering resilient solutions...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$119K - $180K *

Lead the development of innovative web platforms, collaborating with cross-functional teams to enhance content management systems. Drive technical decisions and foster a culture of growth while ensuri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$100K - $130K *

Take ownership of developing innovative software solutions, leveraging new technologies and processes. Collaborate closely with customers to create high-quality applications while adapting to evolving...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Elevate incident response capabilities by developing dashboards and alerts, optimizing cloud performance, and ensuring security compliance. Collaborate with product teams to enhance IAM needs while dr...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Contribute to the development of a robust Kubernetes control plane, enhancing multi-cloud infrastructure and driving scalable architecture for enterprise-grade cloud services...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Innovate core infrastructure and systems for agent-native applications, ensuring high availability and performance while enabling a culture of developer efficiency and confidence in delivery...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive innovative software solutions by designing, developing, and testing systems-level software. Collaborate with cross-functional teams to meet operational specifications and enhance SAP functionali...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$96K - $154K *

Develop and maintain quality software for internal stakeholders, focusing on Python and AWS. Collaborate in an Agile environment, define architecture, and mentor junior developers while enhancing lega...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$200K - $245K *

Champion innovative software solutions by leading the design and implementation of scalable systems and APIs. Collaborate across teams to enhance user experiences while mentoring engineers and driving...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate healthcare delivery by developing AI solutions that enhance operations and resident experiences. Collaborate with teams to automate processes and improve clinical decision-making in senior ca...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.