Discover professional opportunities across South Dakota with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From established employers in Sioux Falls and Rapid City to opportunities in communities throughout the state, South Dakota offers career paths for experienced professionals seeking leadership, specialized expertise, and room to grow.
South Dakota’s economy includes healthcare, financial services, technology, manufacturing, agriculture, energy, and business services. Employers may seek professionals in areas such as executive leadership, operations, finance, sales, engineering, healthcare administration, and information technology. Browse current listings to see which roles and locations match your experience and goals.
Sioux Falls is a major center for healthcare, finance, and corporate services, while Rapid City supports opportunities in healthcare, tourism, government, and regional business. High-paying roles may also be available in smaller cities and communities, including remote or hybrid positions connected to South Dakota employers.
Senior-level searches often reward a focused approach. Highlight measurable accomplishments, leadership experience, specialized credentials, and results relevant to each role. Review compensation details and job requirements, and use Ladders to explore vetted openings that meet the $100,000-and-up salary threshold.
Whether you are already based in South Dakota or considering a move, browse available listings to identify opportunities that align with your skills, preferred location, and career ambitions. New roles can appear over time, so check back regularly for the latest high-paying professional jobs.
Average Salary: $121,112
Director of Property Accounting
$140K - $165K *
Shape the future of property accounting by leading a dynamic team, ensuring timely financial reporting, and driving innovative processes that enhance client trust and operational efficiency across mul...
1 week ago
Customer Marketing Manager, Retention & Advocacy
$95K - $115K *
Empower customer retention and advocacy by leading US-focused programs. Collaborate cross-functionally to enhance customer journeys, ensuring clear communication and value delivery while optimizing en...
1 week ago
Customer Journey Operations Manager
$120K - $150K *
Accelerate customer journey operations by driving scalable processes and systems. Collaborate cross-functionally to enhance customer success, technical support, and partner engagement, ensuring effici...
1 week ago
Senior Medical Science Liaison, South (Multiple Territories)
$190K - $220K *
Engage with key stakeholders as a Senior Medical Science Liaison, driving prelaunch and launch strategies. Build trusted relationships, deliver scientific insights, and influence adoption in a dynamic...
1 week ago
$111K - $145K *
Lead transformative IT projects from inception to completion, ensuring timely delivery and budget adherence. Collaborate across departments to translate business needs into actionable plans while mana...
1 week ago
Senior Software Engineer - Virtual Machines (RD222)
$125K - $150K *
Transform your career by owning complex software features that integrate virtual machines into a secure platform. Collaborate across teams to deliver innovative solutions while establishing strong eng...
1 week ago
Principal Solution Architect - Security
$165K - $231K *
Transform complex security challenges into innovative solutions for public-sector and commercial clients. Lead technical pre-sales efforts, collaborating with sales teams to deliver tailored architect...
1 week ago
$160K - $185K *
Unlock your potential by leading a dynamic team to drive channel partnerships, transforming opportunities into revenue-generating relationships across diverse verticals in a fast-growing ecosystem...
1 week ago
$165K - $195K *
Engage in strategic solution development for Federal Government initiatives, translating client needs into innovative technical strategies. Collaborate with cross-functional teams to deliver compellin...
1 week ago
$105K - $132K *
Join a team that's dedicated to optimizing employee benefits programs. You'll manage US benefits operations, enhance vendor performance, and shape global strategies, ensuring a seamless, employee-cent...
1 week ago
Hematology Therapeutic Specialist (LA North)
$110K - $130K *
Join a team that's dedicated to advancing hematology care by educating healthcare providers and driving demand for innovative therapies. Leverage your expertise to foster relationships and ensure a po...
1 week ago
D&T Sr Project Management Consultant - Talent Community
$110K - $130K *
Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...
Reposted 1 week ago
Oil & Gas/Chemical Segment Leader
$119K - $190K *
Deliver strategic growth in the Oil & Gas and Chemical sectors by identifying opportunities, building executive relationships, and enabling sales. Leverage industry expertise to shape market strategie...
1 week ago
$80K - $130K *
Lead dealership implementations by managing go-lives, training teams, and ensuring seamless integrations. Collaborate with stakeholders to optimize workflows and drive adoption, while traveling freque...
1 week ago
$100K - $120K *
Advance global clinical trials by leading cross-functional teams, ensuring compliance and operational excellence while managing timelines and budgets to deliver impactful results in Oncology research...
1 week ago
$135K *
Elevate client success by leading innovative training programs that enhance learning experiences. Drive product adoption and satisfaction through tailored onboarding and ongoing education, ensuring cl...
1 week ago
Customer Success Manager (Public Sector)
$95K - $115K *
Join a team that's dedicated to enhancing customer success in cybersecurity. Leverage your expertise to build trusted relationships, drive product adoption, and ensure client satisfaction while naviga...
1 week ago
Sr. Manager, Provider Data Operations & Attribution Integrity
$67K - $199K *
Empower operational excellence by leading provider data governance and attribution processes. Collaborate across departments to ensure data integrity, enhance reporting accuracy, and drive continuous...
1 week ago
Cloud Readiness Architect - Consumer Goods Cloud
$150K - $227K *
Unlock potential by driving customer success through strategic product insights and collaboration. Leverage your expertise to enhance product adoption and quality, ensuring a seamless experience acros...
1 week ago
$80K - $95K *
Lead and advance the Operations Quality Assurance program, establishing standards and leveraging analytics and AI to drive performance improvements across teams while fostering talent development and...
1 week ago
Director of Solar Construction, SDI Services
$172K - $215K *
Drive the execution of solar construction projects by leading a skilled team, ensuring compliance with safety standards, and optimizing drilling operations for stable foundations. Collaborate with sta...
1 week ago
$80K - $100K *
Partner with us to enhance client relationships and optimize account management. Drive operational strategies, support sales pursuits, and collaborate with leaders to improve performance and transpare...
1 week ago
$78K - $131K *
Inspire growth by partnering with leaders to design impactful learning experiences that enhance performance across teams. Drive initiatives that empower employees to achieve their goals and improve pr...
1 week ago
$110K - $130K *
Join a team that's dedicated to enhancing technical enablement for sales and engineering roles. You'll develop scalable training programs, manage onboarding, and create hands-on resources to ensure fl...
1 week ago
Epic Application Analyst - Beacon
$80K - $95K *
Drive the design, build, testing, and support of applications, ensuring optimal functionality and user satisfaction while collaborating with interdisciplinary teams to enhance workflows and resolve co...
1 week ago
What South Dakota jobs on Ladders pay $100,000 or more?
Ladders features vetted professional jobs with salaries of $100,000 or more. South Dakota listings may include senior roles in healthcare, finance, technology, operations, sales, engineering, and executive leadership, depending on current openings.
Which South Dakota cities have high-paying jobs?
Sioux Falls and Rapid City are prominent employment centers, and opportunities may also be available in other South Dakota communities or through remote and hybrid roles. Browse current listings for specific locations.
Are remote jobs available to South Dakota residents?
Some employers advertise remote or hybrid positions that can be performed from South Dakota. Check each listing for its location, residency, and work-arrangement requirements.
How can I find senior-level jobs in South Dakota?
Search South Dakota listings by role, location, and relevant keywords, then review requirements and compensation. Tailor your application to emphasize leadership, specialized expertise, and measurable accomplishments.
Does Ladders verify South Dakota job listings?
Ladders focuses on vetted professional opportunities paying $100,000 or more. Review each posting for employer details, responsibilities, location, and compensation information before applying.